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Small animal imaging has been recognized as an important tool in preclinical research. Nevertheless, the results of non-invasive imaging are often disappointing owing to choice of a suboptimal imaging modality and/or shortcomings in study design, experimental setup, and data evaluation. This textbook is a practical guide to the use of non-invasive imaging in preclinical research. Each of the available imaging modalities is discussed in detail, with the assistance of numerous informative illustrations. In addition, many useful hints are provided on the installation of a small animal unit, study planning, animal handling, and the cost-effective performance of small animal imaging. Cross-calibration methods, data postprocessing, and special imaging applications are also considered in depth. This is the first book to cover all the practical basics in small animal imaging, and it will prove an invaluable aid for researchers, students, and technicians.
The self-contained properties of discotic liquid crystals (DLCs) render them powerful functional materials for many semiconducting device applications and models for energy and charge migration in self-organized dynamic functional soft materials. The past three decades have seen tremendous interest in this area, fueled primarily by the possibility
Evolutionally optimized biomolecules and their complexes present attractive objects in the production of functionalized nanoobjects. Indeed, nucleic acid-based molecules are primary candidates as building blocks for development of nanoscale systems and devices. Written for chemists, physicists, molecular biologists, and students in related fields, Nanostructures and Nanoconstructions Based on DNA covers specific properties of metallic nanoparticles, and compares their properties with those related to nanoobjects formed by biological molecules. It also discloses details of formation and physicochemical peculiarities of the DNA nanostructures and DNA-based nanoconstructions. Furthermore, the b...
The Iranian Supreme Court has sentenced two teenagers to death. Their crime? Being involved in a three-year long homosexual relationship. Every gay rights organization in the Western Hemisphere has cried foul - and left it at that. Protest, they claim, is an adequate response to violence. But Major Matthew Martin, an instructor at the Marine Corps University, disagrees with their lack of action, and he’s feeling bored at the moment, having been relieved of his duties after giving a controversial speech at a local high school. The Major pulls together a few other disenchanted Marines and activists for a little side venture of his own: staging a private invasion of Iran and stopping the exec...
Based on graduate lectures given by the authors, Smectic and Columnar Liquid Crystals: Concepts and Physical Properties Illustrated by Experiments examines lamellar (smectic) and columnar liquid crystals, which, in addition to orientational order, possess 1D, 2D or 3D positional order. Topics include rheology and plasticity, ferroelectricity, analogies with superconductors, hexatic order and 2D-melting, equilibrium shapes, facetting, and the Mullins-Sekerka instability, as well as phase transitions in free films and membrane vibrations. Nematic and cholesteric liquid crystals are covered by the authors in a separate volume entitled Nematic and Cholesteric Liquid Crystals: Concepts and Physical Properties Illustrated by Experiments.
The discovery of the spatial structure of the double-stranded DNA molecule is one of the greatest achievements of science. It would not be an exaggeration to say that the DNA double helix is a distinguished symbol of modern biology. Divided into three parts, DNA Liquid-Crystalline Dispersions and Nanoconstructions covers the information presently available on the condensation of various forms of DNA and describes practical applications of the peculiar properties of the liquid-crystalline particles. Part 1 describes the main methods used for condensation of linear high- and low-molecular mass DNA, including their complexes with polycations and circular DNA Part 2 compares the state and reacti...
Liquid crystal displays were discovered in the 1960s, and today we continue to enjoy the benefits of that fundamental discovery and its translation into a wide variety of products. Like liquid crystals, polymers are unusual materials, and have similarly enjoyed a great deal of research attention because of their vast applications and uses and compl
Despite the large quantity of phenomenological information concerning the bulk properties of nematic phase liquid crystals, little is understood about the origin of the surface energy, particularly the surface, interfacial, and anchoring properties of liquid crystals that affect the performance of liquid crystal devices. Self-contained and unique,
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