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Cell Culture in the Neurosciences
A fundamental problem in neuroscience is the elucidation of the cellular and molecular mechanisms underlying the development and function of the nervous system. The complexity of organization, the heteroge neity of cell types and their interactions, and the difficulty of controlling experimental variables in intact organisms make this a formidable task. Because of the ability that it affords to analyze smaller components of the nervous system (even single cells in some cases) and to better control experimental variables, cell culture has become an increasingly valuable tool for neuroscientists. Many aspects of neural development, such as proliferation, differentiation, synaptogenesis, and my...
Mitochondrial Disorders Caused by Nuclear Genes
Mitochondrial cytopathies are mutations in the inherited maternal mitochondrial genome, or the nuclear DNA-mutation. Mitochondrial respiratory chain disorders (RCD) are a group of genetically and clinically heterogeneous diseases, due to the fact that protein components of the respiratory chain are encoded by both mitochondrial and nuclear genomes and are essential in all cells. In addition, the biogenesis, structure and function of mitochondria, including DNA replication, transcription, and translation, all require nuclear encoded genes. Since mitochondria are present in every cell, every tissue, mitochondrial disorder usually affects multiple organs.
Neurobehavioral Manifestations of Neurological Diseases: Diagnosis & Treatment, An Issue of Neurologic Clinics
This important subject of Diagnosis of and Treatment for Neurobehavioral manifestations of neurologic disease is directed by three leaders of this field - Dr. Alizeza Minagar, Dr. Glen Finney, and Dr. Kenneth Heilman. Topics include: Neurobehavioral testing for mental status; Behavioral neurology of vascular neurology; Alzheimer's disease; Frontotemporal dementia; Traumatic brain injury; Parkinsonian Syndromes (e.g., Parkinson's disease, Lewy body dementia, progressive supranuclear palsy, corticobasal disease, multisystem atrophy); Behavioral neurology of multiple sclerosis and autoimmune encephalopathies; Infectious Diseases (Neuro-AIDS, Neurosyphilis, HSV); Neurobehavioral aspects of systemic disease; Neurobehavioral aspects of epilepsy; Behavioral neurology aspects of nutritional deficiencies; Neurobehavioral aspects of mitochondrial disease; and Medicinal-induced behavioral disorders.
Pediatric Radiology
Pediatric Radiology is a guided approach to effectively diagnosing 120 pathologies commonly encountered by pediatric radiologists and residents.
Handbook of Pediatric Epilepsy Case Studies, Second Edition
Research in the field of epilepsy will continue at a rapid pace, with the ultimate hope of curing many intractable epilepsy syndromes. Fully updated, this new edition is organized chronologically, from neonate through adolescence, and the handbook is the culmination of a group effort involving leading physicians and researchers whose contributions constitute a concise and practical reference for health professionals in training. Here the contributors review the recent flood of new information on the pathophysiology, genetics, and treatment of the various epilepsy syndromes, and the volume is distilled into an easy-to-use guide. Fully updated text reviewing the latest research on the pathophysiology, genetics, and treatment of the various epilepsy syndromes. Thorough descriptions of the different syndromes commonly encountered in clinical practice across the pediatric range. Extensive resource section provided. Contributors describe why they chose each particular case, what they learned, and how it changed their practice. The book includes the most recent classification and nomenclature published by the International League Against Epilepsy.
Physician's Field Guide to Neuropsychology
This unique volume teaches those in the medical fields about the scientific value of neuropsychology in assessing cognition, the 6th vital sign, as part of well integrated collaborative care. It offers physicians a comprehensive tour of the many dimensions neuropsychology can add to primary and specialized medical care across the lifespan. Noted experts examine cognitive ramifications of a wide range of medical, psychological, and neuropsychological conditions, among them brain tumors, stroke, epilepsy, pediatric and adult TBI, schizophrenia, and adult ADHD. The book’s generous selection of case examples demonstrates the benefits of cognitive assessment in building accurate diagnoses, bett...
Advances in Genetics
Advances in Genetics, Volume 98 provides the latest information on the rapidly evolving field of genetics, presenting new medical breakthroughs that are occurring as a result of advances in our knowledge of the topic. The book continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines, critically analyzing future directions. Topics of interest in this updated volume include the Genetics of Mitochondrial Disease, a Genetic analysis of depression, happiness and other normal personality traits, The Evolving Centromere and Kinetochore, and The Genetics of Parkinson's Disease. - Critically analyzes future directions for the study of clinical genetics - Written and edited by recognized leaders in the field - Presents new medical breakthroughs that are occurring as a result of advances in our knowledge of genetics
Pediatric Nutrition Handbook
The last decade has seen an explosion of medical information in regards to the nutrition care and management of children. While nutritional therapies have expanded, the treatment choices have become increasingly complex. This exciting title addresses the extensive amount of information available to practitioners in a concise, accessible fashion via a series of algorithms. It focuses on the normal growing healthy child from birth through adolescence, covering common pediatric diseases and disorders through a series of flows charts which outline step-by-step nutritional processes for pediatric patients. The highly visual format of the book allows the practitioner to make rapid, evidence based choices. Features: Unique algorithm approach to the largest dietetic specialism Highly visual approach allows quick decision making All algorithms and text built on evidence-based research Covers the pediatric phase from birth to adolescence Includes common childhood diseases and disorders
