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This volume provides a comprehensive treatment of the latest research on oxidative stress and antioxidant defenses in all types of aerobic organisms. This book investigates oxidative stress in prokaryotes, protists, plants, fungi, vertebrates, and invertebrates, stimulating cross-fertilization among diverse fields. In addition, it explains the basic science of oxygen activation and oxidative stress as a foundation for more advanced material, making this book useful as a resource for both specialists and non-specialists.
Ventilator Management for the Cardiac Patient; Management of Post-Operative Complications in the Cardiac Surgery Patient; Guidelines Relevant to Care in the Cardiac Intensive Care Unit--to keep the book and you up to date. yPresents the text in a new, full-color design and layout for a more visually-appealing and accessible format that makes finding the information you need quick and easy.
Platelets are tiny blood cells that help the body form clots to stop bleeding. Antiplatelet medications, such as aspirin and clopidogrel, are commonly used to thin the blood which limits clotting and reduces the risk of heart attack. This book is a comprehensive guide to blood platelets for haematologists. Beginning with discussion on platelet structure, morphology, function and physiology, the next chapters cover the role of calcium in platelet activation and calcium modulation by cyclic nucleotides. The following sections explain the pharmacology of antiplatelet drugs, antiplatelet therapies, aspirin resistance, and the association of diabetes mellitus with major platelet dysfunction. The ...
Game Theoretical Applications to Economics and Operations Research deals with various aspects of game theory and their applications to Economics and OR related problems. It brings together the contributions of a wide spectrum of disciplines such as Statistics, Mathematics, Mathematical Economics and OR. The contributions include decision theory, stochastic games, cooperative and noncooperative games. The papers in the volume are classified under five different sections. The first four sections are devoted to the theory of two-person games, linear complimentarity problems and game theory, cooperative and noncooperative games. The fifth section contains diverse applications of these various theories. Taken together they exhibit a rich versatility of these theories and lively interaction between the mathematical theory of games and significant economic problems.
Dr. Ballantyne—one of the foremost lipid experts in the world and recruited by Dr. Braunwald’s Heart Disease editorial team—together with a stellar cast of contributors provides all of the scientific and clinical information you need to effectively manage every aspect of dyslipidemia. From basic science to pathogenesis of atherothrombotic disease to risk assessment and the latest therapy options, this new title in the Braunwald’s Heart Disease family offers unparalleled coverage and expert guidance on lipidology in a straightforward, accessible, and user-friendly style. • Features the expertise of one of the foremost experts in the field, ensuring you get authoritative guidance with the most definitive knowledge available. • Contains extensive clinically relevant information covering risk assessment, therapy, special patient populations, and experimental therapies, including targeting HDL to help you effectively manage any challenges you face. • Uses treatment algorithms for easy access to key content. • Presents current practice guidelines that assist in the decision-making process.
Cardiovascular immunology is a newly emerging research area, investigating the crosstalk between the cardiovascular and the immune system. This crosstalk is evident through (1) crucial immunological capacities and functions of cardiovascular cell types, including cardiomyocytes, fibroblasts, endothelial cells, pericytes and cardiac resident macrophages, (2) the impact of aberrant immune function on the development of cardiovascular disease such as atherosclerosis, direct and indirect immune-mediated heart disease and vasculitis, and (3) the crucial role of the immune system in cardiac repair and regeneration. The Immunology of Cardiovascular Homeostasis and Pathology covers all these aspects of cardiovascular immunology, starting with homeostatic immunological functions of traditional cardiovascular cell types, and moving then to the role of the immune system in cardiovascular pathology and to recent research into targeting the immune system to boost cardiac healing and regeneration.
This timely volume describes the contributions of free radicals and reactive oxygen species to disease processes in a variety of tissues. Topics include the roles of lipid peroxide-modified lipoproteins in atherosclerosis, peroxidation products in retinopathy, reactive oxygen species and neutrophils in mycardial ischemia-reflow injury, iron and reactive oxygen species in hemoglobin-mediated CNS damage and in asbestos-mediated lung injury. Critical reviews examine the evidence for radical species in ethanol-induced liver injury and in muscular dystrophy. The wealth of new information presented makes this book valuable for teaching and an important reference volume for researchers exploring problems in human disease.
After more than three decades of research, the subject of complementarity problems and its numerous extensions has become a well-established and fruitful discipline within mathematical programming and applied mathematics. Sources of these problems are diverse and span numerous areas in engineering, economics, and the sciences. Includes refereed articles.