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This IBM® Redbooks® publication describes important networking concepts and industry standards that are used to support high availability on IBM System z®. Some of the networking standards described here are VLANs, VLAN trunking, link aggregation, virtual switches, VNICs, and load-balancing. We examine the various aspects of network setups and introduce the main Linux on System z networking commands and configuration files. We describe the management of network interface parameters, assignment of addresses to a network interface, and usage of the ifconfig command to configure network interfaces. We provide an overview of connectivity options available on the System z platform. We also des...
IBM® z/VM® 6.2 introduces significant changes to z/VM in the form of multi-system clustering technology allowing up to four z/VM instances in a single system image (SSI) cluster. This technology is important, because it offers clients an attractive alternative to vertical growth by adding new z/VM systems. In the past, this capability required duplicate efforts to install, maintain, and manage each system. With SSI, these duplicate efforts are reduced or eliminated. Support for live guest relocation (LGR) allows you to move Linux virtual servers without disruption to the business, helping you to avoid planned outages. The z/VM systems are aware of each other and can take advantage of their...
In this IBM® Redbooks® publication, we expand upon the concepts and experiences described in "An introduction to z/VM Single System Image (SSI) and Live Guest Relocation (LGR)", SG24-8006. An overview of that book is provided in Chapter 1, "Overview of SSI and LGR" on page 1. In writing this book, we re-used the same lab environment used in the first book, but expanded it to include IBM DB2® v10 on Linux on System z®, two IBM WebSphere® Application Server environments, and added a WebSphere application, used for performance benchmarking, which provided a workload that allowed us to observe the performance of the WebSphere Application Server during relocation of the z/VM® 6.2 member tha...
IBM® z/VM® 6.2 introduced significant changes to z/VM with a multi-system clustering technology that allows up to four z/VM instances in a single system image (SSI) cluster. This technology is important because it offers you an attractive alternative to vertical growth by adding new z/VM systems. In the past, this capability required duplicate efforts to install, maintain, and manage each system. With SSI, these duplicate efforts are reduced or eliminated. Support for live guest relocation (LGR) allows you to move Linux virtual servers without disrupting your business or incurring loss of service, thus reducing planned outages. The z/VM systems are aware of each other and take advantage of...
At the beginning of the last century, the development of the Neuroendocrine Concept sparked intensive and worldwide research efforts leading to fascinating insights into the complex and diverse system of neuroendocrine cells and its importance in human physiology and disease. Recent developments in new and expanding research areas, including developmental biology, regulation of angiogenesis, cellular signaling and transcription, and impressive results obtained by application of genomics and proteomics warranted a reevaluation of the neuroendocrine concept. impact of the current understanding of neuroendocrine biology and pathobiology in these research areas. In particular, new discoveries ar...
Targeted Nanomedicine for Breast Cancer Therapy provides a compilation of treatment approaches for breast cancer, including conventional receptor targeting methods and novel strategies like stimuli responsive methods and tumor micro-environment responsive strategies. This book compiles the most important information on the state-of-the-art therapeutics, including breast cancer biomarkers and design principles of bio-responsive nanosystems. Presented in two parts, sections cover basic and receptor mediated targeting approaches and examine tumor microenvironment mediated approaches. This is a useful book for pharmaceutical scientists and basic and clinical scientists working in the research ar...
This book describes recent developments concerning structural, functional and possible therapeutic aspects of one particular CAM, the neural cell adhesion molecule (NCAM).
This book presents the select proceedings of Congress on Advances in Materials Science and Engineering (CAMSE 2020). It focuses on the state-of-the-art research, development, and commercial prospective of recent advances in mechanical engineering. The book covers various synthesis and fabrication routes of functional and smart materials for applications in mechanical engineering, manufacturing, physics, chemical and biological sciences, metrology, optimization and artificial intelligence among others. This book will be a useful resource for researchers, academicians as well as professionals interested in the highly interdisciplinary field of materials science and mechanical engineering.
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Philology was everywhere and nowhere in classical South Asia. While its civilizations possessed remarkably sophisticated tools and methods of textual analysis, interpretation, and transmission, they lacked any sense of a common disciplinary or intellectual project uniting these; indeed they lacked a word for ‘philology’ altogether. Arguing that such pseudepigraphical genres as the Sanskrit purāṇas and tantras incorporated modes of philological reading and writing, Cox demonstrates the ways in which the production of these works in turn motivated the invention of new kinds of śāstric scholarship. Combining close textual analysis with wider theoretical concerns, Cox traces this philological transformation in the works of the dramaturgist Śāradātanaya, the celebrated Vaiṣṇava poet-theologian Veṅkaṭanātha, and the maverick Śaiva mystic Maheśvarānanda.