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Diagnosis of Blood and Bone Marrow Disorders
This book focuses on hematopoietic and lymphoid neoplasms that initially present as peripheral blood abnormalities, with either cytopenias or elevated peripheral blood counts, as well as non-neoplastic conditions that may raise concern for a hematologic malignancy. The scope of the book includes myelodysplastic syndromes (MDS), myeloproliferative neoplasms (MPN), mixed myelodysplastic/myeloproliferative neoplasms (MDS/MPN), as well as lymphomas and lymphoid leukemias that typically present initially with peripheral blood abnormalities. Within each category, a comprehensive list of differential diagnoses is discussed. For each disease entity, the reader is updated with new molecular genetic d...
Diagnostic Pathology of Infectious Disease E-Book
Comprehensive and up to date, the Second Edition of Diagnostic Pathology: Infectious Disease, by Dr. Richard Kradin, is an invaluable tool for the accurate diagnosis of any infectious disease―from the common to the most challenging. The organ-based format makes it an especially useful tool for surgical pathologists' daily diagnostic and management issues. High-quality, full-color illustrations and differential diagnosis tables accompany each lesion, clearly depicting how to recognize the morphology of organisms and the spectrum of histological responses that they may cause. - Addresses the most difficult diagnostic issues that practicing or trainee surgical pathologists face when handling ...
Neoplastic Hematopathology
Neoplastic Hematopathology provides a concise, visual approach to guide practicing pathologists, hematopathologists, hematologists, oncologists, internists, and trainees to a clear analysis and diagnosis of myeloid and lymphoid specimens. Coverage is comprehensive and for each entity includes a short text description of the key points of the entity- definition; morphologic features; special stains, immunohistochemistry and flow cytometry techniques; differential diagnosis; diagnostic features; special issues (e.g., prognostic or other considerations to note). Images in Neoplastic Hematopathology highlight differential diagnostic features, especially the correlation and integration of standar...
Neoplastic Hematopathology
Fulfilling the void with a Hematopathology book that integrates clinical and experimental studies with diagnostic criteria, Neoplastic Hematopathology: Experimental and Clinical Approaches provides an overview of the discipline of hematopathology that connects the field with recent advances in immunology research and current clinical practice in the treatment of lymphomas and leukemias. Designed for both trainees and specialists in pathology and hematology-oncology, Neoplastic Hematopathology: Experimental and Clinical Approaches has separate sections on laboratory techniques, diagnostic hematopathology, treatment and stem cell transplantation. Expert chapter authors address both myeloid and lymphoid tumors, and provide much needed coverage in transplant biology. A study guide highlights key chapter points, making the text suitable for boards review in hematopathology and hematology-oncology.
Diagnosis and Management of Myelodysplastic Syndromes
Myelodysplastic syndromes (MDS) are a group of clonal disorders characterized by pancytopenias and the risk of progression to acute myeloid leukemia. The diagnosis of MDS can be challenging, while the outcomes of MDS patients vary widely. This book provides a concise yet comprehensive overview of MDS. The book begins by reviewing the diagnostic workup of MDS, with a specific focus on the 2016 WHO criteria for MDS diagnosis, and the biology and pathophysiology of the disease. The text then presents the molecular landscape of MDS and its impact on disease diagnosis, prognosis, and treatment decisions. The book continues by profiling different prognostic models of MDS and concludes with a thorough review of treatment algorithms for lower and higher-risk MDS, as well as the use of hematopoietic stem cell transplant to combat the disease. Written by experts in the field, Diagnosis and Management of Myelodysplastic Syndromes: A Clinical Guide is a valuable resource for clinicians, practitioners, and researchers who are interested in MDS. The text also features over 100 illustrations, photographs, and tables.
Hematologic Malignancies
Authoritative reviews and updates discuss recent advances in radiation therapy in treatment of Hodgkins lymphoma, B-cell nodal and extranodal lymphomas, follicular lymphoma and cutaneous T-cell lymphoma; mantle cell lymphoma, and leukemia. In addition, reviews of current developments in PET imaging in lymphoma, radioimmunotherapy, and radiation and transplant, are included. This volume of Radiation Medicine Rounds gives the radiation oncology professional a complete overview of current best practice and emerging modalities for radiation treatment of hematologic malignancies.Hematologic Maligna.
Hematopathology, An Issue of Surgical Pathology Clinics
Dr. George Fedoriw leads the second issue presented in the Surgical Pathology Clinics on Hematopathology. Topics in this issue include: Evidence-based, high-value hematopathology; The expanding spectrum of follicular lymphoma; Lymphoid proliferations in the immunocompromised host; Reporting clinically relevant biomarkers of intermediate/high grade B-cell lymphomas; Transformation of lymphomas; T-cell lymphoproliferations: distinguishing benign from malignant; Lymphoma microenvironment and immunotherapy; Differentiating low grade lymphomas with non-specific immunophenotype; Molecular markers of myeloid leukemias and myelodysplastic syndromes; Update of myeloproliferative neoplasms; Mimics of myeloid neoplasms; Therapy effect: impact on bone marrow morphology. Each topic is written by a leader in pathology with expertise in hematopathology. The focus on these articles, as all in the series, is on Differential Diagnosis, with histologic images and tips for working with the most challenging aspects of these pathologies.
Robbins and Cotran Review of Pathology
Effectively master the most important principles and facts in pathology with this easy-to-use new edition of Robbins and Cotran Review of Pathology. More than 1,100 questions-reviewed and updated to reflect the new content in the parent text-reinforce the fundamentals of gross and microscopic pathology as well as the latest findings in molecular biology and genetics. This review book of multiple choice questions and answers, companion to Robbins and Cotran Pathologic Basis of Disease 9th Edition and Robbins Basic Pathology, 9th Edition, is the ideal study tool for coursework, self-assessment, and examinations, including the USMLE Step 1 examination in pathology. Access to this product, which...
Diffuse Large B Cell Lymphoma: Updates on Diagnosis and Treatments
Diffuse Large B Cell Lymphoma (DLBCL) is the most common Non-Hodgkin Lymphoma in Western countries and is comprised of a heterogeneous group of biologically distinct entities resulting in the clonal proliferation of a germinal or post-germinal malignant B cell. The disease is particularly aggressive with 40% of the afflicted individuals succumbing to the disease. The standard treatment for DLBCL is still chemo-immunotherapy with R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone). Whilst this modality is safe and effective, up to 45%–50% of patients will relapse. Despite advances in therapy, DLBCL remains a challenging disease to manage, with significant heterogeneity in clinical presentation and outcomes. Therefore, there is a need to update the medical community with the latest updates in the diagnosis and treatment of DLBCL.
Extranodal Lymphomas
Dr. Judith Ferry and leaders in the field present their expertise to fill the need for a highly-illustrated, authoritative reference that keeps you up to date on histologic, immunophenotypic, genetic, and clinical features, along with risk factors and current nomenclature. Effectively diagnose both extranodal and intranodal lymphomas using comprehensive coverage. Quickly find pathologic criteria with chapters organized by anatomic site providing a comprehensive list of extranodal sites, including the central nervous system, the head and neck, heart, lungs, gastrointestinal tract, skin, bone, bone marrow, and more. The definitive textbook on extranodal lymphomas, written by experts in the field of Hematopathology.
