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The Guest Editors created a unique focus to the general topic of infectious diseases. They have focused on contemporary management of antibiotics used for procedures and infections. Articles are devoted to: Update on Antibiotic Prophylaxis for GU Procedures in Patients with Arificial Joint Replacement and Artifical Heart Valves; Asymptomatic Bacteriuria; Urinary Tract Infection and Bacteruria in Pregnancy; Resistance Patterns in Contemporary Antibiotics: ESBL and Beyond ; UTI and Neurogenic Bladder; Modern Guidelines for Skin and Bowel Prep for Open and Laparascopic GU Surgery; Work up of Pediatric Urinary Tract Infection; Pre Prostate Biopsy Rectal Culture and Post Biopsy Sepsis; Infection with Foreign Bodies: Mesh and Prostheses; Treatment of the Infected Stone; Sexually Transmitted Infections: Updated Guidelines and Treatment; Bacteruria/UTI in the Elderly; Treatement of Fungal Urinary Tract Infection; and STDs.
This issue provides much needed updates since Dr. Sheinfeld’s issue published in 2007. Dr. Lin has assembled expert authors to provide clinicians with the full breadth of clinical updates on testicular cancer. New to this issue are articles on clinical outcomes, survivorship, and several articles on the management of Nonseminomatous Germ Cell Tumors.
"In the novel Bel Canto, the Vice-President of a small Latin American country and about 50 others are being held hostage by terrorists. They have been held in the Vice-President's mansion for months and they fear they will not survive. Vice President Ruben Iglesias, who thought he would not live to feel once again the sensation of grass beneath his feet, stepped off the shale stone walkway and sank into the luxury of his own yard. He had stared at it every day from the living-room window but now that he was actually there it seemed like a new world. Had he ever walked around his own lawn in the evening? Had he made a mental note of the trees, the miraculous flowering bushes that grew up around the wall? What were they called? He dropped his face into the nest of deep purple blossoms and inhaled. Dear God, if he were to get out of this alive he would be attentive to his plants. (Patchett 2001: 281)"--
The past decade has been marked by the acceleration of our understanding of the molecular biology of cancer. Simultaneously, there have been increasing exigencies to diagnose, treat and follow cancer patients more economically. Biomarkers represent the marriage of science and economics. Biomarkers offer the potential to increase the precision of diagnosis, prognosis, and surveillance of urological malignancies. This issue presents the cutting-edge advances of biomarker technology to urologic oncology.
The Guest Editors have assembled top key opinion leaders to provide current reviews on the multidisciplinary approach to the management of high-grade bladder cancer. Articles are devoted to fluorescence cystoscopy, confocal laser endomicroscopy, narrow band imaging; Novel therapeutic approaches for recurrent nonmuscle invasive bladder cancer; Trimodality therapy in bladder cancer; the data and the reality of perioperative chemotherapy in muscle invasive bladder cancer; radical transurethral resection alone, robotic or partial cystectomy or extended lymphadenectomy: Neoadjuvant paradigm for drug development in muscle invasive bladder cancer; Novel biomarkers to predict response and prognosis in localized bladder cancer; Immunotherapy in Advanced/Metastatic Urothelial Cancer ; and Adjuvant Chemotherapy in High Grade Upper Tract Urothelial Cancer.
This issue of Clinics in Geriatric Medicine, guest edited by Drs. Thomas T. Yoshikawa and Dean C. Norman, is devoted to Infectious Diseases in Geriatric Medicine. Articles in this issue include: Host Resistance and Immunology of Aging; Clinical Features of Infection; Principles of Antimicrobial Therapy; Bacterial Pneumonia; Tuberculosis; Intraabdominal Infections; Infectious Diarrhea: Clostridium Difficile and Norovirus; Urinary Tract Infection; Herpes Zoster; Bone and Joint Infections; Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome; Infections in the Long-Term Care Setting; and Vaccinations.
The relationship between testosterone and prostate cancer physiology resulted in a Nobel Prize almost 5 decades ago; scientists have been studying testosterone and its relationship to heart health, diabetes, bone density, and muscle development throughout the subsequent 50 years. Included in this issue is the clinical experience and research expertise of many of the leaders in this field.
Benign prostatic hyperplasia and the resulting lower urinary tract symptoms is a major part of almost any urologist’s clinical practice. Due to the high prevalence of the disease in our aging population, new concepts and treatments are constantly entering the marketplace. Differences in patient preferences and desired outcomes require the practicing urologist to understand not only the pathophysiology of the disease but how specific treatments may be better suited for some patients and not others. This issue will address the current concepts and treatments available to urologists.
Urologists were early adaptors of robotic assisted laparoscopy, and pediatric urology similarly led in incorporating the technology into the surgical armamentarium for treating even the smallest infants. And it is in that tradition that this issue of Urologic Clinics of North America surveys the journey from the earliest pure laparoscopic procedures to the most advanced reconstruction possible today due to evolutions in technology. The issue begins with the procedure that arguably popularized the laparoscopic approach in pediatric urology—the laparoscopic orchiopexy, then posit the continued relevance of pure laparoscopy in the robotic era, before finally surveying contemporary advances in robotic-assisted pediatric urologic surgery. The issue is of relevance not only tor the novice contemplating a transition to laparoscopy or robotics but also for the seasoned minimally invasive surgeon seeking to enhance skills and augment his or her practice.