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Evaluation of Biomarkers and Surrogate Endpoints in Chronic Disease
Many people naturally assume that the claims made for foods and nutritional supplements have the same degree of scientific grounding as those for medication, but that is not always the case. The IOM recommends that the FDA adopt a consistent scientific framework for biomarker evaluation in order to achieve a rigorous and transparent process.
Applying Big Data to Address the Social Determinants of Health in Oncology
The National Academies of Sciences, Engineering, and Medicine held the workshop Applying Big Data to Address the Social Determinants of Health in Oncology on October 28â€"29, 2019, in Washington, DC. This workshop examined social determinants of health (SDOH) in the context of cancer, and considered opportunities to effectively leverage big data to improve health equity and reduce disparities. The workshop featured presentations and discussion by experts in technology, oncology, and SDOH, as well as representatives from government, industry, academia, and health care systems. This publication summarizes the presentations and discussions from the workshop.
How to Prevent Prostate Problems
Presents the latest recommendations on how to prevent or correctly diagnose problems, as well as the pros and cons of various mainstream and alternative medicine treatment options.
Diseases of the Breast
Completely revised and updated, and now in full color throughout, the Fourth Edition of this definitive reference is a must for all clinicians who treat breast diseases. Leading experts summarize the current knowledge of breast diseases, including their clinical features, management, underlying biologies, and epidemiologies. In addition to complete coverage of malignant breast diseases, benign diseases are discussed in relation to subsequent breast cancer development. The book reviews all major clinical trials and summarizes the information they provide on early detection and management of breast cancer. Close attention is also given to the increasing importance of molecular biology and gene...
Scientific Standards for Studies on Modified Risk Tobacco Products
Smoking-related diseases kill more Americans than alcohol, illegal drugs, murder and suicide combined. The passage of the Family Smoking Prevention and Tobacco Control Act of 2009 gave the FDA authority to regulate "modified risk tobacco products" (MRTPs), tobacco products that are either designed or advertised to reduce harm or the risk of tobacco-related disease. MRTPs must submit to the FDA scientific evidence to demonstrate the product has the potential to reduce tobacco related harms as compared to conventional tobacco products. The IOM identifies minimum standards for scientific studies that an applicant would need to complete to obtain an order to market the product from the FDA.
An Ambulance of the Wrong Colour
A study on the ethical problems afflicting the health sector this work catalogues, through numerous cases, the misconduct of health professionals with regard to civilians, prisoners and military personnel; documents the misuse of scientific research, health professional and training institutions, and statutory councils for apartheid purposes; observes the failings of a profession trying to provide health care in the absence of a culture of human rights; and identifies ways in which human rights and ethical dilemmas recur in the current context of democratic transformation.
Perspectives on Biomarker and Surrogate Endpoint Evaluation
In 2010 the Institute of Medicine (IOM) recommended a framework for the evaluation of biomarkers in the chronic disease setting. Published in the book Evaluation of Biomarkers and Surrogate Endpoints in Chronic Disease, the framework is intended to bring consistency and transparency to the previously disparate process of biomarker evaluation. Following the book's release, the IOM convened a 2-day discussion forum in Washington, DC, in order to provide an opportunity for stakeholders to learn about, react to, and discuss the book. Presentations reviewed the authoring committee's work process, recommendations, and provided perspectives on the book from the point of view of participants. Thomas...
Last Minute Internal Medicine: A Concise Review for the Specialty Boards : A Concise Review for the Specialty Boards
When time is running out, reach for the one book that concentrates your board preparation into a single power-packed review If it's in here, you'll see it on the board exam! The most concise, yet comprehensive, Internal Medicine board exam prep available anywhere Logically organized by organ/system Focuses on “must know” facts that will appear on the exams and presents them in a quick summary format with numerous tables, lists, and concise narrative Covers every area tested on the primary Internal Medicine board exam Perfect as a recertification refresher and clinical reference An absolute must for those last weeks before the exam when a high-yield summary of key facts and pearls can make the difference between pass or fail Synopsis format maximizes content retention The super-effective quick-summary format allows you to: Devote your study time to what you really need to know Learn and remember more, in less time Evaluate your areas of strengths and weaknesses
Evaluation of Biomarkers and Surrogate Endpoints in Chronic Disease
Many people naturally assume that the claims made for foods and nutritional supplements have the same degree of scientific grounding as those for medication, but that is not always the case. The IOM recommends that the FDA adopt a consistent scientific framework for biomarker evaluation in order to achieve a rigorous and transparent process.
