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AACR 2016: Abstracts 2697-5293
  • Language: en
  • Pages: 1518

AACR 2016: Abstracts 2697-5293

The AACR Annual Meeting is a must-attend event for cancer researchers and the broader cancer community. This year's theme, "Delivering Cures Through Cancer Science," reinforces the inextricable link between research and advances in patient care. The theme will be evident throughout the meeting as the latest, most exciting discoveries are presented in every area of cancer research. There will be a number of presentations that include exciting new data from cutting-edge clinical trials as well as companion presentations that spotlight the science behind the trials and implications for delivering improved care to patients. This book contains abstracts 2697-5293 presented on April 19-20, 2016, at the AACR Annual Meeting.

Mitochondria: The Anti- cancer Target for the Third Millennium
  • Language: en
  • Pages: 387

Mitochondria: The Anti- cancer Target for the Third Millennium

  • Type: Book
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  • Published: 2014-05-26
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  • Publisher: Springer

This book will be focused on mitochondria as very promising targets for anti-cancer drugs, yet to be fully exploited. It will contain chapters focused on aspects of basic research as well as on clinical relevance, which will be written by specialists in the field. That the role of mitochondria in human pathologies goes beyond the neoplastic diseases will be documented by a chapter of the role of mitochondria in Friedreich's ataxia.

AACR 2019 Proceedings: Abstracts 1-2748
  • Language: en
  • Pages: 2881

AACR 2019 Proceedings: Abstracts 1-2748

American Association for Cancer Research 2019 Proceedings: Abstracts 1-2748 - Part A

Redox-Genome Interactions in Health and Disease
  • Language: en
  • Pages: 664

Redox-Genome Interactions in Health and Disease

  • Type: Book
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  • Published: 2003-09-12
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  • Publisher: CRC Press

At the nexus of advances in molecular genetics and findings in redox biology, this volume elaborates on the dynamics governing cellular redox states and aggregates the body of evidence linking oxidative stress and redox modulation with a host of monogenetic and polygenetic diseases.

Essentials of Apoptosis
  • Language: en
  • Pages: 745

Essentials of Apoptosis

This is the second edition of the comprehensive, concise summary of apoptosis research. It covers the major concepts, molecular architecture, the biochemical pathways, and pathophysiological significance of apoptosis. This book provides a guideline of standard biochemical and cell biologic approaches to apoptosis bench work with an emphasis on translational clinical applications for immune disorders, cancer research, ischemia, and neuronal degeneration. Since the original publication in 2003, the apoptosis field has expanded rapidly – chapters not only need to be revised and expanded, but there is a need for all new chapters covering exciting advances in bioinformatics, systems biology, oxidative stress, etc.

Free Radicals in Biology and Medicine
  • Language: en
  • Pages: 961

Free Radicals in Biology and Medicine

Free Radicals in Biology and Medicine has become a classic text in the field of free radical and antioxidant research. Now in its fifth edition, the book has been comprehensively rewritten and updated whilst maintaining the clarity of its predecessors. Two new chapters discuss 'in vivo' and 'dietary' antioxidants, the first emphasising the role of peroxiredoxins and integrated defence mechanisms which allow useful roles for ROS, and the second containing new information on the role of fruits, vegetables, and vitamins in health and disease. This new edition also contains expanded coverage of the mechanisms of oxidative damage to lipids, DNA, and proteins (and the repair of such damage), and t...

Cell Death Regulation in Health and Disease - Part B
  • Language: en
  • Pages: 230

Cell Death Regulation in Health and Disease - Part B

Cell Death Regulation in Health and Disease - Part B, Volume 352, the latest release in the International Review of Cell and Molecular Biology, reviews and details current advances in cell and molecular biology. Chapters in this updated release include Regulation of cell death signaling in insects, Bcl-2 family proteins, Cell death signaling in prokaryotes, Parthanatos in neurodegenerative diseases, Cell death regulation in yeast, Mutual regulation of autophagy and necroptosis, Therapeutic inhibition of cell death by autophagy induction, and Necroptosis in neurodegenerative diseases.

Herbal and Traditional Medicine
  • Language: en
  • Pages: 862

Herbal and Traditional Medicine

  • Type: Book
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  • Published: 2004-08-30
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  • Publisher: CRC Press

Responding to the increased popularity of herbal medicines and other forms of complementary or alternative medicine in countries around the world, this reference reviews and evaluates various safety, toxicity, and quality-control issues related to the use of traditional and herbal products for health maintenance and disease prevention and treatment. With over 3,550 current references, the book highlights the role of herbal medicine in national health care while providing case studies of widely used herbal remedies and their effects on human health and wellness and the need for the design and performance of methodologically sound clinical trials for the plethora of herbal medicines.

Novel Chemotherapeutic Agents: Preactivation in the Treatment of Cancer and AIDS
  • Language: en
  • Pages: 269

Novel Chemotherapeutic Agents: Preactivation in the Treatment of Cancer and AIDS

This book is about a discovery termed "preactivation" that is considered a major breakthrough in photodynamic therapy and in drug development. The process of preactivation generates previously unknown chemotherapeutic agents that are not only effective against malignancies and viral infections, but are also easily tolerated.

Micronutrients and Brain Health
  • Language: en
  • Pages: 444

Micronutrients and Brain Health

  • Type: Book
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  • Published: 2009-10-06
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  • Publisher: CRC Press

Micronutrients and Brain Health addresses cutting-edge research related to processes of oxidative stress that affect brain function, an area of increasing significance for those concerned and involved with public health and translational medicine. Edited by four leading micronutrient researchers, the book brings together the investigative work of m