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Since the early 1970s, the Inuit of Arctic Quebec have struggled to survive economically and culturally in a rapidly changing northern environment. The promotion and maintenance of Inuktitut, their native language, through language policy and Inuit control over institutions, have played a major role in this struggle. Language, Politics, and Social Interaction in an Inuit Community is a study of indigenous language maintenance in an Arctic Quebec community where four languages - Inuktitut, Cree, French, and English - are spoken. It examines the role that dominant and minority languages play in the social life of this community, linking historical analysis with an ethnographic study of face-to-face interaction and attitudes towards learning and speaking second and third languages in everyday life.
Because the bakers and their bread were central to Parisian daily life, Kaplan's study is also a comprehensive meditation on an entire society, its government, and its capacity to endure.
Over the last 50 years, drug development and clinical trials have resulted in successful complete responses in diseases such as childhood leukemia, testicular cancer and Hodgkin's disease. We are still, however, confronted with over 500,000 cancer-related deaths per year. Clearly, the phenomenon of drug resistance is largely responsible for these failures and continues to be an area of active investigation. Since the last volume in this series, we have learned that the energy-dependent drug efflux protein, p-glycoprotein, encoded by the MDR 1 gene, is a member of a family of structurally related transport polypeptides, thus allowing us to explore the relationship between structure and functi...
This authoritative, timely, and comprehensively referenced compendium on the bacteriophages explores current views of how viruses infect bacteria. In combination with classical phage molecular genetics, new structural, genomic, and single-molecule technologies have rendered an explosion in our knowledge of phages. Bacteriophages, the most abundant and genetically diverse type of organism in the biosphere, were discovered at the beginning of the 20th century and enjoyed decades of used as anti-bacterial agents before being eclipsed by the antibiotic era. Since 1988, phages have come back into the spotlight as major factors in pathogenesis, bacterial evolution, and ecology. This book reveals their compelling elegence of function and their almost inconceivable diversity.Much of the founding work in molecular biology and structural biology was done on bacteriophages. These are widely used in molecular biology research and in biotechnology, as probes and markers, and in the popular method of assesing gene expression.
Sheridan presents a literary biography of one of the most important writers of the 20th century--an intimate portrait of the reluctantly public man, whose work was deeply and inextricably entangled with his life. 35 halftones.