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Studies in Natural Products Chemistry
Studies in Natural Products Chemistry, Volume 14: Stereoselective Synthesis, Part I is a collection of discourses on the stereoselective synthesis of the anticancer anthrucycline antibiotics; tetramic acid antibiotics; 3-and 4-deoxyhexoses; polysaccharides; levoglucosenone as precursor to natural products; synthesis of oligoribonucleotides; and oxidation of guaiazulene. This volume deals with a broad range of natural products focusing on the synthesis of antibiotics and anticancer agents — anthracyclines, tetramic acid, taxodione, vinblastine, and vincristine. These aforementioned drugs are used for the treatment of cancer (anthracyclines) and Hodgkin's disease and childhood acute leukemia...
Anthracycline Chemistry and Biology I
With contributions by numerous experts
Malaria Immunology
Despite extensive efforts to control it, malaria is still one of the most devastating infectious diseases worldwide. This book, now in its second edition, provides a broad and up-to-date overview of the rapidly expanding field of malaria immunology and its importance in the control of this disease. The first section deals with the malaria parasite and its interactions with both the vertebrate host and the mosquitoes which transmit the disease. In the second part, the mechanisms of immunity and their regulation by environmental and genetic factors are discussed. Finally, this volume contains several chapters on malaria vaccine development, describing the application of the most recent vaccine technologies as well as ongoing and planned vaccine trials. Authored by well-recognized experts, this volume not only demonstrates the rapid progress being made in the search for vaccines against malaria, but also broadens our understanding of immunity to infection in general. It is therefore highly recommended reading for all scientists and professionals in the fields of immunology, infection and vaccine development.
Advances in Water and Wastewater Treatment Technology
This book is the result of the international symposium, "Establishment and Evaluation of Advanced Water Treatment Technology Systems Using Functions of Complex Microbial Community", organized in 2000 at the University of Tokyo. The volume presents the most recent progress in application of microbial community analysis, health-related microorganisms management, nutrient removal, waste sludge minimization and materials recovery, and water management in tropical countries. Included in this work are the following major topics in wastewater treatment: application of various innovative techniques of molecular biology such as FISH, DGGE to microbial community analysis of various types of wastewater...
Autophagy: Biology and Diseases
This book series consists of 3 volumes covering the basic science (Volume 1), clinical science (Volume 2) and the technology and methodology (Volume 3) of autophagy. Volume 1 focuses on the biology of autophagy, including the signaling pathways, regulating processes and biological functions. Autophagy is a fundamental physiological process in eukaryotic cells. It not only regulates normal cellular homeostasis, and organ development and function, but also plays an important role in the pathogenesis of a wide range of human diseases. Thanks to the rapid development of molecular biology and omic technologies, research on autophagy has boomed in recent decades, and more and more cellular and animal models and state-of the-art technologies are being used to shed light on the complexity of signaling networks involved in the autophagic process. Further, its involvement in biological functions and the pathogenesis of various diseases has attracted increased attention around the globe. Presenting cutting-edge knowledge, this book series is a useful reference resource for researchers and clinicians who are working on or interested in autophagy.
Introduction to Neuro-Fuzzy Systems
Fuzzy sets were introduced by Zadeh (1965) as a means of representing and manipulating data that was not precise, but rather fuzzy. Fuzzy logic pro vides an inference morphology that enables approximate human reasoning capabilities to be applied to knowledge-based systems. The theory of fuzzy logic provides a mathematical strength to capture the uncertainties associ ated with human cognitive processes, such as thinking and reasoning. The conventional approaches to knowledge representation lack the means for rep resentating the meaning of fuzzy concepts. As a consequence, the approaches based on first order logic and classical probablity theory do not provide an appropriate conceptual framewo...
Index Medicus
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
