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The Metabolic-Inflammatory Axis in Brain Aging and Neurodegeneration
Impairment of energy metabolism is a hallmark of brain aging and several neurodegenerative diseases, such as the Alzheimer’s disease (AD). Age- and disease-related hypometabolism is commonly associated with oxidative stress and they are both regarded as major contributors to the decline in synaptic plasticity and cognition. Neuroinflammatory changes, entailing microglial activation and elevated expression of inflammatory cytokines, also correlate with age-related cognitive decline. It is still under debate whether the mitochondrial dysfunction-induced metabolic deficits or the microglia activation-mediated neuroinflammation is the initiator of the cognitive changes in aging and AD. Neverth...
Explorations
Welcome to Explorations and biological anthropology! An electronic version of this textbook is available free of charge at the Society for Anthropology in Community Colleges' webpage here: www.explorations.americananthro.org
Emerging Drugs and Targets for Alzheimer's Disease
This volume describes the discovery and development history of promising drugs now in development for combating Alzheimer's disease.
Transportation Systems Analysis
"This book provides a rigorous and comprehensive coverage of transportation models and planning methods and is a must-have to anyone in the transportation community, including students, teachers, and practitioners." Moshe Ben-Akiva, Massachusetts Institute of Technology.
Vegolosi MAG #28
Vegolosi MAG è il mensile digitale per chi vuole imparare a cucinare 100% vegetale senza nessuna rinuncia e in modo facile grazie alle ricette della chef Sonia Maccagnola; un giornale per chi vuole informarsi sul mondo che cambia con inchieste, interviste e approfondimenti realizzati dalla nostra redazione con esperienza decennale su questi temi. Il mensile ti propone solo contenuti esclusivi che non vengono pubblicati online. Nel numero di novembre trovi: RICETTE: 20 idee facili, originali e inedite (non le troverai mai su Vegolosi.it) create dalla nostra chef Sonia Maccagnola INTERVISTE: mangiare non è così “semplice” come sembra. Scopriamo insieme alla dottoressa Teresa Montesarchi...
Systematic Reviews in the Social Sciences
Such diverse thinkers as Lao-Tze, Confucius, and U.S. Defense Secretary Donald Rumsfeld have all pointed out that we need to be able to tell the difference between real and assumed knowledge. The systematic review is a scientific tool that can help with this difficult task. It can help, for example, with appraising, summarising, and communicating the results and implications of otherwise unmanageable quantities of data. This book, written by two highly-respected social scientists, provides an overview of systematic literature review methods: Outlining the rationale and methods of systematic reviews; Giving worked examples from social science and other fields; Applying the practice to all soc...
Vegolosi MAG #29
Vegolosi MAG è il mensile digitale per chi vuole imparare a cucinare 100% vegetale senza nessuna rinuncia e in modo facile grazie alle ricette della chef Sonia Maccagnola; un giornale per chi vuole informarsi sul mondo che cambia con inchieste, interviste e approfondimenti realizzati dalla nostra redazione con esperienza decennale su questi temi. Il mensile ti propone solo contenuti esclusivi che non vengono pubblicati online. Nel numero di dicembre trovi: RICETTE: 20 idee facili, originali e inedite (non le troverai mai su Vegolosi.it) create dalla nostra chef Sonia Maccagnola MENU DI NATALE 2022: 4 ricette imperdibili e inedite per un Natale 100% vegetale da tripudio! INTERVISTE: orientar...
Waste
With shortages, volatile prices and nearly one billion people hungry, the world has a food problem � or thinks it does. Farmers, manufacturers, supermarkets and consumers in North America and Europe discard up to half of their food � enough to feed all the world�s hungry at least three times over. Forests are destroyed and nearly one tenth of the West�s greenhouse gas emissions are released growing food that will never be eaten. While affluent nations throw away food through neglect, in the developing world crops rot because farmers lack the means to process, store and transport them to market. But there could be surprisingly painless remedies for what has become one of the world�s most pressing environmental and social problems. Travelling from Yorkshire to China, from Pakistan to Japan, and introducing us to foraging pigs, potato farmers, freegans and food industry directors, Stuart encounters grotesque examples of profligacy, but also inspiring innovations and ways of making the most of what we have. Combining front-line investigation with startling new data, Waste shows how the way we live now has created a global food crisis � and what we can do to fix it.
