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Regulation and targeting of enzymes mediating Parkinson’s disease pathogenesis: focus on Parkinson’s disease Kinases, GTPases and ATPases
  • Language: en
  • Pages: 164

Regulation and targeting of enzymes mediating Parkinson’s disease pathogenesis: focus on Parkinson’s disease Kinases, GTPases and ATPases

Understanding the molecular pathogenesis of Parkinson’s disease (PD) is a priority in biomedical research and a pre-requisite to improve early disease diagnosis and ultimately to developing disease-modifying strategies. In the past decade and a half, geneticists have identified several genes that are involved in the molecular pathogenesis of PD. They not only identified gene variants segregating with familial forms of PD but also genetic risk factors of sporadic PD via genome-wide association studies (GWAS). Understanding how PD genes and their gene products function holds the promise of unraveling key PD pathogenic processes. Therefore the precise cellular role of PD proteins is currently...

LRRK2 - Fifteen Years From Cloning to the Clinic
  • Language: en
  • Pages: 281

LRRK2 - Fifteen Years From Cloning to the Clinic

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Recent Advances in Parkinson's Disease
  • Language: en
  • Pages: 578

Recent Advances in Parkinson's Disease

  • Type: Book
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  • Published: 2020-04-02
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  • Publisher: Elsevier

Recent Advances in Parkinson ́s Disease Research, Volume 252, represents a follow-up on two previous volumes presented in the Progress in Brain Research series, Volumes 193 and 193, both published in 2010. It contains a collection of overview articles written by leading researchers in Parkinson's, discussing the most important advances made in basic, translational and clinical research. Topics of note in this new release include What can we learn from iPS cell models of PD, What can we learn from animal models of PD?, Molecular basis of selective neuronal vulnerability in PD, Role of innate and adaptive immunity in Parkinson ́s disease, and much more.

Leucine-Rich Repeat Kinase 2 (LRRK2)
  • Language: en
  • Pages: 280

Leucine-Rich Repeat Kinase 2 (LRRK2)

  • Type: Book
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  • Published: 2017-03-28
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  • Publisher: Springer

This is the first book to assemble the leading researchers in the field of LRRK2 biology and neurology and provide a snapshot of the current state of knowledge, encompassing all major aspects of its function and dysfunction. The contributors are experts in cell biology and physiology, neurobiology, and medicinal chemistry, bringing a multidisciplinary perspective on the gene and its role in disease. The book covers the identification of LRRK2 as a major contributor to the pathogenesis of Parkinson's Disease. It also discusses the current state of the field after a decade of research, putative normal physiological roles of LRRK2, and the various pathways that have been identified in the search for the mechanism(s) of its induction of neurodegeneration.

Index of Patents Issued from the United States Patent Office
  • Language: en
  • Pages: 2300

Index of Patents Issued from the United States Patent Office

  • Type: Book
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  • Published: 1975
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  • Publisher: Unknown

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Molecular Biology of the Cell
  • Language: en
  • Pages: 790

Molecular Biology of the Cell

  • Type: Book
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  • Published: 2006
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  • Publisher: Unknown

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Index of Patents Issued from the United States Patent and Trademark Office
  • Language: en
  • Pages: 1968

Index of Patents Issued from the United States Patent and Trademark Office

  • Type: Book
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  • Published: 1992
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  • Publisher: Unknown

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State
  • Language: en
  • Pages: 348

State

  • Type: Book
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  • Published: 1995
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  • Publisher: Unknown

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Newsletter
  • Language: en
  • Pages: 64

Newsletter

  • Type: Book
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  • Published: 1992
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  • Publisher: Unknown

None

Chess Life
  • Language: en
  • Pages: 622

Chess Life

  • Type: Book
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  • Published: 1997
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  • Publisher: Unknown

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