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Thoroughly examining the popular and expanding field of reproductive toxicology, this newly revised and expanded third edition provides the latest, cutting-edge scientific developments in this constantly evolving discipline. Reproductive Toxicology’s contributors are experienced regulatory agency and Clinical Research Organization representatives who currently utilize the new techniques discussed in the text and continue to revolutionize reproductive toxicology research. This ground-breaking resource includes: New and important critical mechanistic topics such as epigenetics and omics The first significant compilation of epigenetic mechanisms An in-depth analysis of the role of genomics, proteomics, and metabolomicsin human reproduction New guidelines with respect to the latest research applications in the field
Developmental toxicology, an increasingly important area, encompasses the study of toxicant effects on development, from conception through puberty. The Handbook of Developmental Toxicology provides useful insights gained from hands-on experience, as well as a theoretical foundation. In this convenient reference you will find information not previously gathered in one source-including comparative developmental milestones, historical data, and a glossary of terms used in developmental toxicity evaluation. This handbook is a practical guide for individuals who are responsible for testing chemical agents and for regulatory scientists who must evaluate studies, interpret data, and perform risk assessments. Packed with features, the Handbook of Developmental Toxicology is ideal for training students and technicians in developmental toxicology.
Clinical & Experimental Toxicology of Organophosphates and Carbamates considers the histochemical localization of cholinesterase in anticholinesterase poisoning. This book is organized into eight parts encompassing 59 chapters that discuss the pharmacology and toxicology of carbamates, as well as the neurobehavioral toxicology of anticholinesterases. Some of the topics covered in the book are the overview of biological and clinical aspects of organophosphates and carbamates; biochemical determination of cholinesterase activity in fluids and tissues; intermediate syndrome in anticholinesterase neurotoxicity; structure-activity relationships and anticholinesterase activity; and the molecular e...
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Completely revised and updated, Developmental and Reproductive Toxicology: A Practical Approach, Second Edition draws together valuable information typically scattered throughout the literature, plus some not previously published, into one complete resource. In addition to the traditional aspects of developmental toxicity testing, the book covers e
Witnesses: Jeff Byron; Mike Gros; Jerome Ensminger; Robert Dickerson, Jr., Command. Gen., Camp Lejeune, NC; Kelly Dreyer, Environ. Restoration Program Mgr., U.S. Marine Corps; Pat Leonard, Office of the Judge Advocate Gen., Claims, Invest., and Tort Litigation; Thomas Sinks, deputy dir., Nat. Center of Environmental Health, Agency for Toxic Substances and Disease Registry (ATSDR), accomp. by Frank Bove, Sr. epidemiologist, ATSDR, and Morris Maslia, environmental engineer, ATSDR; Peter Murtha, Dir., Office of Criminal Enforcement, Forensics and Training, Office of Enforcement and Compliance Assurance, EPA; Marcia Crosse, Dir., Public Health and Military Health Care Issues, GAO; Franklin Hill, Superfund Div., EPA. Illustrations.
Perspectives in Basic and Applied Toxicology features a collection of essays on various aspects of toxicology. It aims to relate fundamental knowledge of toxicology to its application in assessing relevance of that information to the causation of adverse health effects, predicting hazardous situations, defining protective and precautionary measures, and the recognition and management of intoxication in humans. Another objective of this volume is to encourage those with responsibility for the training of toxicologists to instill a greater concern about ethical and moral issues as fundamental to the practice of toxicology as a profession with wide-ranging social implications. This book is organized into 14 chapters. The coverage of these chapters include assessment of chemical hazards in the workplace, the relation between animal studies and epidemiology in the context of industrial toxicology, carcinogenicity testing in animals, and biochemical evaluation of neurotoxicity. This book will be of interest to undergraduate and graduate toxicologists, pharmacologists, physicians, industrial hygienists, and other health professionals.
Papers from an October 1993 conference chart recent changes in US courts and the judicial system and suggest reforms for the problems these changes present. Sections survey pre-trial and the dynamics of settlement, trial and the role of science in the courts, and post-trial and the need to control jury decision making. Discussion includes areas such as settlement incentives, guiding jurors in valuing pain and suffering damages, and the treatment of scientific evidence after Daubert v. Merrell Dow. For judges, lawyers, and other law professionals. Annotation copyright by Book News, Inc., Portland, OR