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The ESC Textbook of Intensive and Acute Cardiovascular Care
The ESC Textbook of Intensive and Acute Cardiovascular Care is the official textbook of the Acute Cardiovascular Care Association (ACVC) of the ESC. Cardiovascular diseases (CVDs) are a major cause of premature death worldwide and a cause of loss of disability-adjusted life years. For most types of CVD early diagnosis and intervention are independent drivers of patient outcome. Clinicians must be properly trained and centres appropriately equipped in order to deal with these critically ill cardiac patients. This new updated edition of the textbook continues to comprehensively approach all the different issues relating to intensive and acute cardiovascular care and addresses all those involve...
SARS-CoV-2 Spike Protein Convergent Evolution
This book reviews the current knowledge of the globally circulating SARS-CoV-2 variants, highlights their distinct genetic characteristics and associated conformational changes in the viral spike protein, and profoundly discusses the mechanisms of convergent evolution that led to the rise of these mutated strains at different geographic regions during the Covid-19 pandemic. Furthermore, the book explores how these variants do and may impact the efficacy of established neutralizing antibody-based (nAb) vaccines and therapeutics by analysing latest in vivo and in vitro clinical data. Finally, the author discusses ways on how nAb Covid-19 treatment derived immune escape of SARS-CoV-2 could be minimized in the future.
Index Medicus
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Neurochemical Mechanisms in Disease
This newest volume of Advances in Neurobiology deals with the Neurochemistry of disease, with chapters covering both human diseases and animal “model” diseases.
La Confédération générale des vignerons du Midi
L'histoire singulière de la Confédération générale des vignerons est étroitement liée à celle des bouleversements subis entre 1907 et la fin du XXe siècle par une société viticole languedocienne ramenée à partir des années 1970 au rang de groupe social minoritaire dans la nouvelle société polymorphe du Languedoc actuel. Une grande partie des notables viticulteurs et de la masse des vignerons travaillant dans « le plus grand vignoble du monde » s'est vue obligée de quitter ses terres et de changer de métier et de société. Cette contribution, qui sur le plan universitaire avait pour ambition d'enrichir les apports de l'historiographie existante, est aussi un hommage à tous ces vignerons languedociens, à leur famille, et à leurs souffrances.
Progress in Heterocyclic Chemistry
This volume of Progress in Heterocyclic Chemistry (PHC) is the twelfth annual review of the literature, covering the work published on most of the important heterocyclic ring systems during 1999, with inclusions of earlier material as appropriate. As in PHC-11, there are also three specialized reviews in this year's volume. In the inaugural chapter, Michael Groziak revitalizes the field of boron heterocycles, a relatively obscure class of heterocycles, but with a promising future. Heterocyclic phosphorus ylides are similarly a little known but useful class of compounds and Alan Aitken and Tracy Massil have provided a comprehensive review of them in Chapter 2. In Chapter 3 Jack Li discusses the remarkably versatile palladium chemistry in pyridine alkaloid synthesis. The subsequent chapters deal with recent advances in the field of heterocyclic chemistry arranged by increasing ring size and with emphasis on synthesis and reactions.
