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Ecosystems-Centered Health and Care Innovation
The recent COVID-19 pandemic, along with the ongoing health issues related to persistent respiratory illnesses, has laid bare significant challenges, structural deficiencies, and critical vulnerabilities within the European Health and Care industries. These problems have resulted in notable tensions within healthcare establishments. Addressing these challenges requires enhanced coordination and stronger cooperation among various public and private stakeholders within the health and care ecosystems, not only within each country but also at the pan-European and global levels. This Research Topic seeks to highlight recent developments and scientific breakthroughs in the field of health ecosyste...
Confronting the Experts
Confronting the Experts brings together six personal case histories of challenges to establishment experts. The authors tell why they questioned conventional wisdom, what methods they used, how they dealt with the experts' response, and what lessons they learned. Because the book shows how powerful groups can get their way by gaining the support of intellectual authorities and also how these authorities can be challenged, it provides insights into the issues of power, dissent, and social change. Included are Sharon Beder's research on sewage and how it helped to undermine the credibility of the Sydney Water Board; Mark Diesendorf's scientific and social critique of fluoridation; Edward Herman's exposition of the flaws in the establishment perspective on terrorism; Harold Hillman's questioning of the validity of standard methods used in biology, such as subcellular fractionation and electron microscopy; Michael Mallory and Gordon Moran's challenge to the orthodox interpretation of a famous painting in Siena, Italy; and Dhirendra Sharma's confrontation with India's nuclear establishment.
Public-Private Partnerships as Drivers of Innovation in Healthcare, 2nd Edition
Multi-stakeholder collaborations involving partners from public and private sectors are essential to address global health challenges and to move precision medicine forward. This eBook assembles a collection of papers which either illustrate recent achievements or discuss new perspectives offered by public-private partnerships in healthcare. Publisher’s note: In this 2nd edition, the following article has been added: Laverty H and Meulien P (2019) The Innovative Medicines Initiative −10 Years of Public-Private Collaboration. Front. Med. 6:275. doi: 10.3389/fmed.2019.00275
Advances and Challenges in Nanomedicine
Nanotechnology is a multidisciplinary field that is revolutionizing the way we detect and treat damage to the human body. Nanomedicine applies nanotechnology to highly specific medical interventions for the prevention, diagnosis, and treatment of diseases. They are increasingly being used to overcome biological barriers in the body to improve the way we deliver compounds to specific tissues and organs. In particular, nanomedicines have been shown to be beneficial for stabilizing therapeutic compounds, overcoming obstacles to cellular and tissue uptake, and improving biodistribution of compounds to target sites in vivo. Nanomedicines have demonstrated significant therapeutic advantages for a ...
Therapeutic Implications of Circadian Rhythms
Circadian rhythms are biological processes displaying endogenous and entrainable oscillations of about 24 hours. They are driven by a group of genes called clock genes that have been widely observed in plants, animals and even in bacteria. In mammals, the core clock genes are rhythmically expressed in both the suprachiasmatic nucleus (SCN), the master clock residing in the hypothalamus, and almost all peripheral tissues where they control numerous target genes in a circadian manner, and thus affect many physiological and biochemical processes. Evidence suggests that disruption of the circadian rhythms (or desynchronization) is a significant risk factor for the development of metabolic diseas...
Current Chemotherapy
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