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Chemistry Department At Imperial College London, The: A History, 1845-2000
This is the first comprehensive history of the chemistry department at Imperial College London. Based on archival records, oral testimony, published papers, published and unpublished memoirs, the book tells the story of this world-famous department from its foundation as the Royal College of Chemistry in 1845 to the large department it had become by the year 2000.The book covers research, teaching, departmental governance, students and social life. It also highlights the extraordinary contributions made to the war effort in both the first and second world wars. From its first professors, A. Wilhelm Hofmann and Edward Frankland, the department has been home to many eminent chemists, including, in the later twentieth century, the Nobel laureates Derek Barton and Geoffrey Wilkinson. New information on these and many others is presented in a lively narrative that places both people and events in the larger historical contexts of chemistry, politics, culture and the economy. The book will interest not only those connected with Imperial College, but anyone interested in chemistry and its history, or in higher
Comprehensive Analysis of Parasite Biology
Written and edited by experts in the field, this book brings together the current state of the art in phenotypic and rational, target-based approaches to drug discovery against pathogenic protozoa. The chapters focus particularly on virtual compounds and high throughput screening, natural products, computer-assisted drug design, structure-based drug design, mechanism of action identification, and pathway modelling. Furthermore, state-of the art "omics" technologies are described and currently studied enzymatic drug targets are discussed. Mathematical, systems biology-based approaches are introduced as new methodologies for dissecting complex aspects of pathogen survival mechanisms and for target identification. In addition, recently developed anti-parasitic agents targeting particular pathways, which serve as lead compounds for further drug development, are presented.
History Of Imperial College London, 1907-2007, The: Higher Education And Research In Science, Technology And Medicine
This is the first major history of Imperial College London. The book tells the story of a new type of institution that came into being in 1907 with the federation of three older colleges. Imperial College was founded by the state for advanced university-level training in science and technology, and for the promotion of research in support of industry throughout the British Empire. True to its name the college built a wide number of Imperial links and was an outward looking institution from the start. Today, in the post-colonial world, it retains its outward-looking stance, both in its many international research connections, and with staff and students from around the world. Connections to industry and the state remain important. The College is one of Britain's premier research and teaching institutions, including now medicine alongside science and engineering. This book is an in-depth study of Imperial College; it covers both governance and academic activity within the larger context of political, economic and socio-cultural life in twentieth-century Britain./a
Enzymes as Catalysts in Organic Synthesis
Proceedings of the NATO Advanced Research Workshop, Reisensburg/Ulm, Donau, Germany, June 16-22, 1985
Peptides: The Wave of the Future
This volume contains the proceedings of the Second International Peptide Symposium and the Seventeenth American Peptide Symposium, held on 9-14 June, 2001, at the Town and Country Resort in San Diego, California. The biennial meeting was held under the auspices of the American Peptide Society. In addition to the main Symposium, we were honored to have the Merrifield Satellite Symposium, honoring Bruce Merrifield's accomplishments on his 80th birthday. Over 1250 participants from around the world attended the lectures, posters, and exhibits. Reflecting the international nature of the Symposium, there were participants from 37 countries in attendance. In addition to the 75 plenary lectures, there were over 575 poster presentations, and 70 commercial exhibits as well as booths from the American, Australian, Chinese, European, and Japanese Peptide Societies. These proceedings include plenary lectures and oral and poster presentations collected from a wide diversity of topics providing a truly comprehensive and up-to-date overview of the field of peptide science. This publication contains essential reference information for researchers active in peptide science.
Computational Aspects of the Study of Biological Macromolecules by Nuclear Magnetic Resonance Spectroscopy
This volume is the scientific chronicle of the NATO Advanced Research Workshop on Computational Aspects of the Study of Biological Macro molecules by Nuclear Magnetic Resonance Spectroscopy, which was held June 3-8, 1990 at Il Ciocco, near Barga, Italy. The use of computers in the study of biological macromolecules by NMR spectroscopy is ubiquitous. The applications are diverse, including data col lection, reduction, and analysis. Furthermore, their use is rapidly evolv ing, driven by the development of new experimental methods in NMR and molecular biology and by phenomenal increases in computational perfor mance available at reasonable cost. Computers no longer merely facilitate, but are now absolutely essential in the study of biological macromolecules by NMR, due to the size and complexity of the data sets that are obtained from modern experiments. The Workshop, and this proceedings volume, provide a snapshot of the uses of computers in the NMR of biomolecules. While by no means exhaustive, the picture that emerges illustrates both the· importance and the diversity of their application.
