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The author makes a unique contribution to the field by discussing the history and philosophy of the neurosciences, and then developing critical approaches which integrate techniques, theory, and ethics. Taken as a whole, Jacobson's work will provide a coherent and humane framework for future research programs. The paperback edition of this highly successful text, first published in 1993, is now available! The author brings the ethics of neuroscience into a closer relationship with empirical research. Covering the field's history, philosophy, theories, and techniques, this volume provides the necessary moral and ethical framework to evaluate neuroscience research.
This consistent and well-illustrated text is an up-to-date survey of cellular and molecular events contributing to the assembly of the vertebrate nervous system. Chapters include a mixture of historical content and descriptions from literature that best illustrate specific aspects of development.
The origins of this book go back to the first electron microscopic studies of the central nervous system. The cerebellar cortex was from the first an object of close study in the electron microscope, repeating in modern cytology and neuroanatomy the role it had in the hands of RAMON y CAJAL at the end of the nineteenth century. The senior author vividly remembers a day early in 1953 when GEORGE PALADE, with whom he was then working, showed him an electron micrograph of a cerebellar glomerulus, saying "That is what the synapse should look like. " It is true that the tissue was swollen and the mitochondria were exploded, but all of the essentials of synaptic structure were visible. At that tim...
This book represents the most complete and authoritative description on the fine structure of the nervous system available in a single volume. Beginning with background material on the neuron, the book then examines specific portions of the nerve cell, and of the various supporting cells. Structure is first described in a general fashion, followed by detailed coverage of the fine structure of each component, with full discussion of how the structural features relate to their functions. Extensively revised and rewritten, this book will bring readers up to date with the many important developments that have taken place since publication of the previous edition. It includes over 130 electron micrographs and line drawings, many of which are new to this edition.
International Review of Cytology
This book encompasses basic and clinical reports on the cerebellum and its primary atrophic disorders, the cerebellar degenerations. Rapid progress has been made in undestanding the organization and function of the cerebellum at the neuronal, synaptic, and molecular level. Of particular importance has been the identification of the chemical transmitters utilized by the cer ebellar cellular systems. More than any other brain region, the cerebellum utilizes amino acids as its main excitatory and inhibitory neurotransmitters. Excitatory amino acid transmitters, in addition to serving neuronal com munication, may also mediate trophic and toxic effects, and as such, they may playa role in neurode...
This is a fascinating collection of personal accounts which is a "must read" for anyone interested in membrane transport or the history of the development of the current picture of membrane transport physiology. This delightful book could serve variously as a history for investigators and historians or as a textbook for advanced students. No biology or medical library should be without it