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Johann "Peter" Ruth was born ca. 1700 at Steinberg, Germany, the son of Johann Melchior and Maria Catharina Trein Ruth. Anna "Sophia" Lauer was born in 1703 at Hierstein, Germany, the daughter was Hans "Claus" and Maria "Margaretha" Wentz Lauer. Peter Ruth and Sophia Lauer were married in 1724 at Wolfersweiler, Germany. They had four sons, the first three born 1724-1728 at Walhausen, Germany. The family immigrated to America in 1733 and probably settled first in the Myerstown or Stouchsburg area of Berks County, Pennsylvania. After Sophia's death, he married 2) Catharin Mayer Meyer. They had ten children. He died in 1771 in Cumru Township, Berks County, Pennsylvania. Descendants of his oldest three sons lived in Pennsylvania, Illinois, and elsewhere.
For more than 100 years, Henry's Clinical Diagnosis and Management by Laboratory Methods has been recognized as the premier text in clinical laboratory medicine, widely used by both clinical pathologists and laboratory technicians. Leading experts in each testing discipline clearly explain procedures and how they are used both to formulate clinical diagnoses and to plan patient medical care and long-term management. Employing a multidisciplinary approach, it provides cutting-edge coverage of automation, informatics, molecular diagnostics, proteomics, laboratory management, and quality control, emphasizing new testing methodologies throughout. - Remains the most comprehensive and authoritativ...
Fibroblast Growth Factor 23 describes how FGF23 was initially identified as a bone-derived factor targeting the kidney. As such, sections in this comprehensive book cover exciting research that shows that different FGF23 effects require distinct signaling receptors and mediators that differ among target tissues, cover FGF23 initially identified as a bone-derived factor targeting the kidney, look at FGF23 as a regulator of phosphate metabolism and beyond, and cover research on novel concepts of FGF receptor signaling. Additional sections cover biochemistry, pharmacology and nephrology, making this book an ideal reference source on FGF23. - Provides a comprehensive collection of chapters on th...
αKlotho and fibroblast growth factor-23 (FGF23) were discovered independently about 20 years ago. Since their initial description, a series of exciting discoveries have revealed the important role of endocrine and paracrine FGF23 and αKlotho signaling not only for the physiological regulation of mineral and bone homeostasis, but also for the pathophysiology of diseases such as chronic kidney disease, left ventricular hypertrophy, myocardial infarction, hypertension, and disorders characterized by impaired bone mineralization. The 11 articles compiled in this Research Topic consist of three Original Research articles and 8 Reviews or Mini Reviews, and are an excellent source of information about the state of the art in the FGF23/αKlotho field, covering almost all aspects of FGF23/αKlotho biology.
- Continúa siendo el texto más completo y acreditado sobre todos los aspectos del laboratorio clínico, y los fundamentos científicos y la aplicación clínica de las pruebas de laboratorio. - Las actualizaciones incluyen los más recientes avances en las prácticas del laboratorio clínico, así como las aplicaciones nuevas y ampliadas al diagnóstico y la gestión. Los nuevos contenidos abarcan la espectrometría de masas, las pruebas de coagulación, la secuenciación de próxima generación, la medicina transfusional, la genética y el ADN libre de células, los anticuerpos dirigidos a los tumores, y las nuevas normativas, como la codificación CIE-10 para la facturación y el reembol...