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Global Clinical Trials for Alzheimer’s Disease
Dementia is seriously disabling for those who have it and is often devastating for their caregivers and families. There are 7.7 million new cases of dementia each year, implying that there is a new case of dementia somewhere in the world every four seconds. The growth of dementia in the next 20 years will be much more acute in those countries with low and medium salaries. The World Health Organization wrote a report about dementia, calling on all governments to define dementia as a public health priority. Dementia clinical studies are becoming more and more complex with the number of enrolled patients increasing. Historically, the majority of patients recruited into clinical trials for medicine development have been from Western Europe and the US. However, clinical trials are increasingly recruiting patients from more countries, including developing countries. South America has larger urban populations than other emerging regions and could provide treatment-naïve patients for clinical trials.
History of Neurology
Handbook of Clinical Neurology: Volume 95 is the first of over 90 volumes of the handbook to be entirely devoted to the history of neurology. The book is a collection of historical materials from different neurology professionals. The book is divided into 6 sections and composed of 55 chapters organized around different aspects of the history of neurology. The first section presents the beginnings of neurology: ancient trepanation, its birth in Mesopotamia, ancient Egypt; the emergence of neurology in the biblical text and the Talmud; neurology in the Greco-Roman world and the period following Galen; neurological conditions in the European Middle Ages; and the development of neurology in the...
Progress in Alzheimer’s and Parkinson’s Diseases
This book represents the fourth ina series of international conferences related to Alzheimer's (AD) and Parkinson's (PO) diseases. The first one took place in EHat, Israel in 1985; the second in Kyoto, Japan, in 1989; and the third in Chicago, IL, USA in 1993. This book incorporates the proceedings of the Fourth International Conference on Pro gress in Alzheimer's and Parkinson's Diseases, held in EHat, Israel, on May 18-23, 1997. This Conference was the 41st in the series of annual OHOLO Conferences sponsored by the Israel Institute for Biological Research (IIBR). It was also conducted under the aus pices of the Alzheimer's Association Ronald and Nancy Reagan Research Institute, USA. The Co...
Human and Animal Models for Translational Research on Neurodegeneration: Challenges and Opportunities From South America
Neurodegenerative diseases are the most frequent cause of dementia, representing a burden for public health systems (especially in middle and middle-high income countries). Although most research on this issue is concentrated in first-world centers, growing efforts in South America are affording important breakthroughs. This emerging agenda poses new challenges for the region but also new opportunities for the field. This book aims to integrate the community of experts across the globe and the region, and to establish new challenges and developments for future investigation. We present research focused on neurodegenerative research in South America. We introduce studies assessing the interpl...
Global Clinical Trials for Alzheimer's Disease
Global Clinical Trials for Alzheimer’s Disease is a handy one-stop reference for researchers and physicians planning and conducting global clinical trials in this area. This book addresses important considerations that may arise during the successful design and execution of these trials, including site selection, local regulatory issues, pharmacogenomics, ethical matters and much more. Given the saturation of traditional clinical trial markets and the worldwide progression of Alzheimer’s disease, there is a need to focus on clinical trials in emerging markets and developing countries. This book provides you with a practical approach to recognizing the opportunities and tackling the chall...
Psychiatry and Neuroscience Update
This broad and thought-provoking volume provides an overview of recent intellectual and scientific advances that bridge the gap between psychiatry and neuroscience, offering a wide range of penetrating insights in both disciplines. The third volume on the topic in the last several years from a varying panel of international experts, this title identifies the borders, trends and implications in both fields today and goes beyond that into related disciplines to seek out connections and influences. Similar to its two Update book predecessors, Psychiatry and Neuroscience – Volume III presents the current state-of-the-art in the main disciplines – psychiatry and neuroscience – and attempts ...
Designing and Delivering Dementia Services
Dementia is increasingly and widely recognised as a serious health and social challenge, in the developed world as well as in the developing world. The need therefore to design and implement dementia care services of high quality is becoming more and more vital, particularly given the likelihood of ever increasing demand in a world, which likely sees resources at best remaining at current levels. Designing and Delivering Dementia Services describes current developments in the design and configuration of dementia services. It offers an informative and detailed overview of what constitutes high quality care, considering the circumstances patients and carers may find themselves in. For dementia...
