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Resistance to Anti-Cancer Therapeutics Targeting Receptor Tyrosine Kinases and Downstream Pathways
This volume comprehensively covers the multiplicity and diversity of mechanisms underlying patient resistance to currently approved anti-cancer drugs, including tyrosine kinase inhibitors and monoclonal antibodies, blockers of growth factor receptors and their downstream pathways, which play essential functions in cancer progression. Each chapter will cover a specific group of targets and the cognate drugs, along with molecular modes of innate and evolving resistance.
Transmission Electron Microscopy
This profusely illustrated text on Transmission Electron Microscopy provides the necessary instructions for successful hands-on application of this versatile materials characterization technique. The new edition also includes an extensive collection of questions for the student, providing approximately 800 self-assessment questions and over 400 questions suitable for homework assignment.
Medical Image Computing and Computer-Assisted Intervention -- MICCAI 2010
The three-volume set LNCS 6361, 6362 and 6363 constitutes the refereed proceedings of the 13th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2010, held in Beijing, China, in September 2010. Based on rigorous peer reviews, the program committee carefully selected 251 revised papers from 786 submissions for presentation in three volumes. The first volume includes 84 papers organized in topical sections on computer-aided diagnosis, planning and guidance of interventions, image segmentation, image reconstruction and restoration, functional and diffusion-weighted MRI, modeling and simulation, instrument and patient localization and tracking, quantitative image analysis, image registration, computational and interventional cardiology, and diffusion tensor MR imaging and analysis.
Transmission Electron Microscopy
This groundbreaking text provides the necessary instructions for hands-on application of this versatile materials characterization technique and is supported by over 600 illustrations and diagrams.
Water-Insoluble Drug Formulation
Properties and Formulation: From Theory to Real-World Application Scientists have attributed more than 40 percent of the failures in new drug development to poor biopharmaceutical properties, particularly water insolubility. Issues surrounding water insolubility can postpone or completely derail important new drug development. Even the much-needed reformulation of currently marketed products can be significantly affected by these challenges. More recently it was reported that the percentage increased to 90% for the candidates of new chemical entities in the discovery stage and 75% for compounds under development. In the most comprehensive resource on the topic, this third edition of Water-In...
Informed Traders as Liquidity Providers
Alexandra Hachmeister’s thesis empirically analyzes and positively answers the question whether informed traders provide liquidity in an open limit order book. The analyses include a detailed market description of the German equity market, a new methodological approach for the identification of informed traders as well as the analysis of the individual liquidity providing and demanding behavior of the identified informed traders.
Russia in Transition
Russia in Transition: Regional Integration, Media Censorship and Culture Institutes is an attempt to discuss the context of transition in the period of the last two decades in Russia, and give the panorama of Putin’s ruling ideology in national and social development by examining his regional policy and media policy both diplomatically and domestically. Russia-China relations will be the crucial defining factor in terms of international security in the Asian-Pacific region and, as such, are discussed in detail in this volume. The book is a result of a research program sponsored by the National Science Council, Ministry of Foreign Affairs, Yuan Ze University, Taiwan, ROC, and the Asian Stud...
Energy Minimization Methods in Computer Vision and Pattern Recognition
This book constitutes the refereed proceedings of the 6th International Conference on Energy Minimization Methods in Computer Vision and Pattern Recognition held in Ezhou, China, in August 2007. Twenty-two full papers are presented along with fifteen poster papers. The papers are organized into topical sections on algorithms, applications, image parsing, image processing, motion, shape, and three-dimensional processing.
