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New Developments in Mania Research
Mania is a medical condition characterised by severely elevated mood. Mania is most usually associated with bipolar disorder, where episodes of mania may cyclically alternate with episodes of depression. (Note: not all mania can be classified as bipolar disorder, as mania may result from other diseases or causes. However, bipolar disorder is the "classic" manic disease). Hypomania is a less severe variant of mania, where there is less loss of control. Mania can be experienced at the same time as depression, in a mixed state. Dysphoric mania is primarily manic and a depressive mixed state is primarily depressed. This has caused speculation amongst doctors that mania and depression are two independent axes in a bipolar spectrum, rather than opposites. This book presents the latest research in this field.
Neurobiology of Mental Illness
The new edition of this definitive textbook reflects the continuing reintegration of psychiatry into the mainstream of biomedical science. The research tools that are transforming other branches of medicine - epidemiology, genetics, molecular biology, imaging, and medicinal chemistry - are also transforming psychiatry. The field stands poised to make dramatic advances in defining disease pathogenesis, developing diagnostic methods capable of identifying specific and valid disease entities, discovering novel and more effective treatments, and ultimately preventing psychiatric disorders. The Neurobiology of Mental Illness is written by world-renowned experts in basic neuroscience and the patho...
The Bio-clinical Interface
This book is a selection of papers presented recently at the annual scientific conferences -- known as "the bioclinical interface" -- held at Rouffac in Alsace. It puts the accent firmly on the modern aspects and contemporary problems of psychiatry. The first part of the book deals with biological and clinical areas. The second gives an almost exhaustive overview of the psychiatric applications of imaging and magnetic resonance spectroscopy.
Clinical Obsessive-Compulsive Disorders in Adults and Children
Clinical Obsessive-Compulsive Disorders in Adults and Children is a complete, comprehensive overview of OCD, covering its underlying causes, manifestations and treatment. The book begins by covering the basic science of OCD and its biological basis and mechanisms. It discusses the treatment for both adults and children with an emphasis on providing information for clinicians to use in their everyday practice. Using the latest information regarding evidence-based treatments, it takes the reader through medication options, including behavioural therapy, support groups and recent developments in surgical treatment. The clinical manifestations of OCD are covered, as well as the differentiation between OCD and other neuropsychiatric disorders with similar presentations. Chapters on spectrum illnesses including body dysmorphic disorder, impulse control disorders such as trichotillomania, and hoarding are also included. This book will appeal to all mental health professionals, from practitioners to researchers, working in the field of compulsive disorders.
The Neurobiological Basis of Suicide
With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment
The Handbook of Neuropsychiatric Biomarkers, Endophenotypes and Genes
Neuropsychiatric disorders such as schizophrenia, mood disorders, Alzheimer's disease, epilepsy, alcoholism, substance abuse and others are some of the most debilitating illnesses worldwide characterized by the complexity of causes, and lacking the laboratory tests that may promote diagnostic and prognostic procedures. Recent advances in neuroscience, genomic, genetic, proteomic and metabolomic knowledge and technologies have opened the way to searching biomarkers and endophenotypes, which may offer powerful and exciting opportunities to understand the etiology and the underlying pathophysiological mechanisms of neuropsychiatric disorders. The challenge now is to translate these advances int...
Diagnosis and Treatment of Autism
In 1987, The Swedish Medical Research Council's Group for Evaluation of Medical Technology approached me on the subject of organizing a conference on Autism - Diagnosis and Treatment. The original idea for this conference had come from a Stockholm politician, Leni Bjorklund, who had felt that, at least in Sweden, autism appeared to be an area in which conflicting views on etiology and treatment had led to children and parents not always receiving adequate help. Professors Agne Larsson, MD, Tore Schersten, MD and Bjorn Smedby, MD in particular showed a keen interest and it was decided to hold a State-of-the-Art-Conference on autism in Gothenburg. The State-of-the-Art-Conference on Autism -Dia...
Obsessive-Compulsive Disorder
Although Obsessive-Compulsive Disorder (OCD) has been known since the ancient times, the exact etiology and pathogenesis of OCD unfortunately still remain unknown. In addition, the therapeutic approaches elaborated for the treatment of OCD as a whole are not perfect, and this disorder as a rule is characterized by unfavorable course and lack of full therapeutic response. In the current book some modern data on pathogenesis, phenomenology and treatment of OCD are presented. Besides, the data on co-morbidity of OCD with other neurological and psychiatric disorders are also included. This book is intended for broad circle of readers, but mostly for psychiatrists, psychologists and neurologists.
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