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CRISPR
“An excellent compendium of all things CRISPR from some of the leading minds in the field. With thorough coverage from every angle and beautifully detailed illustrations, this book is not to be missed!” Jennifer A. Doudna, Professor of Chemistry, Biochemistry & Molecular Biology, UC Berkeley; Founder, Innovative Genomics Institute; Nobel Laureate and coinventor of CRISPR technology “This journey through CRISPR biology and several of its breakthrough applications offers an exciting glimpse into one of the most beautiful and compelling fields in the life sciences.” David R. Liu, Director of the Merkin Institute at the Broad Institute of MIT and Harvard; Professor of Chemistry and Chemi...
The Code Breaker -- Young Readers Edition
Walter Isaacson’s #1 New York Times bestselling history of our third scientific revolution: CRISPR, gene editing, and the quest to understand the code of life itself, is now adapted for young readers! When Jennifer Doudna was a sixth grader in Hilo, Hawaii, she came home from school one afternoon and found a book on her bed. It was The Double Helix, James Watson’s account of how he and Francis Crick had discovered the structure of DNA, the spiral-staircase molecule that carries the genetic instruction code for all forms of life. This book guided Jennifer Doudna to focus her studies not on DNA, but on what seemed to take a backseat in biochemistry: figuring out the structure of RNA, a clo...
CRISPR-Cas Systems
CRISPR/Cas is a recently described defense system that protects bacteria and archaea against invasion by mobile genetic elements such as viruses and plasmids. A wide spectrum of distinct CRISPR/Cas systems has been identified in at least half of the available prokaryotic genomes. On-going structural and functional analyses have resulted in a far greater insight into the functions and possible applications of these systems, although many secrets remain to be discovered. In this book, experts summarize the state of the art in this exciting field.
The Good Virus: The Amazing Story and Forgotten Promise of the Phage
A New York Times Editors’ Choice “A deft narrative that is rich and approachable.” —Alex Johnson, New York Times Book Review How a mysterious, super-powerful—yet long-neglected—microbe rules our world and can rescue our health in the age of antibiotic resistance. At every moment, within our bodies and all around us, trillions of microscopic combatants are waging a war that shapes our health and life on Earth. Countless times per second, viruses known as phages attack and destroy bacteria while leaving all other life forms, including us, unscathed. Vastly outnumbering the viruses that do us harm, phages power ecosystems, drive evolutionary innovation, and harbor a remarkable capac...
Bifidobacteria and Their Role in the Human Gut Microbiota. 2nd Edition
The human intestine is home of an almost inconceivable large number of microorganisms. The human gut microbiota can therefore be pictured as an organ placed within a host organism. The human gut microbiome, which in total may contain >100 times the number of genes present in our genome, endows us with functional features that we did not have to evolve ourselves. It is recognized that intestinal microbiota plays an important role in human health and disease. In fact, gut bacteria other than metabolize dietary components, may play complex roles such as modulation of the immune system and in reduction of gut infections. Variations in the presence and/or abundance of certain components of the in...
Next: A Brief History of the Future
13 game-changing innovations that will transform the world An in-depth look at how science, technology, innovation, and development is poised to change our destiny Star Trek–loving inventors who 3D print in space, vegan researchers who replicate the composition and chemical structures of meat in a lab, and mad scientists who save humans from terrible disorders by cutting and pasting genes like letters in a document. These are a few of the remarkable stories featured in Next, an in-depth look at the coming global challenges and the transformative innovations that will help make our world a better place. Next tells the story of 13 inspiring innovators around the world who are already tackling these challenges and transforming our species. Call it Humanity 2.0. Every individual and venture featured in Next is having an outsized impact on human history. Their stories show what the future might look like. But most of all, they will give readers hope. As the science fiction writer William Gibson once put it: “The future is already here. It is just not very evenly distributed.”
Global Health Security
With lessons learned from COVID-19, a world-leading expert on pandemic preparedness proposes a pragmatic plan urgently needed for the future of global health security. The COVID-19 pandemic revealed how unprepared the world was for such an event, as even the most sophisticated public health systems failed to cope. We must have far more investment and preparation, along with better detection, warning, and coordination within and across national boundaries. In an age of global pandemics, no country can achieve public health on its own. Health security planning is paramount. Lawrence O. Gostin has spent three decades designing resilient health systems and governance that take account of our int...
The Future of Food
The destiny of humans is parallel to the destiny of food. If the latter is available, then the former will also be present. The definition of food today is very different from that of our ancestors, who saw it as a nutritious thing that may obtainable through collecting or planting. However, today, food can be modified genetically and made through molecular synthesis. This book discusses the future of food, and explores the context of novel definitions of food through horizon scanning. It considers the most cutting-edge developments in the food industry, including lab-meat, nano-engineered foods, vertical agriculture, foodomics, and Marsfoods. The book also investigates new food engineering processing techniques, future technologies, and future consumption trends.
Microbiology
Microbiology is a comprehensive textbook that facilitates a thorough understanding of the scope, nature, and complexity of the science of microscopic organisms. It gives a balanced presentation of foundational concepts, real-world applications, and current research and experimentation. The text approaches the subject within the context of exploration and experimentation, integrating a wealth of classroom-tested pedagogical features. The material is organized around the three pillars of physiology, ecology, and genetics -- helping students appreciate the interconnected and dynamic nature of microbiology and explore the relationship between different types of microbes, other organisms, and the...
