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Pharmaceuticals in the Environment
Following the success of the first edition, this pioneering study of pharmaceuticals in the environment has been updated and greatly extended. It includes the status of research on pharmaceuticals in soil, with attention to terrestrial and aquatic environments as well as new substance categories such as tetracylines and chinolones and the latest results concerning contamination of the environment and risk reduction.
Criminal Markets and Mafia Proceeds
This book estimates the proceeds of crime and mafia revenues for different criminal markets such as sexual exploitation, drugs, illicit cigarettes, loan sharking, extortion racketeering, counterfeiting, illicit firearms, illegal gambling and illicit waste management. It is the first time that scholars have adopted detailed methodologies to ensure the highest reliability and validity of the estimation. Overall, estimated proceeds of crime amount to € 22.8 billion: 1.5% of the Italian GDP. Of this, up to € 10.7 billion (0.7 of the GDP) may be attributable to the Italian mafias. These figures are considerably lower than the ones most frequently circulated on the news, without any details ab...
Basello
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The Ripple Effect
AS ALEX PRUD’HOMME and his great-aunt Julia Child were completing their collaboration on her memoir, My Life in France, they began to talk about the French obsession with bottled water, which had finally spread to America. From this spark of interest, Prud’homme began what would become an ambitious quest to understand the evolving story of freshwater. What he found was shocking: as the climate warms and world population grows, demand for water has surged, but supplies of freshwater are static or dropping, and new threats to water quality appear every day. The Ripple Effect is Prud’homme’s vivid and engaging inquiry into the fate of freshwater in the twenty-first century. The question...
Mass Spectrometry for Drug Discovery and Drug Development
Facilitates the discovery and development of new, effective therapeutics With coverage of the latest mass spectrometry technology, this book explains how mass spectrometry can be used to enhance almost all phases of drug discovery and drug development, including new and emerging applications. The book's fifteen chapters have been written by leading pharmaceutical and analytical scientists. Their contributions are based on a thorough review of the current literature as well as their own experience developing new mass spectrometry techniques to improve the ability to discover and develop new and effective therapeutics. Mass Spectrometry for Drug Discovery and Drug Development begins with an ov...
Mass Spectrometry in Structural Biology and Biophysics
The definitive guide to mass spectrometry techniques in biology and biophysics The use of mass spectrometry (MS) to study the architecture and dynamics of proteins is increasingly common within the biophysical community, and Mass Spectrometry in Structural Biology and Biophysics: Architecture, Dynamics, and Interaction of Biomolecules, Second Edition provides readers with detailed, systematic coverage of the current state of the art. Offering an unrivalled overview of modern MS-based armamentarium that can be used to solve the most challenging problems in biophysics, structural biology, and biopharmaceuticals, the book is a practical guide to understanding the role of MS techniques in biophy...
Mass Spectrometry
Provides a comprehensive description of mass spectrometry basics, applications, and perspectives Mass spectrometry is a modern analytical technique, allowing for fast and ultrasensitive detection and identification of chemical species. It can serve for analysis of narcotics, counterfeit medicines, components of explosives, but also in clinical chemistry, forensic research and anti-doping analysis, for identification of clinically relevant molecules as biomarkers of various diseases. This book describes everything readers need to know about mass spectrometry—from the instrumentation to the theory and applications. It looks at all aspects of mass spectrometry, including inorganic, organic, f...
PPARs in Cellular and Whole Body Energy Metabolism
This book is a printed edition of the Special Issue "PPARs in Cellular and Whole Body Energy Metabolism" that was published in IJMS
Cluster Secondary Ion Mass Spectrometry
Explores the impact of the latest breakthroughs in cluster SIMS technology Cluster secondary ion mass spectrometry (SIMS) is a high spatial resolution imaging mass spectrometry technique, which can be used to characterize the three-dimensional chemical structure in complex organic and molecular systems. It works by using a cluster ion source to sputter desorb material from a solid sample surface. Prior to the advent of the cluster source, SIMS was severely limited in its ability to characterize soft samples as a result of damage from the atomic source. Molecular samples were essentially destroyed during analysis, limiting the method's sensitivity and precluding compositional depth profiling....
