Welcome to our book review site go-pdf.online!
You may have to Search all our reviewed books and magazines, click the sign up button below to create a free account.
Optical Polarimetric Modalities for Biomedical Research
This book focuses on polarization microscopy, a powerful optical tool used to study anisotropic properties in biomolecules, and its enormous potential to improve diagnostic tools for various biomedical research. The interaction of polarized light with normal and abnormal regions of tissue reveals structural information associated with its pathological condition. Diagnosis using conventional microscopy can be time-consuming, as pathologists require an hour to freeze and stain tissue slices from suspected patients. In comparison, polarization microscopy more quickly distinguishes abnormal tissue and provides better microstructural information of samples, even in the absence of staining. This b...
Phytochemical Genomics
This book provides a comprehensive reference for various plant bioactive compounds for research and pharmacological significance across the entire spectrum of phytochemical genomics. The book opens with general information on diversity, analysis and genomic basis of phytochemicals, computational approaches, databases for responsible genes, and biosynthetic pathways, and it delves very much into the details behind phytochemical diversity and diverse roles of plant metabolites. The later parts of the book also explore the direct drug discovery and omics approaches including metabolomics, transcriptomics, as well as gene editing technology experiments to further inspire readers into its unlimited potentials. Each chapter includes detailed analysis and relevant experiments for better and deeper understanding of the concepts. The book will be an invaluable aid for medicinal plant researchers and a rich source of information and advice for advanced undergraduates and graduates in the fields of medicine, nutraceuticals, cosmetics, flavor, and fragrance studies.
Role of the Transcriptome in Breast Cancer Prevention
This book will provide the latest advances in molecular and cellular biology for establishing the foundation of a complete understanding of the mechanisms of breast differentiation leading to cancer prevention. The authors are based on the epidemiological evidence indicating that early first full term pregnancy is a protective factor in human against breast cancer and they have used this paradigm and developed experimental systems in both in vivo and in vitro that have demonstrated mechanistically how the differentiation at the organ and cellular level takes place. This knowledge has provided the blueprint for developing better understanding of the basis of cancer prevention. The transcripto...
Infections and Pregnancy
This book is a complete guide to the diagnosis and management of any infectious disease which may affect the mother or the fetus during pregnancy. Pregnancy is a unique condition in which the interplay of endocrine and immune influences leads to altered severity and susceptibility to infectious diseases. These infections, in turn, are a substantial cause of maternal and perinatal morbidity. The book discusses the immunologic, clinical and epidemiologic evidence for altered responses during pregnancy. Several infections have unique consequences in pregnancy. Some infections have vertical transmission, and their management focuses on decreasing perinatal transmission. Others can be transmitted...
Novel Immune Markers and Predictive Models for Immunotherapy and Prognosis in Breast and Gynecological Cancers
Precision medicine is an emerging practice by which clinicians aim to deliver a personalized treatment program to affected patients based on information gained from their individual clinical and biological profiles. In the context of precise cancer immunotherapy, multi-omics, high-throughput sequencing, big data, and other approaches serve to screen new predictive factors for immunotherapy response and prognosis in cancer patients.
Recent Advances in Natural Products Science
This book provides a summarized information related to the global herbal drug market and its regulations, ethnopharmacology of traditional crude drugs, isolation of phytopharmaceuticals, phytochemistry, standardization, and quality assessment of crude drugs. Natural products science has constantly been developing with comprehensive data contemplating different parts of natural drugs, such as global trade, quality control and regulatory concerns, traditional medicine systems, production and utilization of drugs, and utilization of medicinal and aromatic plants. This broad information about crude drugs gives rise to a subject that is now recognized as advance natural products science. By conte...
Structural Variation of the Chloroplast Genome and Related Bioinformatics Tools
The plastid genome has been the most important source of data for the reconstruction of plant phylogeny and taxonomic studies. With the rapid advancement of sequencing technology and bioinformatics, it has become laboratory routine work for obtaining plastid genomes (plastome), and population studies can be performed using chloroplast genome data. However, plastid genomes with specific characters such as pseudogenes, gene losses, gene duplications, gene rearrangements, widespread intra-individual polymorphisms, large-scale horizontal gene transfer, etc. have not been systematically studied. For example, plastomes of several saprophytic plants were confirmed to have lost many photosynthesis genes. The IR region of some plants decreased to several hundred base pairs, disappears completely, increased by dozens of kb, or repeat in the same direction. Most of these chloroplast structural variations are related to import plant evolution or special environmental adaptation, but their mechanisms are still unclear and effective analytical tools are lacking.
Enzymatic Targets for Drug Discovery Against Alzheimer's Disease
The book summarizes the role of multiple enzyme targets and strategies to design and develop novel drug candidates for Alzheimer’s disease (AD). It brings together researchers across the globe having varied scientific backgrounds and expertise in a single volume. The chapters highlight current information scientists have unraveled about the origin, pathogenesis and prevention of AD. The contributions consider both established and emerging drug targets viz. Tau proteins, TREM, and microglia. Topics covered in the book include multi-target anti-Alzheimer's agents, epigenetic modifications, and the role of specific proteins like TMP21 and Tau in AD. A section dedicated to pharmacological trea...
Bisphenol A
Bisphenol A (BPA) is a high production volume endocrine-disrupting chemical present in numerous consumer products. Extensive use of BPA has led to wide-spread contamination in the air, soil, and water, leading to ubiquitous human exposure. Research into BPA has grown exponentially over the past ten years, with numerous modes of action being identified that impact human health and disease development. While BPA has estrogenic effects, emerging literature has identified several non-receptor mediated modes of action, such as epigenetic reprogramming, that can affect the long-term health of the population. This book highlights the multiple modes of action BPA can use to reprogram cells genetically and metabolically. By compiling critical studies in BPA and outlining the connections and disparities in the literature to build a broader understanding of this complex endocrine-disrupting chemical and its impact on the environment and human health, this book is an ideal resource for postgraduates and researchers in a range of disciplines from toxicology to epigenetics and cancer epidemiology.
