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Methods in Endothelial Cell Biology
Endothelial cell biology has developed into a vibrant discipline and has become a critical instrument to study several disease processes on the cellular and molecular level. It is now widely recognized that dysfunctions of normal endothelial cell homeostasis are involved in some of the most important human diseases, including ischemic heart diseases, hypertension, atherosclerosis, tumors, diabetes, arthritis, and inflammation. Further, the increasing importance and recognition of the field of vascular biology in general requires in vitro and in vivo techniques in order to address the complex questions. Methods in Endothelial Cell Biology is a comprehensive practical "how-to"-guide summarizing the most relevant established techniques as well as a number of new emerging techniques. Easy-to-follow reliable protocols provide a useful lab bench resource for the experienced researcher and newcomer to the field.
Current Strategies in Cancer Gene Therapy
This book describes important developments and emerging trends in experimental and clinical cancer gene therapy. It reflects the tremendous advances made over recent years with respect to immunogenes, suicide genes and gene correction therapies, as well as in gene suppression and miRNA therapies. Many of the described strategies focus on the generation of more efficient and specific means of attack at known and novel cellular targets associated with tumor development and progression. The book also details parallel improvements in vector design, vector delivery, and therapeutic efficacy. It offers readers a stimulating, broad overview of advances in the field, linking experimental strategies to their clinical applications.
Everyday Revolutions
Women's everyday choices can engender revolutionary acts. This collection gathers essays that build upon this premise and examines the ways in which eighteenth-century women defied not only the restrictions their own culture sought to enforce, but also the restrictions our historical and literary understandings have created.
RNA Vaccines
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Sustainable Green Nanotechnology
The book places a strong emphasis on the significance of synthesizing nanomaterials and explores various methods of achieving this, with particular attention given to the production of environmentally friendly or "green" nanomaterials. This book illustrates the current gaps in the agriculture and food industry, and explores the potential applications of nanomaterials within this field. The integration of nanotechnology into the fields of biology and biochemistry holds the potential to exert a significant impact on the food industry in the future. This book comprehensively explores the various facets of design, utilization, and implementation of green nanomaterials within the agriculture and ...
Defoe's Footprints
In Defoe's Footprints, essays by prominent scholars of eighteenth-century literature salute Maximillian E. Novak's influence upon the study of Daniel Defoe. Best known today as the author of Robinson Crusoe, Defoe was a prolific writer in the late seventeenth and early eighteenth centuries who wrote novels, essays, pamphlets, and poems. Widely extending Novak's perspectives, this volume explores Defoe's place in the English novel and in literary developments of mimesis, realism, and popular mythology. The contributors locate Defoe in new ways within the complex symbolism and discourse of a turbulent world of burgeoning capitalism, Protestantism, imperialism, and economic speculation. With attention to Defoe's neglected writings as well as to his important works, this volume uncovers his distance from and influence on modern literature, paying tribute to Maximillian E. Novak by presenting new ideas about, and new readings of, Daniel Defoe.
Angiogenesis
Proceedings of the 5th Biannual International Meeting on Angiogenesis: From the Molecular to Integrative Pharmacology, held July 1-7, 1999, in Crete, Greece. Angiogenesis, as a vastly complex biological process, has challenged researchers from all basic scientific disciplines, including pharmacology, biochemistry, physiology, embryology and anatomy. The significance of this phenomenon for the study of disease states has also interested clinicians from a number of specialist fields. This multidisciplinary work reflects the growth of awareness of concepts such as angiogenesis based therapy, the enormous therapeutic and commercial potential of which has attracted major research and investment in recent years. This volume, which aims to bridge the gap between basic and clinical methodology and understanding, presents the most up-to-date developments in this field.
Speech and Drama
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AACR 2016: Abstracts 1-2696
The AACR Annual Meeting is a must-attend event for cancer researchers and the broader cancer community. This year's theme, "Delivering Cures Through Cancer Science," reinforces the inextricable link between research and advances in patient care. The theme will be evident throughout the meeting as the latest, most exciting discoveries are presented in every area of cancer research. There will be a number of presentations that include exciting new data from cutting-edge clinical trials as well as companion presentations that spotlight the science behind the trials and implications for delivering improved care to patients. This book contains abstracts 1-2696 presented on April 17-18, 2016, at the AACR Annual Meeting.
