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On December 18, 1867, the Buffalo and Erie Railroad’s eastbound New York Express derailed as it approached the high truss bridge over Big Sister Creek, just east of the small settlement of Angola, New York, on the shores of Lake Erie. The last two cars of the express train were pitched completely off the tracks and plummeted into the creek bed below. When they struck bottom, one of the wrecked cars was immediately engulfed in flames as the heating stoves in the coach spilled out coals and ignited its wooden timbers. The other car was badly smashed. About fifty people died at the bottom of the gorge or shortly thereafter, and dozens more were injured. Rescuers from the small rural community...
My lifetime encompasses the postwar subsidence in the early 1920s of the greatest influenza pandemic in history, direct encounters with FM1 virus at Fort Mon mouth in 1947, the care of influenza patients in the 1950s, the pursuit of the in fluenza virus through the modern pandemics of 1957 and 1968, and a present in which the genes of the virus have dissembled in the DNA of vaccinia virus and Escherichia coli through the wand of "high tech. " If my corpus could be fossilized for archival and archaeological purposes, it would be found to contain immune cells branded with the imprint of the "swine" influenza virus of post-1918 and brain cells no less imprinted with memories of the abortive ret...
Now in its thoroughly revised, updated Fifth Edition, this handbook is a practical, easily accessible, and authoritative guide to the diagnosis and treatment of infectious diseases. Leading experts present realistic clinical approaches to infectious disease problems seen in hospital and outpatient settings and offer up-to-the-minute advice on antimicrobial use--including specific recommendations on dosages, routes of administration, and duration of therapy. Chapters are written in a user-friendly outline format that is ideal for quick reference.This edition includes complete information on new diseases, new antibiotics, and HIV antiviral agents.