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Over recent years, no other technique has grown to such importance as that of NMR spectroscopy. It is used in all branches of science where precise structural determination is required, and where the nature of interactions and reactions in solution is being studied. Annual Reports on NMR Spectroscopy has established itself as a means for the specialist and non-specialist alike to become familiar with new applications of the technique in all branches of chemistry, including biochemistry, and pharmaceutics.Once again, the Annual Reports on NMR Spectroscopy represents the best work in the field, both in applied and theoretical NMR spectroscopy. The high calibre reports in Volume 38 show the wide biological and physical applications that benefit from this analytical technique.
Molecular biology operates at three levels – genes, proteins and metabolites. This book is unique in that it provides a comprehensive description of an approach (metabonomics) to characterise the endogenous metabolites in a living system, complementing gene and protein studies (genomics and proteomics). These "omics" methods form the basis for understanding biology at a systems level. The Handbook of Metabonomics and Metabolomics aims to be the definitive work on the rapidly expanding subjects of metabolic profiling, metabolite and biomarker identification, encompassing the fields of metabonomics and metabolomics. It covers the principles of the subject, the analytical and statistical techniques used and the wide variety of applications.* comprehensive description of an approach (metabonomics) to characterise the endogenous metabolites in a living system, complementing gene and protein studies* aims to be the definitive work on the rapidly expanding subjects of metabolic profiling, metabolite and biomarker identification* covers the principles of the subject, the analytical and statistical techniques used and the wide variety of applications.
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The XIIIth International and the VIIth European Congress of Clinical Chemistry took place at the Netherlands Congress Centre in The Hague, from June 28th to July 3rd 1987. The Organizing Committee and the Scientific Committee for these combined congresses aimed to present the state-of-the-science as well as the state-of-the-art for those fields of clinical chemistry which show a strong progress and which will most probably inflict a great part of all clinical chemists. "Clinical Chemistry, an Overview" comprises almost all papers which were presented during the congress in 5 plenary lectures and 97 lectures during 24· symposia. The invited speakers, being experts in their fields of clinical...
This is a collection of papers on the use of Maharishi Transcendental Meditation® and TM-Sidhi programs to reduce offender recidivism. The papers provide a theoretical overview, new original research findings, and examples of practical implementation. Studies covering periods of 1-15 years indicate that employing the Maharishi Transcendental Meditation and TM-Sidhi programs may reduce recidivism by 35-50%.
Progress in Medicinal Chemistry
Includes subject section, name section, and 1968-1970, technical reports.
Although neonatal screening was begun only 20 years ago, and is consequently still in its early stages, it is already a classic example of efficient preventive pediatrics. At present, routine neonatal screening covering a satisfactory percentage of newborn babies is carried out in only a small part ofthe world. For some five diseases enough infants have been screened to give reasonably reliable information about the frequency of these diseases in various populations. Interesting differences are beginning to appear in popula tions of different ethnic and racial background. The medical importance of neonatal screening is especially obvious in metabolic diseases that are not too rare and for which effective treatment depends upon an early diagnosis, such as phenylketonuria, galactosemia, and - a more recent screening pro gram - hypothyroidism. About 1 of 4000 newborns is affected with hypothyroidism and can receive timely substitution with thyroid hormone. Of 34.5 million babies tested for phenylketonuria, 3000 cases have been diagnosed in time to prevent mental retardation by means of dietary therapy.