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Principles of Statistical Genomics
Statistical genomics is a rapidly developing field, with more and more people involved in this area. However, a lack of synthetic reference books and textbooks in statistical genomics has become a major hurdle on the development of the field. Although many books have been published recently in bioinformatics, most of them emphasize DNA sequence analysis under a deterministic approach. Principles of Statistical Genomics synthesizes the state-of-the-art statistical methodologies (stochastic approaches) applied to genome study. It facilitates understanding of the statistical models and methods behind the major bioinformatics software packages, which will help researchers choose the optimal algorithm to analyze their data and better interpret the results of their analyses. Understanding existing statistical models and algorithms assists researchers to develop improved statistical methods to extract maximum information from their data. Resourceful and easy to use, Principles of Statistical Genomics is a comprehensive reference for researchers and graduate students studying statistical genomics.
Mobile Ad-hoc and Sensor Networks
This book constitutes the refereed proceedings of the Third International Conference on Mobile Ad-hoc and Sensor Networks, MSN 2007, held in Beijing, China, in December 2007. The papers address all current issues in mobile ad hoc and sensor networks and are organized in topical sections on routing, network protocols, energy efficiency, data processing, self-organization and synchronization, deployment and application, as well as security.
Quantitative Genetics
The intended audience of this textbook are plant and animal breeders, upper-level undergraduate and graduate students in biological and agricultural science majors. Statisticians who are interested in understanding how statistical methods are applied to genetics and agriculture can benefit substantially by reading this book. One characteristic of this textbook is represented by three chapters of technical reviews for Mendelian genetics, population genetics and preliminary statistics, which are prerequisites for studying quantitative genetics. Numerous examples are provided to illustrate different methods of data analysis and estimation of genetic parameters. Along with each example of data analyses is the program code of SAS (statistical analysis system).
Mutation and Evolution
Although debated since the time of Darwin, the evolutionary role of mutation is still controversial. In over 40 chapters from leading authorities in mutation and evolutionary biology, this book takes a new look at both the theoretical and experimental measurement and significance of new mutation. Deleterious, nearly neutral, beneficial, and polygenic mutations are considered in their effects on fitness, life history traits, and the composition of the gene pool. Mutation is a phenomenon that draws attention from many different disciplines. Thus, the extensive reviews of the literature will be valuable both to established researchers and to those just beginning to study this field. Through up-...
Evolutionary Computation, Machine Learning and Data Mining in Bioinformatics
This book constitutes the refereed proceedings of the 7th European Conference on Evolutionary Computation, Machine Learning and Data Mining in Bioinformatics, EvoBIO 2009, held in Tübingen, Germany, in April 2009 colocated with the Evo* 2009 events. The 17 revised full papers were carefully reviewed and selected from 44 submissions. EvoBio is the premiere European event for experts in computer science meeting with experts in bioinformatics and the biological sciences, all interested in the interface between evolutionary computation, machine learning, data mining, bioinformatics, and computational biology. Topics addressed by the papers include biomarker discovery, cell simulation and modeling, ecological modeling, uxomics, gene networks, biotechnology, metabolomics, microarray analysis, phylogenetics, protein interactions, proteomics, sequence analysis and alignment, as well as systems biology.
Pattern Recognition in Bioinformatics
This book constitutes the refereed proceedings of the 6th International Conference on Pattern Recognition in Bioinformatics, PRIB 2011, held in Delft, The Netherlands, in November 2011. The 29 revised full papers presented were carefully reviewed and selected from 35 submissions. The papers cover the wide range of possible applications of bioinformatics in pattern recognition: novel algorithms to handle traditional pattern recognition problems such as (bi)clustering, classification and feature selection; applications of (novel) pattern recognition techniques to infer and analyze biological networks and studies on specific problems such as biological image analysis and the relation between sequence and structure. They are organized in the following topical sections: clustering, biomarker selection and classification, network inference and analysis, image analysis, and sequence, structure, and interactions.
Poultry Genetics, Breeding and Biotechnology
Annotation. In this comprehensive research book issues associated with poultry breeding are addressed, by examining quantitative and molecular genetics and the uses of transgenic technology. The important area of disease resistance and transmission is also covered in a special section looking at the genetics of disease resistance. This book represents the first complete integration of our current knowledge of biotechnology and quantitative and molecular genetics as applied to poultry breeding.
Quantitative Trait Loci
In Quantitative Trait Loci: Methods and Protocols, a panel of highly experienced statistical geneticists demonstrate in a step-by-step fashion how to successfully analyze quantitative trait data using a variety of methods and software for the detection and fine mapping of quantitative trait loci (QTL). Writing for the nonmathematician, these experts guide the investigator from the design stage of a project onwards, providing detailed explanations of how best to proceed with each specific analysis, to find and use appropriate software, and to interpret results. Worked examples, citations to key papers, and variations in method ease the way to understanding and successful studies. Among the cutting-edge techniques presented are QTDT methods, variance components methods, and the Markov Chain Monte Carlo method for joint linkage and segregation analysis.
Plant Breeding Reviews, Volume 22
Plant Breeding Reviews, Volume 22 presents state-of-the-art reviews on plant genetics and the breeding of all types of crops by both traditional means and molecular methods. The emphasis of the series is on methodology, a practical understanding of crop genetics, and applications to major crops.
Evolution Algebras and Their Applications
Behind genetics and Markov chains, there is an intrinsic algebraic structure. It is defined as a type of new algebra: as evolution algebra. This concept lies between algebras and dynamical systems. Algebraically, evolution algebras are non-associative Banach algebras; dynamically, they represent discrete dynamical systems. Evolution algebras have many connections with other mathematical fields including graph theory, group theory, stochastic processes, dynamical systems, knot theory, 3-manifolds, and the study of the Ihara-Selberg zeta function. In this volume the foundation of evolution algebra theory and applications in non-Mendelian genetics and Markov chains is developed, with pointers to some further research topics.
