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This concise book explains how to analyze endoscopic mucosal biopsies of the colon obtained for diagnosis and follow up of colitis in general and inflammatory bowel diseases (ulcerative colitis, Crohn’s disease and microscopic colitis) in particular. This is achieved by the presentation of basic lesions in multiple drawings together with an explanatory text and microscopic photographs. The description is completed by a review of various differential diagnostic issues and types of colitis. Colitis: A Practical Approach to Colon Biopsy Interpretation is aimed at general pathologists and pathologists in training and also gastroenterologists to help them understand how a precise diagnosis can be reached.
Metal ions in the brain are a necessity as well as a poison. The presence of metal ions in the active sites of biological catalysts or metalloproteins and in the biological functioning of nucleic acids is very well documented and they are required for brain activity. On the other hand, metals are very effective in generating oxidative stress. This effect does not only play a role in immunology but also is the root of practically all neurodegenerative disorders by inducing disease via the death of neurons. Managing metal ions in the brain could therefore be an important strategy in the search for therapeutic agents used in the treatment of neurodegenerative diseases. This new title gives an overview to key topics in the area of metal ions in the brain. It focuses on the role of metal ions in neurological systems by describing their advantageous functions as well as their poisonous features. It is therefore of interest for scientists in biochemistry and biophysics, physiology, toxicology as well as for physicians focused on this topic.
The traditional approach to kidney disorders is changing. In the field of diagnostics much innovative research is ongoing: from the “old” embryology, revisited and re-interpreted with new eyes in the light of immunohistochemistry, up to metabolomics the latest “daughter” of genomics, the most promising and remarkable of the “omics” disciplines. Between these two extremes we find a universe of novelties, ranging from the most recent urinary biomarkers to the questions of nutrition and growth, as well as those of ethics, which the new populations of extremely low birth weight (ELBW) neonates present to neonatologists and nephrologists. The studies on perinatal programming expands t...
This volume provides a comprehensive, state-of-the art review in the field of experimental and human nephrogenesis. The book reviews new data on the effects on kidney development by neonatal asphyxia, obstructive uropathies, nephrotoxic drugs, malnutrition, underfeeding, overfeeding and provides all possible preventive measures to ensure the well-being of the kidney at birth. The book also discusses the possible implications between renal development and the insurgence of kidney disease in adult life and the correlation with renal carcinogenesis. Written by well recognized experts in their fields, Kidney Development in Renal Pathology is a valuable tool for pathologists, neonatologists, nephrologists, gynecologists and researchers with an interest in kidney diseases.
Frontiers in Clinical Drug Research - Alzheimer Disorders is an e-Book series concerned with Alzheimer's disease (AD) that causes dementia, or loss of brain function. The disease affects the parts of the brain that deal with memory, thought, and language. Chapters in each volume focus on (Alzheimer Disorders) drug research with special emphasis on clinical trials, research on drugs in advanced stages of development and cure for Alzheimer’s disease and related disorders. Frontiers in Clinical Drug Research - Alzheimer Disorders will be of particular interest to readers interested in drug therapy this specific neurodegenerative condition and related brain disorders as the series provides relevant reviews written by experts in field of Alzheimers Disease research.
Join "Mr. Aluminum," a scientist who has made the study of aluminum his life's work, on a journey of discovery, reflection, and the science of aluminum. Professor Christopher Exley is a firm believer that science is only useful when it is properly communicated. Scientific papers are difficult vehicles for the wider communication of science and thus he has always endeavored to tell the story of his scientific research as widely as possible through myriad blogs, presentations, and interviews. Through a series of easy-reading entries written for non-scientists, Exley will educate readers about his lifelong scientific passion: aluminum. In scientific circles, aluminum—in relation to human heal...
The subject of aluminium and Alzheimer's disease has been plagued with controversy. This controversy has served to obscure much of the scientific research in this field, and subsequently has obscured the possibility that aluminium is a contributory factor in the aetiology of Alzheimer's disease. This book brings together many of the world's leading scientists researching aluminium and life and contains their critical summaries on the known facts about aluminium toxicity in man and to offer an opinion on the implications of this knowledge on a link between aluminium and Alzheimer's disease. The subject areas of the chapters were chosen to reflect the myriad of ways that aluminium is known to ...
The Toxicology Handbook 2e is a practical, didactic guide to the approach, assessment and management of poisoned patients. It has been written for hospital-based doctors at all levels and describes the risk assessment-based approach pioneered by the principal authors. the concise layout enables the reader to quickly locate information in a poisoning emergency. the book also features locally relevant information on bites, stings and envenoming. This book will also be useful for ambulance service paramedics and pharmacists.
Geriatric Psycho-Oncology is a comprehensive handbook that provides best practice models for the management of psychological, cognitive, and social outcomes of older adults living with cancer and their families. Chapters cover a wide range of topics including screening tools and interventions, psychiatric emergencies and disorders, physical symptom management, communication issues, and issues specific to common cancer sites. A resource section is appended to provide information on national services and programs. This book features contributions from experts designed to help clinicians review, anticipate and respond to emotional issues that often arise in the context of treating older cancer patients. Numerous cross-references and succinct tables and figures make this concise reference easy to use. Geriatric Psycho-Oncology is an ideal resource for helping oncologists and nurses recognize when it may be best to refer patients to their mental health colleagues and for those who are establishing or adding psychosocial components to existing clinics.
Geared to primary care practitioners, The Washington Manual® of Outpatient Internal Medicine focuses on common ambulatory medical problems encountered in each medical subspecialty. The book has a quick-reference format similar to The Washington Manual® of Medical Therapeutics, with a standard chapter template, a bulleted style, numerous tables and figures, and a two-color design. All chapters are written by house staff and faculty at Barnes-Jewish Hospital and Washington University School of Medicine. Coverage includes the traditional internal medicine subspecialties and other areas where problems are frequently seen in the ambulatory setting, such as dermatology, neurology, ophthalmology, otolaryngology, and psychiatry. Most subspecialties have separate symptom- and disease-based chapters. The Washington Manual® is a registered mark belonging to Washington University in St. Louis to which international legal protection applies. The mark is used in this publication by LWW under license from Washington University.