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Modular construction can dramatically improve efficiency in construction, through factory production of pre-engineered building units and their delivery to the site either as entire buildings or as substantial elements. The required technology and application are developing rapidly, but design is still in its infancy. Good design requires a knowledge of modular production, installation and interface issues and also an understanding of the economics and client-related benefits which influence design decisions. Looking at eight recent projects, along with background information, this guide gives you coverage of: generic types of module and their application vertical loading, stability and robustness dimensional and spacial planning hybrid construction cladding, services and building physics fire safety and thermal and acoustic performance logistical aspects – such as transport, tolerances and safe installation. A valuable guide for professionals and a thorough introduction for advanced students.
Topics covered within this set of conference proceedings include: structural analysis - theory and methods; structural design - concept, technique and codes of practice; structural forms - concept and application; and construction of structures.
Lactic Acid Bacteria Biodiversity and Taxonomy Lactic Acid Bacteria Biodiversity and Taxonomy Edited by Wilhelm H. Holzapfel and Brian J.B. Wood The lactic acid bacteria (LAB) are a group of related microorganisms that are enormously important in the food and beverage industries. Generally regarded as safe for human consumption (and, in the case of probiotics, positively beneficial to human health), the LAB have been used for centuries, and continue to be used worldwide on an industrial scale, in food fermentation processes, including yoghurt, cheeses, fermented meats and vegetables, where they ferment carbohydrates in the foods, producing lactic acid and creating an environment unsuitable f...
Therapeutic breakthroughs in medicine are usually accompanied by a wealth of data. Often they result in a change of disease treatment paradigms. Tacrolimus ointment is the first in the new class of steroid-free Topical Immunomodulators (TIMs), and as such represents the first true breakthrough since the introduction of topical steroids more than 50 years ago for the treatment of T-cell mediated inflammatory skin diseases such as atopic dermatitis. This book gives an easy-to-read overview of the discovery and the development of Tacrolimus ointment for the treatment of atopic dermatitis. Summarising the largest clinical trial program ever conducted in dermatology for a new treatment with more than 13000 patients, it offers a detailed insight into the efficacy and safety profile of Tacrolimus ointment. Based on this large body of data and extensive personal experience, the authors offer practical and hands-on guidance for the physician as to when and how to use Tacrolimus ointment in daily practice.