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Water-Insoluble Drug Formulation
Scientists have attributed more than 40 percent of the failures in new drug development to poor biopharmaceutical properties, particularly water insolubility. Issues surrounding water insolubility can postpone, or completely derail, important new drug development. Even much-needed reformulation of currently marketed products can be significantly affected by these challenges. Water Insolubility is the Primary Culprit in over 40% of New Drug Development Failures The most comprehensive resource on the topic, this second edition of Water Insoluble Drug Formulation brings together a distinguished team of experts to provide the scientific background and step-by-step guidance needed to deal with so...
Medical Image Computing and Computer-Assisted Intervention -- MICCAI 2010
The three-volume set LNCS 6361, 6362 and 6363 constitutes the refereed proceedings of the 13th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2010, held in Beijing, China, in September 2010. Based on rigorous peer reviews, the program committee carefully selected 251 revised papers from 786 submissions for presentation in three volumes. The third volume includes 83 papers organized in topical sections on segmentation and modeling, robotics, motion modeling and computer-assisted interventions, image reconstruction, enhancement and representation, and computer-aided diagnosis.
Water-Insoluble Drug Formulation
Properties and Formulation: From Theory to Real-World Application Scientists have attributed more than 40 percent of the failures in new drug development to poor biopharmaceutical properties, particularly water insolubility. Issues surrounding water insolubility can postpone or completely derail important new drug development. Even the much-needed reformulation of currently marketed products can be significantly affected by these challenges. More recently it was reported that the percentage increased to 90% for the candidates of new chemical entities in the discovery stage and 75% for compounds under development. In the most comprehensive resource on the topic, this third edition of Water-In...
Resistance to Anti-Cancer Therapeutics Targeting Receptor Tyrosine Kinases and Downstream Pathways
This volume comprehensively covers the multiplicity and diversity of mechanisms underlying patient resistance to currently approved anti-cancer drugs, including tyrosine kinase inhibitors and monoclonal antibodies, blockers of growth factor receptors and their downstream pathways, which play essential functions in cancer progression. Each chapter will cover a specific group of targets and the cognate drugs, along with molecular modes of innate and evolving resistance.
Transmission Electron Microscopy
This profusely illustrated text on Transmission Electron Microscopy provides the necessary instructions for successful hands-on application of this versatile materials characterization technique. The new edition also includes an extensive collection of questions for the student, providing approximately 800 self-assessment questions and over 400 questions suitable for homework assignment.
Nuclear Power Plants: Innovative Technologies for Instrumentation and Control Systems
This book is a compilation of selected papers from the fifth International Symposium on Software Reliability, Industrial Safety, Cyber Security and Physical Protection of Nuclear Power Plant, held in November 2020 in Beijing, China. The purpose of this symposium is to discuss Inspection, test, certification and research for the software and hardware of Instrument and Control (I&C) systems in nuclear power plants (NPP), such as sensors, actuators and control system. It aims to provide a platform of technical exchange and experience sharing for those broad masses of experts and scholars and nuclear power practitioners, and for the combination of production, teaching and research in universities and enterprises to promote the safe development of nuclear power plant. Readers will find a wealth of valuable insights into achieving safer and more efficient instrumentation and control systems.
Russia in Transition
Russia in Transition: Regional Integration, Media Censorship and Culture Institutes is an attempt to discuss the context of transition in the period of the last two decades in Russia, and give the panorama of Putin’s ruling ideology in national and social development by examining his regional policy and media policy both diplomatically and domestically. Russia-China relations will be the crucial defining factor in terms of international security in the Asian-Pacific region and, as such, are discussed in detail in this volume. The book is a result of a research program sponsored by the National Science Council, Ministry of Foreign Affairs, Yuan Ze University, Taiwan, ROC, and the Asian Stud...
Transmission Electron Microscopy
This groundbreaking text provides the necessary instructions for hands-on application of this versatile materials characterization technique and is supported by over 600 illustrations and diagrams.
It's All Analytics!
It's All Analytics! The Foundations of AI, Big Data and Data Science Landscape for Professionals in Healthcare, Business, and Government (978-0-367-35968-3, 325690) Professionals are challenged each day by a changing landscape of technology and terminology. In recent history, especially in the last 25 years, there has been an explosion of terms and methods that automate and improve decision-making and operations. One term, "analytics," is an overarching description of a compilation of methodologies. But AI (artificial intelligence), statistics, decision science, and optimization, which have been around for decades, have resurged. Also, things like business intelligence, online analytical pro...
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