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Parasitic Diseases
Reports on schistosomiasis epidemiology and clinical features in Africa and Brazil, and development of novel drugs that affect the worm tegument, and vaccine based on excretory-secretory products and Type 2 cytokines.
The Schistosomiasis Vaccine - It Is Time to Stand Up
Schistosomiasis is a severe parasitic disease, endemic in 74 developing countries with up to 600 million people, including many children, infected and 800 million at risk of contracting the disease following infection with Schistosoma mansoni, S. haematobium or S. japonicum. Disease burden is estimated to exceed 70 million disability-adjusted life-years, and leads to remarkably high YLD (years lived with disability) rates. Even more importantly, people with schistosomiasis are highly susceptible to malaria, tuberculosis and hepatic and acquired immunodeficiency viruses. There is only one drug, praziquantel, currently available for treatment and it has high efficacy, low cost, and limited sid...
UNESCO Science Report 2010
Analyses the current state of science around the globe as well the trends that have emerged since the previous report published in 2005.
Phylogeny and Ontogeny
This comprehensive treatise on the reticuloendothelial system is a project jointly shared by individual members of the Reticuloendothelial (RE) Society and bio medical scientists in general who are interested in the intricate system of cells and molecular moieties derived from these cells which constitute the RES. It may now be more fashionable in some quarters to consider these cells as part of what is called the mononuclear phagocytic system or the lymphoreticular system. Nevertheless, because of historical developments and current interest in the subject by investigators from many diverse areas, it seems advantageous to present in one comprehensive treatise current information and knowled...
An Overview of Tropical Diseases
Tropical diseases affect millions of people throughout the world and particularly in the developing countries. The millennium development goals had specifically targeted HIV/AIDS and Malaria for substantial reduction as well as Tuberculosis while many other tropical diseases have been neglected. The new sustainable development goals have not made such distinction and have targeted all diseases for elimination for the improvement of the quality of life of human beings on earth. The present book was developed to provide an update on issues relevant to the treatment of selected tropical diseases such as tuberculosis, malaria, leishmaniasis, schistosomiasis and ectoparasites such as chiggers which are widely distributed throughout the world. The control of these infections has been hampered by the development of drug resistance and the lack of the development of new and more effective drugs. The understanding of the biochemical processes underlying drug activity is therefore essential for the potential elimination of these infections.
Helminth Infections and their Impact on Global Public Health
This is a thoroughly revised edition of a well-received reference work on helminthiases and their impact on worldwide public health. The carefully presented collection covers both common and neglected helminth infections. Readers will discover an up-date overview to helminth epidemiology (including molecular typing), specific biological, immunological and immunopathological aspects, diagnosis and latest perspectives of control. New contributions give particular attention to economic consequences of helminthiases, deworming programs and future public health approaches, as well as most recent findings in host immune responses. Helminths are long-lived multicellular organisms that have co-evolv...
Current Progress and Challenges in the Development of a Hepatitis C Virus Vaccine
More than 70 million people worldwide are infected with hepatitis C virus, a major cause of liver cirrhosis, liver failure and hepatocellular carcinoma world-wide. In the last decade, this cancer has emerged as the second leading cause of cancer death and the global burden is increasing by two million new infections per year, mainly due to injection drug use. An effective vaccine will be the most effective means to contain the spread of this virus worldwide. The articles in this Research Topic describe the progress that has been made towards a preventive vaccine and the challenges that still need to be overcome to ultimately achieve this goal.
The Multimedia Encyclopedia of Women in Today′s World
This e-only volume expands and updates the original 4-volume Encyclopedia of Women in Today′s World (2011), offering a wide range of new entries and new multimedia content. The entries reflect such developments as the Arab Spring that brought women′s issues in the Islamic world into sharp relief, the domination of female athletes among medal winners at the London 2012 Olympics, nine more women joining the ranks of democratically elected heads of state, and much more. The 475 articles in this e-only update (accompanied by photos and video clips) supplement the themes established in the original edition, providing a vibrant collection of entries dealing with contemporary women′s issues around the world.
