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Intracellular cell signaling is a well understood process. However, extracellular signals such as hormones, adipokines, cytokines and neurotransmitters are just as important but have been largely ignored in other works. Aimed at medical professionals and pharmaceutical specialists, this book integrates extracellular and intracellular signalling processes and offers a fresh perspective on new drug targets.
What is the appropriate way to taste wine at a restaurant? What type of wine is best served with catfish? 1000 Best Wine Secrets contains all the information novice wine drinkers and experienced connoisseurs alike need to feel comfortable in any restaurant, home or vineyard. 1000 Best Wine Secrets is the book for readers seeking the confidence to select and enjoy the perfect bottle from among the wines of the world. Includes such tips as: Secrets of buying great wine Detecting faulty wine and sending it back Serving wine like a pro Wine tips from around the globe—from Argentina to France and Spain to California Knowing when to drink wine
This masterful book from top experts provides clinical insights on reverse shoulder arthroplasty gleaned from hands-on refinement of shoulder replacement techniques. Years of significant biomechanical and clinical research yielded invaluable knowledge that led to important improvements in functional outcome and implant durability. Among these refinements were stronger polyethylene derivatives, better ingrowth technology, and improved connection devices. As the durability and longevity of implant technology increased, younger active patients became suitable candidates for this procedure. In fact, RSA has played a pivotal role in making shoulder arthroplasty the fastest growing implant technol...
Bringing together materials mechanics and modelling, this book provides a complete guide to damage mechanics of composite materials for engineers.
This work discusses the methodology and available evidence from systematic reviews on the current best practice in anaesthesia and analgesia. The first edition is built upon in this thoroughly revised and updated text. Contributions are from acknowledged world authorities on systematic review in the specialty. The free access website continues to provide added detail on the literature.
Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. Build your Foundation of Basic Science – from Research to Clinical Application A great tool for MOC preparation! A 'must have' for residency! This fourth edition, developed in a partnership between the American Academy of Orthopaedic Surgeons (AAOS) and the Orthopaedic Research Society (ORS), is your concise and clinically relevant resource for the diagnosis and treatment of musculoskeletal diseases and conditions.
From the New York Times–bestselling author of Seward and Stanton comes the definitive biography of John Jay: “Wonderful” (Walter Isaacson, New York Times–bestselling author of Leonardo da Vinci). John Jay is central to the early history of the American Republic. Drawing on substantial new material, renowned biographer Walter Stahr has written a full and highly readable portrait of both the public and private man—one of the most prominent figures of the late eighteenth and early nineteenth centuries. “The greatest founders—such as Washington and Jefferson—have kept even the greatest of the second tier of the nation’s founding generation in the shadows. But now John Jay, argu...
This book provides a roadmap for early-career scholars who seek to produce quality research that has a significant impact, within their chosen field and beyond.
War and Peace is widely viewed as one of the world's greatest novels, but oddly, no reader's companion to the text has yet been written in English. This volume will fill that gap. For scholars, it will synthesize the critical heritage and present new perspectives on the novel. For the general reader, it will provide the sort of guidance that will enrich their reading experience and help them navigate the long and rewarding journey to the novel's end. The annotations provide thorough background on the historical contexts, notes on the character and plot development, discussion of the various English translations, and other explanatory notes that will clarify the fundamental ideas and aesthetic devices of the novel.