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Thyroid nodules have a high prevalence in populations where iodine deficiency rates are high and in people older than 50 years. Considering that only 5-10% of thyroid nodules are of malignant nature, it is apparent that the clinical issue is the cost-effective differential diagnosis between benign nodules and the malignant ones. This e-book addresses this key issue by giving readers a general overview on the clinical aspect of thyroid nodules and specific details on molecular characterization of the nodules. This e-book is particularly suitable for novice endocrinologists but laboratory biologists and technicians involved in the pre-surgical diagnosis of thyroid cancer can also benefit from the additional technical details offered in this text.
Endothelial cell biology has developed into a vibrant discipline and has become a critical instrument to study several disease processes on the cellular and molecular level. It is now widely recognized that dysfunctions of normal endothelial cell homeostasis are involved in some of the most important human diseases, including ischemic heart diseases, hypertension, atherosclerosis, tumors, diabetes, arthritis, and inflammation. Further, the increasing importance and recognition of the field of vascular biology in general requires in vitro and in vivo techniques in order to address the complex questions. Methods in Endothelial Cell Biology is a comprehensive practical "how-to"-guide summarizing the most relevant established techniques as well as a number of new emerging techniques. Easy-to-follow reliable protocols provide a useful lab bench resource for the experienced researcher and newcomer to the field.
This book is a printed edition of the Special Issue "Current Knowledge in Thyroid Cancer—From Bench to Bedside" that was published in IJMS
Genetic Diagnosis of Endocrine Disorders, Second Edition provides users with a comprehensive reference that is organized by endocrine grouping (i.e., thyroid, pancreas, parathyroid, pituitary, adrenal, and reproductive and bone), discussing the genetic and molecular basis for the diagnosis of various disorders. The book emphasizes the practical nature of diagnosing a disease, including which tests should be done for the diagnosis of diabetes mellitus in adults and children, which genes should be evaluated for subjects with congenital hypothyroidism, which genetic tests should be ordered in obese patients or for those with parathyroid carcinoma, and the rationale behind testing for multiple endocrine neoplasias. - Offers a clear presentations of pharmacogenetics and the actual assays used in detecting endocrine diseases - Teaches the essentials of the genetic basis of disease in each major endocrine organ system - Offers expert advice from genetic counselors on how to use genetic information in counseling patients - Includes new chapters on the genetics of lipid disorders and glycogen storage diseases, genetics of hypoglycemia, and whole genome/exome sequencing
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No es aventurado afirmar que la mayoría de los chilenos ha escuchado al menos una vez, y es posible que muchas veces, la voz de Silvia Infantas. Como tampoco es arriesgado aseverar que esa misma mayoría la ha oído cantar sin saber a quién pertenece esa voz. Es casi una garantía: Silvia Infantas será escuchada con certeza, y a gran escala, al menos una vez al año en nuestro país. Su canto, cuando lleguen las fiestas dieciocheras, se oirá en fondas y ramadas, en programas de radio y matinales de televisión, pero además en el sonido ambiente de restaurantes y malls, en ascensores y pasillos de supermercado, en salas de espera y música de centrales telefónicas, en ceremonias municip...
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