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The Ancestry of Frances Maria Goodman, 1829-1912
Frances Maria Goodman was born 28 July 1829 in Boston. Her parents were William Goodman and Margaret Adams. Her grandparents were Moses Goodman, Amy Seymour, Samuel Adams and Margaret Austin. She married Learner Blackman Harrison in Cincinnati, Ohio in 1853. Ancestors and relatives lived mainly in England, New England and Virginia.
How Tobacco Smoke Causes Disease
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
