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Statistical Analysis of Next Generation Sequencing Data
Next Generation Sequencing (NGS) is the latest high throughput technology to revolutionize genomic research. NGS generates massive genomic datasets that play a key role in the big data phenomenon that surrounds us today. To extract signals from high-dimensional NGS data and make valid statistical inferences and predictions, novel data analytic and statistical techniques are needed. This book contains 20 chapters written by prominent statisticians working with NGS data. The topics range from basic preprocessing and analysis with NGS data to more complex genomic applications such as copy number variation and isoform expression detection. Research statisticians who want to learn about this grow...
Advances on Theoretical and Methodological Aspects of Probability and Statistics
At the International Indian Statistical Association Conference, held at McMaster University in Ontario, Canada, participants focused on advancements in theory and methodology of probability and statistics. This is one of two volumes containing invited papers from the meeting. The 32 chapters deal with different topics of interest, including stochastic processes and inference, distributions and characterizations, inference, Bayesian inference, selection methods, regression methods, and methods in health research. The text is ideal for applied mathematicians, statisticians, and researchers in the field.
Statistical Methods for Ranking Data
This book introduces advanced undergraduate, graduate students and practitioners to statistical methods for ranking data. An important aspect of nonparametric statistics is oriented towards the use of ranking data. Rank correlation is defined through the notion of distance functions and the notion of compatibility is introduced to deal with incomplete data. Ranking data are also modeled using a variety of modern tools such as CART, MCMC, EM algorithm and factor analysis. This book deals with statistical methods used for analyzing such data and provides a novel and unifying approach for hypotheses testing. The techniques described in the book are illustrated with examples and the statistical software is provided on the authors’ website.
Progress in Autism Research
This book brings together the latest research in the battle against autism. According to numerous news reports, the increase in special needs children has reached epidemic proportions. Autism is a complex developmental disability that typically appears during the first three years of life. The result of a neurological disorder that affects the functioning of the brain, autism and its associated behaviours have been estimated to occur in as many as 2 to 6 in 1,000 individuals. Autism is four times more prevalent in boys than girls and knows no racial, ethnic, or social boundaries. Autism is a spectrum disorder. The symptoms and characteristics of autism can present themselves in a wide variety of combinations, from mild to severe. Although autism is defined by a certain set of behaviours, children and adults can exhibit any combination of the behaviours in any degree of severity. People with autism process and respond to information in unique ways. In some cases, aggressive and/or self-injurious behaviour may be present.
Strength in Numbers: The Rising of Academic Statistics Departments in the U. S.
Statistical science as organized in formal academic departments is relatively new. With a few exceptions, most Statistics and Biostatistics departments have been created within the past 60 years. This book consists of a set of memoirs, one for each department in the U.S. created by the mid-1960s. The memoirs describe key aspects of the department’s history -- its founding, its growth, key people in its development, success stories (such as major research accomplishments) and the occasional failure story, PhD graduates who have had a significant impact, its impact on statistical education, and a summary of where the department stands today and its vision for the future. Read here all about how departments such as at Berkeley, Chicago, Harvard, and Stanford started and how they got to where they are today. The book should also be of interests to scholars in the field of disciplinary history.
Advances in Survival Analysis
Handbook of Statistics: Advances in Survival Analysis covers all important topics in the area of Survival Analysis. Each topic has been covered by one or more chapters written by internationally renowned experts. Each chapter provides a comprehensive and up-to-date review of the topic. Several new illustrative examples have been used to demonstrate the methodologies developed. The book also includes an exhaustive list of important references in the area of Survival Analysis. - Includes up-to-date reviews on many important topics - Chapters written by many internationally renowned experts - Some Chapters provide completely new methodologies and analyses - Includes some new data and methods of analyzing them
Monte Carlo and Quasi-Monte Carlo Methods 2010
This book represents the refereed proceedings of the Ninth International Conference on Monte Carlo and Quasi-Monte Carlo Methods in Scientific Computing that was held at the University of Warsaw (Poland) in August 2010. These biennial conferences are major events for Monte Carlo and the premiere event for quasi-Monte Carlo research. The proceedings include articles based on invited lectures as well as carefully selected contributed papers on all theoretical aspects and applications of Monte Carlo and quasi-Monte Carlo methods. The reader will be provided with information on latest developments in these very active areas. The book is an excellent reference for theoreticians and practitioners interested in solving high-dimensional computational problems arising, in particular, in finance and statistics.
