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Statistical Issues in Drug Development
  • Language: en
  • Pages: 523

Statistical Issues in Drug Development

Drug development is the process of finding and producingtherapeutically useful pharmaceuticals, turning them into safe andeffective medicine, and producing reliable information regardingthe appropriate dosage and dosing intervals. With regulatoryauthorities demanding increasingly higher standards in suchdevelopments, statistics has become an intrinsic and criticalelement in the design and conduct of drug development programmes. Statistical Issues in Drug Development presents anessential and thought provoking guide to the statistical issues andcontroversies involved in drug development. This highly readable second edition has been updated toinclude: Comprehensive coverage of the design and in...

Dicing with Death
  • Language: en
  • Pages: 364

Dicing with Death

If you think that statistics has nothing to say about what you do or how you could do it better, then you are either wrong or in need of a more interesting job. Stephen Senn explains here how statistics determines many decisions about medical care, from allocating resources for health, to determining which drugs to license, to cause-and-effect in relation to disease. He tackles big themes: clinical trials and the development of medicines, life tables, vaccines and their risks or lack of them, smoking and lung cancer and even the power of prayer. He entertains with puzzles and paradoxes and covers the lives of famous statistical pioneers. By the end of the book the reader will see how reasoning with probability is essential to making rational decisions in medicine, and how and when it can guide us when faced with choices that impact on our health and even life.

Cross-over Trials in Clinical Research
  • Language: en
  • Pages: 364

Cross-over Trials in Clinical Research

Cross-over trials are an important class of design used in the pharmaceutical industry and medical research, and their use continues to grow. Cross-over Trials in Clinical Research, Second Edition has been fully updated to include the latest methodology used in the design and analysis of cross-over trials. It includes more background material, greater coverage of important statistical techniques, including Bayesian methods, and discussion of analysis using a number of statistical software packages. * Comprehensive coverage of the design and analysis of cross-over trials. * Each technique is carefully explained and the mathematics is kept to a minimum. * Features many real and original examples, taken from the author's vast experience. * Includes discussion of analysis using SAS, S-Plus and, GenStat, StatXact and Excel. * Written in a style suitable for statisticians and physicians alike. * Computer programs to accompany the examples in the book can be downloaded from the Web Primarily aimed at statisticians and researchers working in the pharmaceutical industry, the book will also appeal to physicians involved in clinical research and students of medical statistics.

The Mood Elevator
  • Language: en
  • Pages: 233

The Mood Elevator

Urging us to cultivate mental attitudes like curiosity and gratitude that will keep us on the higher floors, this practical book explains how to quiet the mind and nurture positive thoughts without succumbing to Pollyannaish denial. --

The Forum
  • Language: en
  • Pages: 314

The Forum

  • Type: Book
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  • Published: 1897
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  • Publisher: Unknown

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The Southeastern Reporter
  • Language: en
  • Pages: 1042

The Southeastern Reporter

  • Type: Book
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  • Published: 1888
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  • Publisher: Unknown

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Good Roads
  • Language: en
  • Pages: 898

Good Roads

  • Type: Book
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  • Published: 1895
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  • Publisher: Unknown

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Advance Bulletin of Interstate Commerce Acts Annotated
  • Language: en
  • Pages: 252
ICC Register
  • Language: en
  • Pages: 868

ICC Register

  • Type: Book
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  • Published: 1985
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  • Publisher: Unknown

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