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An introductory text that emphasizes the underlying algorithmic ideas that are driving advances in bioinformatics. This introductory text offers a clear exposition of the algorithmic principles driving advances in bioinformatics. Accessible to students in both biology and computer science, it strikes a unique balance between rigorous mathematics and practical techniques, emphasizing the ideas underlying algorithms rather than offering a collection of apparently unrelated problems. The book introduces biological and algorithmic ideas together, linking issues in computer science to biology and thus capturing the interest of students in both subjects. It demonstrates that relatively few design ...
This book constitutes the thoroughly refereed post-proceedings of the RECOMB 2004 Satellite Workshop on Regulatory Genomics, RRG 2004, held in San Diego, CA, USA in March 2004. The 10 revised full papers presented were carefully reviewed and improved for inclusion in the book. The papers address a broad variety of aspects of regulatory genomics including classification, functional module detection, proteonomics, sampling, kernel methods, TF binding motifs, gene expression data analysis, regulatory network model learning, RNA regulatory sequence motifs, DNA regulatory sequence motifs, parameter landscape analysis, and biological network regulation.
Research in the field of gene regulation is evolving rapidly in the ever-changing scientific environment. Advances in microarray techniques and comparative genomics have enabled more comprehensive studies of regulatory genomics. The study of genomic binding locations of transcription factors has enabled a more comprehensive modeling of regulatory networks. In addition, complete genomic sequences and comparison of numerous related species have demonstrated the conservation of non-coding DNA sequences, which often provide evidence for cis-regulatory binding sites. Systematic methods to decipher the regulatory mechanism are also crucial for corroborating these regulatory networks; key to these ...
This volume contains the papers presented at the 10th Annual International Conference on Research in Computational Molecular Biology (RECOMB 2006), which was held in Venice, Italy, on April 2–5, 2006
This volume presents the proceedings of the third workshop on Information Systems and Artificial Intelligence, organized by the German Computer Science Society. The 11 invited contributions by well known researchers and developers working in the fields of databases and knowledge representation systems are centered around the topic of management and processing of complex data structures; they give a representative snapshot of the state-of-the-art in this fruitful interdisciplinary research area important for further progress in both, information systems and artificial intelligence. Most of the papers stress the demands for new or extended formalisms and their deductive capabilities, including an analysis of their formal properties for managing complex structures.
This book constitutes the refereed proceedings of the 4th International Workshop on Algorithms in Bioinformatics, WABI 2004, held in Bergen, Norway, in September 2004. The 39 revised full papers presented were carefully reviewed and selected from 117 submissions. Among the topics addressed are all current issues of algorithms in bioinformatics, such as exact and approximate algorithms for genomics, genetics, sequence analysis, gene and signal recognition, alignment, molecular evolution, phylogenetics, structure determination or prediction, gene expression and gene networks, proteomics, functional genomics, and drug design.
This volume presents a compelling collection of state-of-the-art work in algorithmic computational biology, honoring the legacy of Professor Bernard M.E. Moret in this field. Reflecting the wide-ranging influences of Prof. Moret’s research, the coverage encompasses such areas as phylogenetic tree and network estimation, genome rearrangements, cancer phylogeny, species trees, divide-and-conquer strategies, and integer linear programming. Each self-contained chapter provides an introduction to a cutting-edge problem of particular computational and mathematical interest. Topics and features: addresses the challenges in developing accurate and efficient software for the NP-hard maximum likelih...
This book constitutes the refereed proceedings of the 16th International Workshop on Algorithms in Bioinformatics, WABI 2016, held in Aarhus, Denmark. The 25 full papers together with 2 invited talks presented were carefully reviewed and selected from 54 submissions. The selected papers cover a wide range of topics from networks, tophylogenetic studies, sequence and genome analysis, comparative genomics, and mass spectrometry data analysis.
This book constitutes the refereed proceedings of the 11th Annual Symposium on Combinatorial Pattern Matching, CPM 2000, held in Montreal, Canada, in June 2000.The 29 revised full papers presented together with 3 invited contributions and 2 tutorial lectures were carefully reviewed and selected from 44 submissions. The papers are devoted to current theoretical and algorithmic issues of searching and matching strings and more complicated patterns such as trees, regular expression graphs, point sets and arrays as well as to advanced applications of CPM in areas such as Internet, computational biology, multimedia systems, information retrieval, data compression, and pattern recognition.
This book presents the proceedings of the International Computer Symposium 2014 (ICS 2014), held at Tunghai University, Taichung, Taiwan in December. ICS is a biennial symposium founded in 1973 and offers a platform for researchers, educators and professionals to exchange their discoveries and practices, to share research experiences and to discuss potential new trends in the ICT industry. Topics covered in the ICS 2014 workshops include: algorithms and computation theory; artificial intelligence and fuzzy systems; computer architecture, embedded systems, SoC and VLSI/EDA; cryptography and information security; databases, data mining, big data and information retrieval; mobile computing, wireless communications and vehicular technologies; software engineering and programming languages; healthcare and bioinformatics, among others. There was also a workshop on information technology innovation, industrial application and the Internet of Things. ICS is one of Taiwan's most prestigious international IT symposiums, and this book will be of interest to all those involved in the world of information technology.