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Decoding Darkness
Working from the intriguing hypothesis that Alzheimer's dementia is the result of a renegade protein-beta amyloid-Tanzi and others set out to find the gene responsible for its production. Decoding Darkness takes us deep into the minds and far-flung labs of many a prominent researcher, offering an intimate view of the high stakes of molecular genetics, the revolution that propels it, the obstacles that threaten to derail it, and the families whose lives are so dependent upon it. Tanzi and Parson ultimately reveal that Alzheimer's, like heart disease, may be effectively treated-even prevented.
The Healing Self
Heal yourself from the inside out Our immune systems can no longer be taken for granted. Current trends in public healthcare are disturbing: our increased air travel allows newly mutated bacteria and viruses to spread across the globe, antibiotic-resistant strains of bacteria outstrip the new drugs that are meant to fight them, deaths due to hospital-acquired infections are increasing, and the childhood vaccinations of our aging population are losing their effectiveness. Now more than ever, our well-being is at a dangerous crossroad. But there is hope, and the solution lies within ourselves. The Healing Self is the new breakthrough book in self-care by bestselling author and leader in integr...
Super Genes
"You are not simply the sum output of your genome," write Deepak Chopra and Rudy Tanzi, Director of the Genetics and Aging Research Unit at Massachusetts General Hospital. "You are the user and inventor of your genome." For years it was accepted knowledge that genes were fixed components of our bodies, and that we as individuals were incapable of altering our genetic make-up. Yet groundbreaking research suggests that changes in lifestyle and diet can greatly influence our genetic predispositions to disease and certain physical and psychological behaviours. Moreover, the adoption of ancient Vedic practices such as yoga and meditation can create genetic mutations that allow us to lead longer and healthier lives. Super Genes includes meditation and breathing practical exercises, as well as information on how to manage risk factors for disease. Combining scientific research with insights from ancient traditions, Chopra and Tanzi show how we need not be at the mercy of our genetic inheritance. Instead, they argue, we have the power to rewire our super genes for health and happiness.
Neurodegeneration
Most textbooks on neurodegenerative disorders have used a classification scheme based upon either clinical syndromes or anatomical distribution of the pathology. In contrast, this book looks to the future and uses a classification based upon molecular mechanisms, rather than clinical or anatomical boundaries. Major advances in molecular genetics and the application of biochemical and immunocytochemical techniques to neurodegenerative disorders have generated this new approach. Throughout most of the current volume, diseases are clustered according to the proteins that accumulate within cells (e.g. tau, α-synuclein and TDP-43) and in the extracellular compartments (e.g. β-amyloid and prion ...
Molecular Mechanisms of Dementia
The past decade has witnessed a revolution in the attempts of scientists to under stand the molecular basis of dementia. Although dementia, as defined by global cogni tive decline involving gradual loss of memory, reasoning, judgment, and orientation, presents most commonly in the form of Alzheimer's disease (AD), an assortment of other less common disorders, such as prion and Pick's disease, can also lead to symp toms that are similar to those observed in patients with AD. The primary goal of Molecular Mechanisms of Dementia is to address the various mechanisms and multi faceted approaches currently being employed to more clearly delineate the etiological and pathogenic events responsible f...
Before I Forget
"Working with Vanity Fair contributing editor Michael Shnayerson, B. and her husband Dan share B.'s unfolding story on dealing with early-onset Alzheimer's. Crafted in short chapters that interweave their narrative with ... advice, readers learn in small bites about dealing with Alzheimer's disease's day-to-day challenges, the family tensions, and ways of coping, as well as gain tips on diet and exercise from a lifestyle maven using her decades of expertise in a new and unexpected way"--
Super Brain
Two pioneers in health - Dr Deepak Chopra and Prof Rudolph E. Tanzi, one of the world's foremost experts on the causes of Alzheimer's - share a bold new understanding of the brain and a prescriptive plan for how we can use it to achieve physical, mental and spiritual well-being. In his bestselling books Ageless Body, Timeless Mind and Reinventing the Body, Resurrecting the Soul, Deepak Chopra reveals 'the forgotten miracle' - the body's infinite capacity for change and renewal. Now, Chopra focuses his attention on a part of the body undergoing intense study and radical reevaluation: the brain. No one is better able to share the latest breakthroughs in neuroscience than preeminent neurologist Rudolph E. Tanzi and, together, Chopra and Tanzi present a new vision of the brain together with a practical plan for how to use it to achieve higher levels of success and fulfilment. They contend that by using techniques and skills such as mindfulness, intention and meditation, we can create new neural pathways in the brain. Thus, we can transform it into our most powerful tool for achieving health, happiness and enlightenment.
Alzheimer's Disease Drug Development
Provides a definitive overview of the complex ecosystem facilitating Alzheimer's Disease drug research and development. Demonstrates a drug's journey from in the lab, clinical trial testing, regulatory review, and marketing by pharmaceutical companies. Details the use of artificial intelligence, clinical trial management, and financing models.
Alzheimer's Disease
Alzheimer's Disease is an ever present problem affecting millions of people around the world and, as people's average lifespan lengthens, its prevalence is set to increase. A global effort is needed to combat the disease, including research to investigate the causes, development of effective treatments and, ultimately, prevention of the disease. Published every two years, these timely books discuss the very latest research. This new volume provides a unique source of reference to the important work being done in this field, it gives academics and clinicians an opportunity to learn about cutting edge developments and covers all aspects of Alzheimer's Disease, including diagnosis, clinical course, epidemiological course and therapeutics and disease mechanisms. Alzheimer's Disease: Advances in Etiology, Pathogenesis and Therapeutics will provide essential information for basic and clinical researchers in Alzheimer's Disease and other dementias as well as for those who care for patients.
Alzheimer's Disease
This book examines every major aspect of Alzheimer disease at a time when there has been no scholarly research volume on the subject published in the last 3-5 years. This edition includes expanded coverage of the cellular-level exploration of related dementing disorders, with in-depth presentation of prion diseases, Pick's disease, fronto-temporal disorders, transgenic models, and biochemistry of presenilins.
