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Brain Mapping: The Methods
The number of scientists and laboratories involved with brain mapping is increasing exponentially; and the second edition of this comprehensive reference has also grown much larger than the first (published in 1996), including, for example, five chapters on structural and functional MRI where the fi
MRCPCH
In this second edition, new questions have been added and existing material has been updated. The book's hybrid format bridges the gap between standard MCQ books and textbooks. It contains 280 exam-based paediatric MCQs written by a team of subject specialists. Each question is accompanied by the correct answer, plus a page-long subject summary focusing on the specific topics likely to occur in the examination, including lists, mnemonics and bullet points. This new format is a response to requests from exam candidates for longer teaching notes to counteract the need to refer to unncessarily detailed textbooks.
MRCPCH 1
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Pioneering Stem Cell/Gene Therapy Trials
The first unequivocal success for Gene Therapy was reported in April 2000 for X-SCID patients. Pioneering stem cell/gene therapy clinical trials are the focus of this book. Therapy successes such as the X-SCID trial and improved ADA-SCID ones are presented together with pioneering angio/vasculogenic clinical trials mediated either by transient gene therapy or emerging autologous stem cell transplantation. Highlights also include 1) promises of the breakthrough combination of stem cell- and transient gene-therapy, 2) gene therapy trials for neurodegenerative disease on non-human primates where long-term gene therapy might involve brain stem cells, and 3) the first clinical trial with non-invasive monitoring of therapeutic gene expression as a prospective conclusion.
Hormones and Cancer
The series, Hormones in Health and Disease, was launched in 1993 to provide a scientific platform for investigators engaged in research on the biological actions of hormones and to anticipate relevance for their findings in clinical applications. The first volume of the series was dedicated to the discussion and understanding of molecular mechanisms by which steroid hormones influence target cells in normal and pathological conditions. With the diversity of information and the vast amount of literature on steroid hormone physiology, a more thorough treatment of Hormones and Cancer was identified as a timely topic. In this second volume in the series, Dr. Wayne V. Vedeckis has success fully u...
Physics and Chemistry Basis of Biotechnology
At the end of the 20th century, a tremendous progress was made in biotechnology in its widest sense. This progress was largely possible as a result of joint efforts of top academic researchers in both pure fundamental sciences and applied research. The surplus value of such interdisciplinary approaches was clearly highlighted during the 9th European Congress on Biotechnology that was held in Brussels, Belgium (11-15 July, 1999). The present volume in the ‘Focus on Biotechnology’ series, entiteld ‘Physics and Chemistry Basis for Biotechnology’ contains selected presentations from this meeting, A collection of experts has made serious efforts to present some of the latest developments in various scientific fields and to unveil prospective evolutions on the threshold of the new millenium. In all contributions the emphasis is on emerging new areas of research in which physicochemical principles form the foundation. In reading the different chapters, it appears that more than ever significant advances in biotechnology very often depend on breakthroughs in the biotechnology itself (e.g.
Clinical Update on Inflammatory Disorders of the Gastrointestinal Tract
Digestive-disease-associated mortality accounts for a major part of all deaths in Western societies and inflammatory diseases such as GI infections, viral hepatitis, GERD or cancers due to chronic inflammation have a tangible economic and social impact. What further aggravates the situation is the fact that complex immunological disorders have surfaced where anti-infective treatments are not effective. Fortunately, due to breakthroughs in basic research that are being successfully translated into clinical practice, new treatment strategies are constantly evolving. In addition to the development of new therapeutic measures, however, it is also mandatory to review and periodically refine established treatment regimens to reflect current knowledge and ensure up-to-date medical care.Combining outstanding basic research reviews with cutting-edge treatment guidelines on inflammatory disorders of the GI tract, this book presents newly identified treatment targets and provides clinicians and practitioners in the field with a most useful account of the state of the art.
