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Epstein-Barr virus (EBV)-associated T/NK-cell lymphoproliferative diseases (EBV-T/ NK-LPDs) are a group of mostly neoplastic diseases of unknown etiology. These diseases are characterized by ectopic infection of EBV in T or NK cells, that are unusual cellular targets for the B-lymphotropic virus. Multiple entities of EBV-T/ NK-LPDs can be diagnosed in a single patient and one entity of EBV-T/NK-LPDs may evolve into another during the clinical course, suggesting a common mechanism in the pathogenesis, including a genetic predisposition. Treatment of these diseases is difficult and often requires hematopoietic stem cell transplantation. The research topic “Epstein-Barr virus-associated T/NK-...
Presents the broad outline of NIH organizational structure, theprofessional staff, and their scientific and technical publications covering work done at NIH.
According to author Harvey Bialy, the work of molecular biologist Peter Duesberg has been grossly distorted by the media and scientific establishments. Until recently, the scientific community--and most notably, those from the National Institute for Health--have been unwilling to look at his provocative theories of different causes for cancer and HIV/AIDS. Inspired by UC Berkeley's rare creation of an archive for Duesberg's papers, this book explores Duesberg's early groundbreaking work with viruses and oncogenes, his contentious fights with other scientists, and the profound influence of his life's work.
Over the last several years the field of humanized mice has matured and developed into an essential component of translational research for HIV/AIDS. Humanized mice serve both as vehicles for discovery and as highly sophisticated platforms for biomedical research. In addition, humanized mice have demonstrated outstanding potential for the investigation of critical aspects of the infection and pathogenesis of the hepatitis and herpes viruses, as well as highly relevant microbial infections such as tuberculosis and malaria. Humanized Mice for HIV Research provides a comprehensive presentation of the history, evolution, applications, and current state of the art of this unique animal model. An ...
The early, organ-specific diagnosis of malignancy continues to be a major unmet medical need. Clearly the ability to establish an early diagnosis of cancer is dependent upon an intimate knowledge of the cancer's biology, which if understood at the molecular level should identify key diagnostic and therapeutic manipulation points. Advances in recombinant gene technology have provided significant understanding of the mechanisms of action of oncogenic viruses, as well as of cancer-associated genomic sequences (onco genes). This text will explore the known molecular genetic, biolog ical, and clinical knowledge of selected human neoplasms that demonstrate association with suspected oncogenic viru...
"This index contains a comprehensive listing of more than 20,000 Japanese swordsmiths, from the early days right down to modern times, i.e. from kotô to shinsakutô. It is not simply a list of names, it also provides biographical information according to the extent of a smith's fame. Aim is to give the reader a coherent picture of a certain smith, that means his civilian name, how did he sign, in which style did he work, and who was his master or his school environment. Thereby, the most common theories on a smith are included and discrepancies in the transmissions are pointed out. This work is a revised and completely new recorded list of smiths by incorporating all relevant Japanese and non-Japanese sources. Incorrect entries and double listings were deleted and readings corrected. The smiths are listed in alphabetical order and sorted according to their used characters. A list of all characters used in the names of the smiths in this index is available, sorted by stroke order, so that the search of a smith with an unknown reading is also possible."--Back cover.
The latest volume in this series covers recent research in molecular biology and biochemistry. It provides information on such rapidly expanding areas as manipulating monoclonal antibodies, diseases of abnormal antigen receptor formation, and the molecular mechanisms of autoimmunity. It will be useful to researchers in molecular biology, immunology, and biochemistry who need to keep up with new developments in this field.
This volume provides coverage of many diverse areas of molecular neurobiology and pharmacology. It includes information on recent advances in the understanding of memory formation, sensory perception, neurological diseases, and the controversial area of neural transplantation. this unique volume is of use to specialists in this field as well as researchers in a wide variety of other areas who need a convenient source of recent developments.