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Annual Reports in Medicinal Chemistry
Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies. Sections I-IV are disease orientated and generally report on specific medicinal agents. Sections V and VI continue to emphasize important topics in medicinal chemistry, biology, and drug design. Section VII looks at Trends and Perspectives in the pharmaceuticals market. Critical reviews of the previous year's literature in many topics of interest to medicinal chemists Highlights major developments in medicinal chemistry Includes a comprehensive set of cumulative indices to easily locate topics in all published volumes
40 Years of Experience with the National Market System (NMS)
In 1975, the U.S. Securities Acts Amendments were enacted by Congress, which amongst other measures, officially mandated development of a National Market System (NMS). Since that time, the competitive map has been redrawn, technological changes have been huge and pervasive in scope, and the landscape is ever-changing. This book looks at the evolution of NMS and the factors that have influenced it since its development. Titled after the Baruch College Financial Markets Conference, 40 Years of Experience with the National Market System (NMS): Who Are the Winners and What Have We Learned, the book examines the following questions: What is liquidity and how is it best measured and provided? Has ...
Annual Reports in Medicinal Chemistry
Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies. - Covers findings related to cardiovascular, inflammation, and pulmonary diseases - Examines issues in oncology, from mTor inhibitors to drug targets - Incorporates up-to-date information on drug design and discovery, including delivery to market
Organometallic Chemistry
Organometallic chemistry is an interdisciplinary science which continues to grow at a rapid pace. Although there is continued interest in synthetic and structural studies the last decade has seen a growing interest in the potential of organometallic chemistry to provide answers to problems in catalysis synthetic organic chemistry and also in the development of new materials. This Specialist Periodical Report aims to reflect these current interests reviewing progress in theoretical organometallic chemistry, main group chemistry, the lanthanides and all aspects of transition metal chemistry. Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major ...
Progress in Medicinal Chemistry
The perceived lack of drug discovery productivity in recent times has led to much debate in the pharmaceutical/biotechnology industry as escalating R&D costs are not being matched by increased output. Few observers doubt that selecting the right targets, ie those which are critical to disease pathology and are 'druggable', is the best starting point for improved productivity.The seven chapters of this volume describe recent progress towards drugs acting at a range of 'druggable' targets. One chapter addresses kinases, one covers an ion channel, two proteases are featured and three of the chapters cover G-protein coupled receptors, which has historically perhaps been the most fruitful area for medicinal chemists.*Presents the latest research in the field of drug discovery *Publishes on an annual basis to bring you the most innovative updates in medicinal chemistry *Available as an online resource via ScienceDirect
Nuclear Magnetic Resonance
As a spectroscopic method, Nuclear Magnetic Resonance (NMR) has seen spectacular growth over the past two decades, both as a technique and in its applications. Today the applications of NMR span a wide range of scientific disciplines, from physics to biology to medicine. Each volume of Nuclear Magnetic Resonance comprises a combination of annual and biennial reports which together provide comprehensive of the literature on this topic. This Specialist Periodical Report reflects the growing volume of published work involving NMR techniques and applications, in particular NMR of natural macromolecules which is covered in two reports: "NMR of Proteins and Acids" and "NMR of Carbohydrates, Lipids...
Drug Discovery for Psychiatric Disorders
This is a wide scope and in-depth coverage of the state of the art and future directions in drug discovery for major psychiatric disorders.
Predicting and Trading the News
Trading does not need to be complicated. This book intends to show the reader how a relatively simple approach to reading price action at key levels can be used for trading the news, as well as non-news trading, with some remarkable profits in very quick time. There are plenty of chart examples, showing real trades as well as theoretical ones; even some where the trades didn’t work out. You can trade almost any instrument that’s likely to be moved by a scheduled news event; be it forex, indices, crypto or commodities. Timing is key: when you can enter a trade before the news is released, from seconds before to hours before, your risk to reward will often be multiplied many times over, compared to waiting for the data to be published. When you can’t enter before the stats are known, or price does the opposite to expectations, there are ways to get in on the dominant move to reap the rewards.
Neuropeptide Y and Related Peptides
After a little more than 20 years since the original discovery of neuropeptide Y (NPY) by Tatemoto and colleagues, the field of NPY research has made remarkable progress and is coming of age.The present volume addresses all major topics in connection with NPY and related peptides by established leaders in their respective areas. Experienced NPY-aficionados will certainly find new and useful additional information in this volume and newcomers to the field will hopefully discover how much exciting research this still has to offer.
High Pressure Chemistry
It is a basic law of chemistry that pressure influences reactions. Thus, high-pressure reactions are no longer a rarity in chemistry today, but rather are indispensable tools - whether for innovative syntheses, new products or for explaining reaction mechanisms. The expert editors, Rudi van Eldik and Frank-Gerrit Klärner, provide a comprehensive overview of this fascinating field, ranging from the influence of high pressure on organic and inorganic reactions, via concrete applications in synthesis for metal catalytic and stereoselective processes right up to the use of supercritical liquids. Written by renowned experts, this volume contains a wealth of vital and practical information, for both newcomers to the field as well as experienced high-pressure chemists. Whether in academia or industry, this book belongs on the shelf of every chemist concerned with high-pressure chemistry either now or in the future.
