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The significantly expanded and updated new edition of a widely used text on reinforcement learning, one of the most active research areas in artificial intelligence. Reinforcement learning, one of the most active research areas in artificial intelligence, is a computational approach to learning whereby an agent tries to maximize the total amount of reward it receives while interacting with a complex, uncertain environment. In Reinforcement Learning, Richard Sutton and Andrew Barto provide a clear and simple account of the field's key ideas and algorithms. This second edition has been significantly expanded and updated, presenting new topics and updating coverage of other topics. Like the fir...
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This work has broad applications in clinical medicine, ranging from prevention and treatment of organ and bone marrow transplant rejection, management of various autoimmune disorders (for example, rheumatoid arthritis), skin disease and asthma. Whereas traditionally only a small repertoire of immunosuppressive agents was available for clinical use, recent discoveries have significantly increased the number of approved agents, resulting in numerous trials to further evaluate their potential. There is also considerable interest in the potential of cell-based therapies (particularly hematopoietic stem and dendritic cell therapy) of allo- and autoimmunity. Important recent advances in the immunotherapy of allergic diseases are also covered in this book. This volume is intended both for practising physicians and surgeons and for biomedical scientists at the graduate/postdoctoral levels, and is designed to provide the theory behind these various approaches to immunosuppression, and to provide state-of-the-art reviews of current developments in each area.
The Lloyd’s Register of Yachts was first issued in 1878, and was issued annually until 1980, except during the years 1916-18 and 1940-46. Two supplements containing additions and corrections were also issued annually. The Register contains the names, details and characters of Yachts classed by the Society, together with the particulars of other Yachts which are considered to be of interest, illustrates plates of the Flags of Yacht and Sailing Clubs, together with a List of Club Officers, an illustrated List of the Distinguishing Flags of Yachtsmen, a List of the Names and Addresses of Yacht Owners, and much other information. For more information on the Lloyd’s Register of Yachts, please click here: https://hec.lrfoundation.org.uk/archive-library/lloyds-register-of-yachts-online
This book makes available, for the first time in English translation, four of the principal narrative sources for the history of the Spanish kingdom of León-Castile during the 11th and12th centuries. The four chronicles were all composed in an unprecedented surge of Spanish historical writing between c.1110 and c.1150. Three of them focus primarily upon the activities of the kings of León-Castile as leaders of the Reconquest of Spain from the forces of Islam, and especially upon Fernando I (1037-65), his son Alfonso VI (1065-1109) and the latter's grandson Alfonso VII (1126-57). The fourth chronicle is a biography of the hero Rodrigo Díaz, better remembered as El Cid, and is the main source of information about his extraordinary career as a mercenary soldier who fought for Christians and Muslims alike.