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The Biochemistry of the Carotenoids
The carotenoids are not only amongst the most widespread of the naturally occurring groups of pigments, but probably also have the most varied functions; witness their known roles in photokinetic responses of plants, in phototropic responses of fish and as vitamin A precursors in mammals and birds. Pigments with such wide distribution and such diverse functions are obviously of great interest to biological scientists with very different specializa tions, especially as it is unlikely that the study of the functions of carotenoids is anywhere near complete. The primary aim of the present work is to discuss the distribution, bio genesis and function of the carotenoids throughout the plant and a...
Targets and Emerging Therapies for Schizophrenia
New and emerging directions in pharmaceutical research to better treat schizophrenia Although the dopamine hypothesis has been the cornerstone of schizophrenia therapeutics, it is clear that dopamine-based approaches do not treat all aspects of the disease. Moreover, many schizophrenia patients fail to respond to current antipsychotics. Integrating chemistry, biology, and pharmacology, this book explores emerging directions in pharmaceutical research for drug targeting and discovery in order to find more effective treatments for schizophrenia, one of the most serious and widespread psychiatric diseases. Targets and Emerging Therapies for Schizophrenia presents the basics of schizophrenia, dr...
Primer of Ecological Restoration
The pace, intensity, and scale at which humans have altered our planet in recent decades is unprecedented. We have dramatically transformed landscapes and waterways through agriculture, logging, mining, and fire suppression, with drastic impacts on public health and human well-being. What can we do to counteract and even reverse the worst of these effects? Restore damaged ecosystems. The Primer of Ecological Restoration is a succinct introduction to the theory and practice of ecological restoration as a strategy to conserve biodiversity and ecosystems. In twelve brief chapters, the book introduces readers to the basics of restoration project planning, monitoring, and adaptive management. It ...
Reading EEGs: A Practical Approach
Reading EEGs: A Practical Approach focuses on pattern recognition and pattern comparison. The concepts of pattern recognition are developed in a logical fashion based on appearance rather than disease process. The book teaches waveform recognition so that the reader can generate a differential diagnosis based on that recognition. This book also incorporates a question-and-answer format that is effective for students at multiple levels of training. A unique feature of the book is that it follows a teaching methodology in which concepts are developed sequentially and logically.
New Tide of Natural Product Chemistry
This book highlights recent research and advances in natural product chemistry written by promising young researchers in this field who have played a central role for recent innovative advancements. The book consists of seventeen chapters covering novel bioactive natural products, uncovering life phenomena with natural products, biosynthesis of natural products, total synthesis of complex natural products by innovative strategies, and drug discovery using natural products. Each chapter begins with a brief and easy-to-understand introduction, then presents the cutting-edge research in each individual specialty. This book is not only a practical and essential reference resource for natural product chemists, medicinal chemists, synthetic organic chemists, biochemists, pharmacologists, as well as the pharmaceutical and biotechnological industries, but is also a useful guide to understanding new and emerging trends in this field.
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Biotechnology of Vitamins, Pigments and Growth Factors
Vitamins and related growth factors belong to the few chemicals with a positive appeal to most people; the name evokes health, vitality, fitness, strength . . . . each one of us indeed needs his daily intake of vitamins, which should normally be provided via a balanced and varied diet. However, current food habits or preferences, or food processing and preservation methods do not always assure a sufficient natural daily vitamin supply, even for a healthy human being; this is all the more true for stressed or sick individuals. Although modern society is seldom confronted with the notorious avitaminoses of the past, they do still occur frequently in overpopulated and poverty- and famine-struck...
The Poetic and Real Worlds of César Vallejo (1892-1938)
The world-renowned Peruvian poet César Vallejo (1892-1938) was also a journalist, essayist, novelist and would-be dramatist. The study of his life and work has encountered problems since the 1950s, stemming from the fact that half of his writing was published posthumously under editorship of doubtful accuracy. The matter is further complicated in that his non-poetic work has been neglected in favour of his verse. A Struggle between Art and Politics reviews the evidence -- literary and historical -- now reliably to hand, and assesses the often conflicting body of opinion his work has generated. Three essential questions are pertinent: Where should Vallejo be placed in the canon of twentieth-...
Modern Methods in Stereoselective Aldol Reactions
The selective formation of bondings between molecules is one of the major challenges in organic chemistry, and the so-called aldol reaction is one of the most important for this purpose. These reactions are a highly useful tool for developing such novel substances as natural products and pharmaceuticals. Likes its highly successful and much appreciated predecessor, "Modern Aldol Reactions", this ready reference provides a systematic overview of methodologies for installing a required configuration during an aldol addition step, but shifts the focus so as to cover the latest developments. As such, it presents a set of brand new tools, including vinylogous Mukaiyama-aldol reactions and substrate-controlled aldol reactions, as well as asymmetric induction in aldol additions. Furthermore, new developments in existing stereoselective aldol additions are described, such as the deployment of supersilyl groups or organocatalyzed aldol additions. All of these methodologies are presented in the context of their deployment in the total synthesis of natural products.
