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Concepts and Case Studies in Chemical Biology
  • Language: en
  • Pages: 468

Concepts and Case Studies in Chemical Biology

Retaining the proven didactic concept of the successful "Chemical Biology - Learning through Case Studies", this sequel features 27 new case studies, reflecting the rapid growth in this interdisciplinary topic over the past few years. Edited by two of the world's leading researchers in the field, this textbook introduces students and researchers to the modern approaches in chemical biology, as well as important results, and the techniques and methods applied. Each chapter presents a different biological problem taken from everyday lab work, elucidated by an international team of renowned scientists. With its broad coverage, this is a valuable source of information for students, graduate students, and researchers working on the borderline between chemistry, biology, and biochemistry.

Chemical Biology
  • Language: en
  • Pages: 240

Chemical Biology

  • Type: Book
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  • Published: 2004-08-06
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  • Publisher: Wiley-VCH

Take your first steps in combinatorial synthesis or synthesize bioactive molecules such as antibiotics. Search for mutations in DNA using chemical probes or perform a proteome analysis in yeast. The present selection of 12 inspiring experiments is tailored for maximum learning effect at minimal expense of time and equipment. Almost all currently used laboratory techniques in synthesis and analysis of bioactive compounds are represented at least once. Abundant practical hints are complemented by a thorough treatment of the underlying theory and mechanisms.

Chemical Biology
  • Language: en
  • Pages: 304

Chemical Biology

  • Type: Book
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  • Published: 2009-04-20
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  • Publisher: Wiley-VCH

This first book to adopt a problem-based approach teaches the true basics of the subject through illustrated everyday case studies. The editor's extensive experience in writing textbooks and his close relationship to the authors ensure that the contributions are presented in a pedagogically uniform and highly motivating fashion. Each chapter introduces a different biological problem taken from everyday lab work, such that students learn how to think in order to solve problems in biology by using techniques and tools taken from chemistry. A must-have for students in chemistry, biology and biochemistry.

The Noughties Brought to Book
  • Language: en
  • Pages: 157

The Noughties Brought to Book

  • Type: Book
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  • Published: 2010-05-25
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  • Publisher: Lulu.com

Why music doesn't add up, what The Simpsons can teach us about science, whether Juana la Loca wasn't crazy after all, and what's behind the gaseous veil of Saturn's moon Titan ' these are just some of the questions addressed in the more than 70 reviews and essay reviews from the years 2000 to 2009 collected in this volume. They cover books about science, ranging from the academic to the popularized kind, but there are also books about cultural topics and even a few novels scattered in for good measure. Most of these books reviewed haven't found a massive amount of attention, although some of them should have, at least in the reviewer's opinion. And even if the book under review wasn't all that good, the format of an essay review allows the author to have a go at presenting the subject matter his own way. All in all, a reflection of what happened during the noughties in the worlds of science and culture, and off the beaten track.

Non-Natural Amino Acids
  • Language: en
  • Pages: 350

Non-Natural Amino Acids

By combining the tools of organic chemistry with those of physical biochemistry and cell biology, Non-Natural Amino Acids aims to provide fundamental insights into how proteins work within the context of complex biological systems of biomedical interest. The critically acclaimed laboratory standard for 40 years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. With more than 400 volumes published, each Methods in Enzymology volume presents material that is relevant in today's labs -- truly an essential publication for rese...

Chemical Biology
  • Language: en
  • Pages: 448

Chemical Biology

Chemical biology utilizes chemical principles to modulate systems to either investigate the underlying biology or create new function. Over recent years, chemical biology has received particular attention of many scientists in the life sciences from botany to medicine. This book contains an overview focusing on the research area of protein purification, enzymology, vitamins, antioxidants, biotransformation, gene delivery, signaling, regulation and organization. Particular emphasis is devoted to both theoretical and experimental aspects. The textbook is written by international scientists with expertise in synthetic chemistry, protein biochemistry, enzymology, molecular biology, drug discovery and genetics many of which are active chemical, biochemical and biomedical research. The textbook is expected to enhance the knowledge of scientists in the complexities of chemical and biological approaches and stimulate both professionals and students to dedicate part of their future research in understanding relevant mechanisms and applications of chemical biology.

Enzyme Systems that Metabolise Drugs and Other Xenobiotics
  • Language: en
  • Pages: 600

Enzyme Systems that Metabolise Drugs and Other Xenobiotics

This definitive reference work describes in detail the enzyme systems that participate in the metabolism of xenobiotics, particularly medicinal drugs. Each chapter focuses on a specific enzyme system, emphasising its role in the activation and detoxication of chemicals. Aspects discussed critically include: * enzyme function in the metabolism and bioactivation of xenobiotics * substrate specificity * tissue distribution * species distribution (to include laboratory animals and humans) * hormonal regulation * sex differences * modulation by prior exposure to other chemicals * age-dependent expression * pharmacogenetics and modulation by disease. Enzyme Systems that Metabolise Drugs and Other Xenobiotics will be essential reading for industrial research scientists working in the fine chemicals and pharmaceutical industries, especially those concerned with the safety evaluation of chemicals, and investigating their metabolism, pharmacokinetic characteristics and toxicological properties. The nature and scope of the book will also make it attractive to the research toxicologist and to postgraduate students studying toxicology, as well as to clinicians and pharmacists.

Choice
  • Language: en
  • Pages: 594

Choice

  • Type: Book
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  • Published: 2009
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  • Publisher: Unknown

None

The British National Bibliography
  • Language: en
  • Pages: 2744

The British National Bibliography

  • Type: Book
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  • Published: 2009
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  • Publisher: Unknown

None

Small Molecule — Protein Interactions
  • Language: en
  • Pages: 228

Small Molecule — Protein Interactions

  • Type: Book
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  • Published: 2014-03-12
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  • Publisher: Springer

Based on the international workshop on 'Small Molecule - Protein Interactions' held in Berlin, April 24-26, 2002, researchers from industry and academic laboratories describe novel and efficient ways selecting promising new drug targets and developing small molecule inhibitors against them. The structure of the book corresponds to the different aspects of the drug discovery process. All chapters are written by leading experts in the field, who present and discuss the most recent state-of-the-art tools and techniques for the development of novel drugs. The value of the book lies in surveying and summarizing the approaches taken by different companies and institutions giving the reader a balanced view on the use of the latest techniques on the one hand and experience-based assistance in selecting appropriate tools for their own work on the other hand.