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The book aims to cover basic physiologic functions of melatonin, and its therapeutic applications in humans for a variety of clinically relevant disorders. This book contains chapters on the recent aspects of melatonin physiology, its receptors and their role in mitochondrial function, its immunomodulatory role and importance in seasonal dependent diseases, role in human reproduction, role in sleep, circadian rhythm and sleep disorders, role in neurologic disorders such as Parkinson’s disease, Alzheimer’s disease. Additionally, melatonin’s therapeutic use in neurobehavioral disorders in children, migraine and tension headache is also covered in this book. Melatonin’s antioxidant role...
There is growing interest in the field of melatonin research regarding its neurobiological mechanisms as well as its repercussions in clinical practice. Melatonin: Therapeutic Value and Neuroprotection explores melatonin’s neuroprotective effects and discusses the therapeutic potential of melatonin and melatonin agonists in treating neurodegenerative diseases and other ailments. Topics include: The basic aspects of melatonin’s physiology, including its production, bioavailability, and metabolism The functional importance of melatonin receptors and their role in mediating the therapeutic effectiveness of melatonin in cancer Melatonin’s effect on the regulation of blood pressure, sleep, ...
Essential Surgery is part of a nine volume series for Disease Control Priorities which focuses on health interventions intended to reduce morbidity and mortality. The Essential Surgery volume focuses on four key aspects including global financial responsibility, emergency procedures, essential services organization and cost analysis.
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For more than three decades, the Textbook of Neuropsychiatry and Clinical Neurosciences has been the gold standard for understanding the structural and functional foundations and rapidly evolving knowledge base of neuropsychiatric disorders. In the new edition, the esteemed editors have undertaken a complete reorganization, reconceptualizing the way the material is presented and integrating considerations of neuropsychiatric symptoms, syndromes, and treatments into chapters addressing the neuropsychiatry of neurodevelopmental disorders, acquired neurological conditions, neurodegenerative disorders, and primary psychiatric disorders. The result is a text that flows easily and logically from g...
Evidence continues to mount that foodborne illness imposes a staggering health burden in developing countries. However, standard approaches used by developed country governments to ensure food safety are not appropriate in settings where regulatory enforcement capacity is weak and most firms are small and informal. Thus, interventions to improve food safety in developing countries must take into account the constraints and incentives faced by producers in these countries. In this paper, we test the impact of two such interventions: subsidies for technologies that improve food safety and price premiums for safer produce. We examine the case of on-farm control of aflatoxin, a carcinogenic toxi...
In this thoroughly revised and restructured sixth edition, the editors offer a modern reconsideration of the core concepts, conditions, and approaches in neuropsychiatry, providing clinicians with the knowledge and tools they need to practice in this demanding field.