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Essa obra possui um viés duplo que trabalha eixos sobre o arquétipo da sustentabilidade contemporânea. Englobando, portanto, os desafios provenientes do desenvolvimento econômico e social sob o manto da sustentabilidade, bem como aborda questões provenientes dos anseios democráticos fundados numa perspectiva participativa e plural.
Guanine rich DNA has been known for decades to form unusual structures, although their biological relevance was little understood. Recent advances have demonstrated that quadruplex structures can play a role in gene expression and provide opportunities for a new class of anticancer therapeutics. A number of quadruplex-specific proteins have also been discovered. Quadruplex Nucleic Acids discusses all aspects of the fundamentals of quadruplex structures, including their structure in solution and the crystalline state, the kinetics of quadruplex folding, and the role of cations in structure and stability. The biology of quadruplexes and G-rich genomic regions and G-quartets in supramolecular chemistry and nanoscience are also considered. Surveying the current state of knowledge, and with contributions from leading experts, this is the first comprehensive review of this rapidly growing area. Quadruplex Nucleic Acids is ideal for researchers interested in areas related to chemistry, chemical biology, medicinal chemistry, molecular pharmacology, and structural and molecular biology.
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One Hundred Twentieth-Century Philosophers offers biographical information and critical analysis of the life, work and impact of some of the most significant figures in philosophy this century. Taken from the acclaimed Biographical Dictionary of Twentieth-Century Philosophers, the 100 entries are alphabetically organised, from Adorno to Zhang Binglin, and cover individuals from both continental and analytic philosophy. The entries have an identical four-part structure making it easy to compare and contrast information, comprising: * biographical details * a bibliography of major works * a listing of relevant secondary and critical literature * an appraisal of the philosopher's thoughts and achievements. A separate glossary provides an introduction to the origins, development and main features of major philosophical schools and movements and offers select bibliographies to guide the reader to further research.
Hoofdstukken over kunstenaars en kunstuitingen vormen het uitgangspunt van deze Studie over de relatie tussen avant-garde kunst en de massacultuur
"This richly illustrated and designed book in the "Architecture in Focus" series reconsiders critical regionalism and demonstrates the global viability of one of the most visible trends in contemporary architecture. As globalization increasingly enters every facet of our lives, its homogenizing effects on architecture, urban spaces and the landscape have compelled architects to embrace the principles of critical regionalism, an alternative theory that respects local culture, geography and climate. In this reexamination of critical regionalism, two prominent architectural critics argue for a truce between the seemingly antithetical philosophies of critical regionalism and globalization. The a...
The definitive introductory book on the theory and history of regionalist architecture in the context of globalization, this text addresses issues of identity, community, and sustainability along with a selection of the most outstanding examples of design from all over the world. Alex Tzonis and Liane Lefaivre give a readable, vivid, scholarly account of this major conflict as it relates to the design of the human-made environment. Demystifying the reasons behind how globalization enabled creativity and brought about unprecedented wealth but also produced new wastefulness and ecological destruction, the book also looks at how regionalism has also tended to confine, tearing apart societies and promoting destructive consumerist tourism.
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The EU has been portrayed as a leader in international climate change negotiations. Its role in the development of the climate change regime, as well as the adoption of novel policy instruments such as the EU Emissions Trading Scheme in 2005, are frequently put forward as indicative of a determination to push the international climate agenda forward. However, there are numerous instances where the EU has failed to achieve its climate change objectives (e.g. the 2009 Copenhagen Conference of the Parties). It is therefore important to examine the reasons behind these failures. This book explores in detail the involvement of the EU in international climate talks from the late 1980s to the prese...