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Essentials of Genomic and Personalized Medicine
Derived from the comprehensive two-volume set, Genomic and Personalized Medicine also edited by Drs. Willard and Ginsburg, this work serves the needs of the evolving population of scientists, researchers, practitioners and students that are embracing one of the most promising avenues for advances in diagnosis, prevention and treatment of human disease. From principles, methodology and translational approaches to genome discoveries and clinical applications, Essentials of Genomic and Personalized Medicine will be a valuable resource for various professionals and students across medical disciplines, including human genetics and genomics, oncology, neuroscience, gene therapy, molecular medicine...
Evidence-Based Cardiology
Evidence based Cardiology was first published in 1998 to universal acclaim. Now, with the move towards more patient focused health care and at the same time increased emphasis on health economics, evidence-based practice is a more important force in health care delivery than ever. This new third edition, written by the world’s leading cardiologists, provides graded evidence-based reviews of the major trials together with recommendations for optimum management, and now includes new grading and recommendation methodology. This is a unique book in the field of cardiology, and the largest evidence based clinical cardiology text.
Comprehensive Toxicology
An explosive increase in the knowledge of the effects of chemical and physical agents on biological systems has led to an increased understanding of normal cellular functions and the consequences of their perturbations. The 14-volume Second Edition of Comprehensive Toxicology has been revised and updated to reflect new advances in toxicology research, including content by some of the leading researchers in the field. It remains the premier resource for toxicologists in academia, medicine, and corporations. Comprehensive Toxicology Second Edition provides a unique organ-systems structure that allows the user to explore the toxic effects of various substances on each human system, aiding in providing diagnoses and proving essential in situations where the toxic substance is unknown but its effects on a system are obvious. Comprehensive Toxicology Second Edition is the most complete and valuable toxicology work available to researchers today. Contents updated and revised to reflect developments in toxicology research Organized with a unique organ-system approach Features full color throughout Available electronically on sciencedirect.com, as well as in a limited-edition print version
Genomics and Clinical Medicine
An important milestone in medicine has been the recent completion of the Human Genome Project. The identification of 30,000 genes and their regulatory proteins provides the framework for understanding the metabolic basis of disease. This advance has also laid the foundation for a broad range of genomic tools that have opened the way for targeted genetic testing in a number of medical disorders. This book is designed to be the first major text to discuss genomics-based advances in disease susceptibility, diagnosis, prognostication,and prediction of treatment outcomes in various areas of medicine. After building a strong underpinning in the basic concepts of genomics, the authors of this book, all leaders in the field, proceed to discuss a wide range of clinical areas and the applications now afforded by genomic analysis.
Advances in Machinery, Materials Science and Engineering Application
Keeping up to date with advances in material science and applied engineering is essential for those working in the field if they are to understand and tackle the challenges they face in an efficient manner and adopt the best and most appropriate solutions available. This book presents the proceedings of MMSE 2022, the 8th International Conference on Advances in Machinery, Materials Science and Engineering Application, held as a hybrid event (both in-person and online) in Wuhan, China, on 23 and 24 July 2022. For the past 12 years, the MMSE international conferences have collated recent advances and experiences, identified emerging trends in technology and encouraged lively debate between stu...
The Molecular Basis for the Link Between Maternal Health and the Origin of Fetal Congenital Abnormalities
This e-book discusses the molecular relationship between biological systems and risk factors for in-utero oxidative insults, maternal health and the impact on fetus at different critical developmental time windows (prenatal or even postnatal). Plausibly, prenatal and early postnatal periods are the most critical "windows" to oxidative stress programming insults. Pro-oxidative stress is a common feature of many conditions associated with adverse fetal growth and/or preterm birth, such as pre-eclampsia, diabetes, smoking, malnutrition or excessive nutrition, infection or inflammation. Oxidative.
Coronary Care Manual
A comprehensive coronary care textbook for medical, nursing and paramedic staff The Coronary Care Manual, 2nd Edition is a practical medical manual designed to assist with management of the acute coronary patient. This respected medical resource is written by a group of coronary experts, both Australian and international. Its aim is to strike a balance between a large and rapidly-changing evidence base and practical application in the Coronary Care Unit, Intensive Care Unit, Emergency Department and the ambulance. The second edition of this important health textbook covers an extensive range of coronary care medicine, providing a handy companion for a night 'on call'. Chapter topics in the Coronary Care Manual, 2nd Edition include pathophysiology, drug and non-drug therapies and postcoronary management, with chapters organised into subsections. Completely redesigned with fresh, new artwork, this new edition of the Coronary Care Manual is organised to suit academics and medical practitioners alike.
Current Topics in Human Genetics
The sequencing of the human genome has brought human genetics into a new era of study resulting in the generation of an explosive amount of information. Application of genomic, proteomic, and bioinformatics technologies to the study of human genetics has made it possible for human genetic diseases to be studied on an unprecedented scale, both in silico and in the wet lab. This volume provides up-to-date coverage of the broad range of research topics in this fascinating area. In the first part of the book, a whole spectrum of approaches to human genetics research is reviewed for both background and the latest progress. In the second, important topics related to genetic research of various complex human diseases are discussed. The robust content and diverse array of subjects allow the book to serve as both a concise ?encyclopedia? that introduces basic and essential concepts of human genetics and an in-depth review of the current understanding of genetic research in human diseases.
