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Diagnostic Nuclear Medicine and Radionuclide Therapy
Nuclear medicine is a medical imaging specialty involving the use of radioactive compounds for diagnostic and therapeutic purposes. As a medical branch, it is considered part of Diagnostic Imaging, but differs substantially from Radiology with respect to the source of the radiation made visible by the diagnostic devices. Nuclear medicine adopts also some types of radioactive emissions for therapeutic purposes, allowing the employment of the metabolic properties of the radiopharmaceuticals for the cure of certain clinical conditions and malignant diseases. Nuclear medicine is a relatively recent discipline and owes its origins to the discovery of natural radioactivity and the development of t...
Radiology for PET/CT Reporting
This atlas is intended to enable nuclear medicine practitioners who routinely read PET/CT scans to recognize the most common CT abnormalities. Reading PET/CT scans can sometimes be challenging. It is not infrequent, in fact, to encounter abnormal findings in CT images (not related to the neoplastic disease under evaluation) that are functionally silent and therefore difficult to interpret for nuclear medicine practitioners. Frequently, these findings are clinically relevant and should be reported, interpreted and compared to previous scans. This may also have an impact on patient management, since expensive tests like PET/CT are expected to provide the highest level of diagnostic information...
PET-CT Beyond FDG
Although [18F]fluorodeoxyglucose (FDG) generally shows an excellent performance as a cancer-imaging agent when using PET-CT, there are some settings in which other radiopharmaceuticals offer advantages. Such non-FDG tracers are now gaining widespread acceptance not only in research but also in clinical practice. This atlas, including about 500 high-quality images, is a user-friendly guide to PET-CT imaging beyond FDG. A wide range of tracers is covered, such as 18F- and 11C-choline, 11C-methionine, 18F-ethyl-L-tyrosine, 68Ga-DOTA-NOC, 11C-acetate, 11C-thymidine, and 18F-DOPA. Throughout, the emphasis is on image interpretation, with guidance on the recognition of normal, benign, and malignant uptake and clear instruction on learning points and pitfalls. This atlas is designed to serve as a reference text for both nuclear physicians and radiologists, and will also be of great benefit to radiographers, technologists, and nuclear medicine and radiology residents.
Atlas of SPECT-CT
The field of nuclear medicine has evolved rapidly in recent years, and one very important aspect of this progress has been the introduction of hybrid imaging systems. PET-CT has already gained widespread acceptance in many clinical settings, especially within oncology, and now SPECT-CT promises to emulate its success. Useful applications of this new approach have been identified not only in oncology but also in endocrinology, cardiology, internal medicine, and other specialties. This atlas, which includes hundreds of high-quality images, is a user-friendly guide to the optimal use and interpretation of SPECT-CT. The full range of potential SPECT-CT applications in clinical routine is considered and assessed by acknowledged experts. The book is designed to serve as a reference text for both nuclear physicians and radiologists; it will also provide fundamental support for radiographers, technologists, and nuclear medicine and radiology residents.
PET/CT in Neuroendocrine Tumors
This pocket book provides up-to-date descriptions of the most relevant features of neuroendocrine tumors (NETs) and the imaging modalities currently available to assist specialists (clinicians, pathologists, radiologists, nuclear medicine physicians) in selecting optimal patient management based on interdisciplinary collaboration. As the title indicates, the focus is particularly on PET/CT, with coverage of basic principles, the available radiopharmaceuticals, indications, typical and atypical appearances, normal variants and artifacts, advantages, limitations, and pitfalls. In addition, succinct information is provided on the use of other imaging modalities, including SPECT, CT, and MRI, and on pathology and treatment options. Imaging teaching cases are presented, and key points are highlighted throughout. The book is published as part of a series on hybrid imaging that is specifically aimed at referring clinicians, nuclear medicine/radiology physicians, radiographers/technologists, and nurses who routinely work in nuclear medicine and participate in multidisciplinary meetings.
Atlas of Response to Immunotherapy
This atlas is a concise but comprehensive guide to the diverse patterns of response to immunotherapy as observed on Positron Emission Tomography/Computed Tomography (PET/CT) and other conventional imaging modalities, including CT and Magnetic Resonance Imaging (MRI). The purpose for this publication is to fill the gap between the growing clinical relevance and utilization of immunotherapy in medical oncology, mainly based on checkpoint inhibitors, and the need for experienced imagers with reliable tools assessing response to treatment. A series of disease-oriented chapters will present the imaging findings during immunotherapy in the major oncological settings, with helpful comparison of fun...
Novel PET Imaging Techniques in the Management of Hematologic Malignancies, An Issue of PET Clinics
In this issue of PET Clinics, guest editors Drs. Cristina Nanni, Paolo Castellucci, Stefano Fanti, and Neeta Pandit-Taskar bring their considerable expertise to the topic of Novel PET Imaging Techniques in the Management of Hematological Malignancies. Top experts in the field discuss the latest radiotracers for lymphoma and myeloma, novel quantitative imaging techniques, radioligand therapies, total body PET imaging; and more. Contains 15 relevant, practice-oriented topics including PET imaging for therapy assessment in Hodgkin and non-Hodgkin lymphomas; symptomatic myeloma: PET, WB-MRI with DWI or both; advantages of total body PET imaging in hematological malignancies; applications of FDG-...
Philosophy of Advanced Medical Imaging
This is the first book to explore the epistemology and ethics of advanced imaging tests, in order to improve the critical understanding of the nature of knowledge they provide and the practical consequences of their utilization in healthcare. Advanced medical imaging tests, such as PET and MRI, have gained center stage in medical research and in patients’ care. They also increasingly raise questions that pertain to philosophy: What is required to be an expert in reading images? How are standards for interpretation to be fixed? Is there a problem of overutilization of such tests? How should uncertainty be communicated to patients? How to cope with incidental findings? This book is of interest and importance to scholars of philosophy of medicine at all levels, from undergraduates to researchers, to medical researchers and practitioners (radiologists and nuclear physicians) interested in a critical appraisal of the methodology of their discipline and in the ethical principles and consequences of their work.
Role of Medical Imaging in Cancers
The issue of Cancers Journal entitled “Role of Medical Imaging in Cancers” presents a detailed summary of evidences about molecular imaging, including the role of computed tomography (CT), magnetic resonance imaging (MRI), single photon emission tomography (SPET) and positron emission tomography (PET) or PET/CT or PET/MR imaging in many type of tumors (i.e. sarcoma, prostate, breast and others), motivating the role of these imaging modalities in different setting of disease and showing the recent developments, in terms of radiopharmaceuticals, software and artificial intelligence in this field. The collection of articles is very useful for many specialists, because it has been conceived for a multidisciplinary point of view, in order to drive to a personalized medicine.
PET-CT: Rare Findings and Diseases
PET-CT is increasingly being employed in the diagnosis of both oncological and non-oncological patients, yet nuclear medicine physicians may have only limited practical experience of rare diseases and may experience difficulty in recognizing and interpreting rare findings. This unique atlas documents a large number of clinical cases that will help practitioners to identify findings and diseases that, though rare, are sufficiently frequent to be encountered in routine practice. Two types of cases are presented: patients evaluated for rare diseases and patients evaluated for standard diseases in whom atypical PET findings were detected. Each reported case includes a brief description of the clinical history, representative color PET-CT images obtained using FDG or other tracers, and a short explanation of the disease and findings. This atlas will enable practitioners to make conclusive reports of PET-CT scans that would otherwise have been inconclusive.
