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Cancer imposes daunting effects on the nervous system Brain cancer is one of the most devastating diagnoses a physician can deliver. Cancer of the nervous system can take many different forms. Treatment is specific to the type of malignancy, its location in the nervous system and, increasingly, its molecular characteristics. The challenges manifest further when management choices need to be made, and multidisciplinary approaches are required. Additional complexities arise in children, where the developing neurological system requires more sensitive treatment. Neuro-oncology unmasks the complexities to provide a straightforward guide to cancers of the nervous system. Following a general appro...
The essential guide to managing tumors of the central nervous system Neuro-Oncology: The Essentials, Third Edition, is a comprehensive introduction to the fundamental science and core clinical concepts behind the successful multidisciplinary management of patients with brain and spine tumors. Among the updates to this new edition are eight new chapter topics, including: Endoscopic Approaches, Pediatric Supratentorial Tumors, and Neuro-Oncology in the Developing World. The book begins with basic science, progresses to clinical applications, and includes a robust section on specific tumor types. Key Features: A major revision, with a 20% increase in content and over 35% increase in figures Edi...
A general introduction to the principles of diagnosis and treatment of children with brain tumors is presented. Molecular characterization of solid tumors is also presented. Molecular pathways provide putative targets for new therapies. High resolution magic spinning NMR spectroscopy is explained, which is used to determine metabolic profiles for small pieces of intact tissue and whole cells in culture. The differences between adult and pediatric brain tumors are outlined. It is emphasized that pediatric low-grade gliomas need lower doses of antidrugs such as cisplatin/etoposide. It is explained that tumor suppressor genes and oncogenes play a crucial role in the development and progression ...
It is estimated that the functionally significant body of knowledge for a given medical specialty changes radically every 8 years. New specialties and "sub-specialization" are occurring at approximately an equal rate. Historically, established journals have not been able either to absorb this increase in publishable material or to extend their readership to the new specialists. International and national meetings, symposia and seminars, workshops, and newsletters suc cessfully bring to the attention of physicians within developing spe cialties what is occurring, but generally only in demonstration form without providing historical perspective, pathoanatomical corre lates, or extensive discus...
First multi-year cumulation covers six years: 1965-70.
From joys and sorrows, life and death, and everything in between, this book offers a heartfelt and thought-provoking collection of personal reflections of a pediatric oncologist, along with stunning photographic visuals that capture the many moods of nature. Raw, honest, and unfiltered, this book explores the inevitability of death and the struggles of patients and their families and physicians and provides a unique perspective on empathy, hope, loss, triumph, faith, humanity, and devotion. From the first page, the readers will embark on a glorious, breathtaking, and emotional journey through a variety of human emotions painted using words, powerful photographs, and symbolism. From the excit...
At 46 with a wife and two children and a successful business, the unthinkable happened – Brain Cancer. As a multiple sport athlete and an avid golfer, having the core of his being stripped away and knowing it would never come back was devastating. This book is a “no holds barred” full-fledged cancer experience for the reader. It is a journey through the unknown which includes everything from fear, sadness, panic, loneliness and anger to flat out gut-wrenching laughter. The intent is to give a cancer patient, a patient-to-be and their loved ones the strength to fight the battle they must fight and the courage to adjust to whatever kind of future lies ahead.
Topics include: Neoplastic Meningitis and Epidural Metastases: Evaluation and Management; Management of Brain Metastases: Surgery, Radiation, or Both?; Meningiomas/Nerve Sheath Tumors/Pituitary Tumors: Diagnosis and Treatment; Medulloblastoma/Primitive Neuroectodermal Tumor and Germ Cell Tumors: The Uncommon but Potentially Curable Primary Brain Tumors; Primary CNS Lymphoma: Overview of Current Treatment Strategies; Anaplastic Gliomas: Radiation, Chemotherapy, or Both?; Low Grade Gliomas: When and How to Treat?; Glioblastoma Multiforme: Overview of Current Treatment and Future Perspectives.