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50 Studies Every Neonatologist Should Know
50 Studies Every Neonatologist Should Know presents a selection of seminal trials in neonatology, including both cornerstones of practice and frontiers in trial design. The included trials cover a broad range of care topics in neonatology, as well as important learning points in a number of dimensions. The text explores each trial in a dedicated chapter, with a concise summary of methods and results, accompanied by a brief discussion of special considerations, including risks of bias, interpretation, and implications for practice. Additionally, there is a short interview with the trialist (or an editorial commentary) at the end of each chapter, to give a flavor of the ongoing conversation after trial publication. As with all books in the "50 Studies" series, each study was selected using an objective selection criterion that included citations per year, high levels of evidence, clinical studies and trials, and a 3-stage Delphi review by international experts in the field. It is a must-read for neonatologists, trainees, or anyone involved in neonatal care or trial design.
New Therapies for Neonatal Respiratory Failure
The diagnosis and treatment of respiratory problems in the newborn have advanced significantly over recent years, although respiratory failure remains an important cause of neonatal mortality and morbidity. This book provides a comprehensive overview of respiratory physiology in the newborn, and of the mechanism underlying respiratory failure in this age group. It goes on to present in detail the techniques, both novel and well established, for effective ventilatory support. In presenting and evaluating the available treatment modalities, the authors consider not only clinical indications, modes of delivery and monitoring, but also complications and outcomes. Comprehensive and up to date, this is an essential handbook and reference for clinicians in neonatal medicine, that will help to optimise their management of respiratory failure in the newborn.
New Developments in Blood Transfusion Research
Although blood transfusion saves lives and reduces morbidities in many clinical diseases and conditions, it is associated with certain risks. A transfusion-related adverse event, also called transfusion reaction, is any unfavourable event occurring in a patient during or after blood transfusion. About 0.5 per cent to 3 per cent of all transfusions result in some adverse events, but the majority of them are minor reactions with no significant consequences. In general, transfusion-related adverse events are categorised as infectious and non-infectious. However, there are other classifications in the literature based on time of occurrence (i.e. acute versus delayed) or physiological mechanism (i.e. immune mediated versus non-immune mediated). A significant proportion of adverse events may occur as a result of errors in preparation, ordering or administration of blood and blood products. This book contains the latest research in this essential field which has been revolutionised in recent decades.
Assisted Ventilation of the Neonate
Assisted Ventilation of the Neonate, 5th Edition, by Drs. Jay P. Goldsmith and Edward Karotkin, guides you through the latest innovations in ventilatory assistance, helping you improve outcomes and quality of life in newborns. With a new emphasis on non-invasive ventilation and earlier extubation, it covers basic concepts of pulmonary pathophysiology and offers practical guidance on both basic and advanced ventilation management strategies. Access expert coverage of all aspects of neonatal pulmonary care—including complications, nutrition, transport, outcomes, follow-up, and parental education. Sharpen your diagnostic and clinical skills with case studies drawn from actual patients. Find k...
Advances in Respiratory Care of the Newborn, An Issue of Clinics in Perinatology - E-Book
Top authors were selected to write clinical review articles devoted to Advances in Respiratory Care of the Newborn. Articles are devoted to: Effects of chorioamnionitis on lung function and growth; Delivery room respiratory management of the term and preterm infant; CPAP or INSURE for initial respiratory support; Which CPAP is best?; Non-invasive respiratory support; Volume limited and volume targeted ventilation; Weaning from mechanical ventilation; Predictors of bronchopulmonary dysplasia; Brain Injury in Chronically Ventilated Preterm Neonates: Collateral Damage Related to Ventilation Strategy; The Pulmonary Circulation in Respiratory Failure; Novel methods for assessment of right heart structure and function in pulmonary hypertension; Control of oxygenation; Non-invasive monitoring by photoplethysmography; Cell-based strategies to reconstitute lung function in infants with severe bronchopulmonary dysplasia; Permissive Hypercapnea; Prevention of BPD with Nitric Oxide; and Aero-digestive pulmonary disorders in the neonate.
Spina Bifida
The aim of this book to promote a multidisciplinary approach to Spina Bifida, providing the three main specialists categories involved – neurosurgeon, orthopedic surgeons, and urologists – with a concise reference that explains the main clinical problems to be faced in everyday clinical practice. The book also provides the busy specialist with an updated overview of surgical approaches.
Goldsmith's Assisted Ventilation of the Neonate - E-Book
A must-have reference for the entire NICU, Goldsmith's Assisted Ventilation of the Neonate, 7th Edition, is the only fully comprehensive, evidence-based guide to all aspects of this fast-changing field. Easy to use and multidisciplinary in scope, this trusted reference provides authoritative guidance on contemporary management of neonatal respiratory diseases, with an emphasis on evidence-based pharmacologic and technologic advances that improve outcomes and quality of life in newborns. It's an outstanding resource for neonatologists and NICU professionals to acquire new knowledge and techniques in this critical area of neonatal care. - Covers all aspects of both basic and advanced respirato...
Physician-Assisted Death in Perspective
This book is the first comprehensive report and analysis of the Dutch euthanasia experience over the last three decades. In contrast to most books about euthanasia, which are written by authors from countries where the practice is illegal and therefore practiced only secretly, this book analyzes empirical data and real-life clinical behavior. Its essays were written by the leading Dutch scholars and clinicians who shaped euthanasia policy and who have studied, evaluated, and helped regulate it. Some of them have themselves practiced euthanasia. The book will contribute to the world literature on physician-assisted death by providing a comprehensive examination of how euthanasia has been practiced and how it has evolved in one specific national and cultural context. It will greatly advance the understanding of euthanasia among both advocates and opponents of the practice.
Pediatric and Neonatal Mechanical Ventilation
Written by outstanding authorities from all over the world, this comprehensive new textbook on pediatric and neonatal ventilation puts the focus on the effective delivery of respiratory support to children, infants and newborns. In the early chapters, developmental issues concerning the respiratory system are considered, physiological and mechanical principles are introduced and airway management and conventional and alternative ventilation techniques are discussed. Thereafter, the rational use of mechanical ventilation in various pediatric and neonatal pathologies is explained, with the emphasis on a practical step-by-step approach. Respiratory monitoring and safety issues in ventilated patients are considered in detail, and many other topics of interest to the bedside clinician are covered, including the ethics of withdrawal of respiratory support and educational issues. Throughout, the text is complemented by numerous illustrations and key information is clearly summarized in tables and lists.
Quality Improvement in Neonatal and Perinatal Medicine, An Issue of Clinics in Perinatology
This issue of Clinics in Perinatology, guest edited by Drs. Alan Spitzer and Dan Ellsbury, examines Quality Improvement in Neonatal and Perinatal Medicine. The first part of the issue addresses Tools of Quality Improvement and includes articles on The Quality Chasm in Neonatal and Perinatal Medicine; Evaluating the Medical Evidence; The Vermont Oxford Network Database; The Pediatrix Clinical Data Warehouse; Role of Regional Collaboratives: The California Perinatal Quality Care Collaborative Model; A Primer on Quality Improvement Methodology; Using Statistical Process Control Methodology; Human Factors in Quality Improvement, Random Safety Audits, Root Cause Analysis, and Failure Mode and Eff...
